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4881
Investigating the Biological Impact of Melatonin on Male Albino Mice: A Comprehensive Characterization
Published 2025-01-01“…The review summarizes, this evidence implicates Mel in a broad range of effects with a significant regulatory influence over many of the body's physiological functions. Keywords: Blood serum, Medicinal plants, tryptophan, Rhamnaceae family, methanol, TLC and pineal gland. …”
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4882
Schistosoma japonicum Infection in Treg-Specific USP21 Knockout Mice
Published 2021-01-01“…The E3 deubiquitinating enzyme ubiquitin-specific proteolytic enzyme 21 (USP21) plays vital roles in physiological activities and is required for Treg-cell-mediated immune tolerance. …”
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4883
The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological stu...
Published 2022-07-01“…Material and methods: 60 male rats were divided into three groups of 20 rats: the control group (C) with no experimental periodontitis or treatment (gp1); ligature-induced periodontitis treated by SRP with a vehicle irrigation (dimethyl sulfoxide + physiological saline solution) group (gp2); and ligature-induced periodontitis treated by SRP with 10% PRO extract irrigation group (gp3). …”
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4884
A RESEARCH ON SOCIAL MEDIA ADDICTION AND DOPAMINE DRIVEN FEEDBACK
Published 2018-12-01“…Research has been conducted on changes in chemical movements and physiological behavior of individuals’ brain and nervous system. …”
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4885
Exploration of migration directions in different populations of Eothenomys miletus in the Hengduan Mountains of Yunnan Province: a genome-based analysis
Published 2025-01-01“…Eothenomys miletus is an endemic species that inhabits the Hengduan Mountain regions (HDR) and serves as one of the primary hosts for plague and hantaviruses. While the physiological characteristics of E. miletus have been extensively studied, the molecular aspects, particularly the migration direction of E. miletus, remain unclear. …”
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4886
Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice
Published 2025-01-01“…Thus, it is essential to develop a method by which the PCa initiation and progression timeline can be strictly controlled to mimic human physiological conditions. One milestone in this field was the identification of the prostate-specific transcription factor, Probasin (Pb), which allowed for the prostate-specific expression of genes knocked into the mice's genome. …”
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4887
Isolation of Prebiotics from Artocarpus integer’s Seed
Published 2021-01-01“…There has been a high amount of attention given to prebiotics due to their significant physiological function and health benefits. Prebiotics contain nondigestible compounds that allow specific changes, both in the growth and in the activity of bacteria in the host gastrointestinal tract, that provide benefits upon the host by promoting a healthy digestive system and preventing disease. …”
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4888
Intestinal microbiota shifts by dietary intervention during extreme heat summer episodes in farmed gilthead sea bream (Sparus aurata)
Published 2025-03-01“…Climate change and its associated extreme events alter a number of physiological processes that also affect the homeostatic relationship of the host with their microbial communities. …”
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4889
Design, Expression, and Inhibitory Effects of Antagonistic Single-Chain Platelet-Derived Growth Factor on Lung Cancer Cells
Published 2025-01-01“…Platelet-derived growth factor (PDGF) plays a pivotal role in numerous physiological and pathological conditions, acting as a dimeric disulfide-bound protein that induces receptor dimerization and subsequently activates cell signaling pathways. …”
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4890
Pharmacokinetic Properties of Baitouweng Decoction in Bama Miniature Pigs: Implications for Clinical Application in Humans
Published 2024-01-01“…Chinese Bama miniature pigs possess anatomical and physiological similarities to the human body, making them a valuable model for investigating PK properties. …”
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4891
Investigation of nosema apis and nosema ceranae in bees by multiplex pcr in kırıkkale region
Published 2023-12-01“…The thorax and abdomen of ten bees collected from every 5 colonies were dissected and crushed with sterile physiological water in a porcelain mortar. The samples with Nosema spores were stained with Saffron and the multiplex PCR was applied to detect specimens to the same samples.…”
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4892
Integrative analysis of single-cell and transcriptome sequencing with experimental validation reveals PKHD1L1 as a novel biomarker in lung adenocarcinoma
Published 2025-01-01“…Abstract Polycystic kidney and hepatic disease 1-like protein 1 (PKHD1L1) is predicted to encode a large type I transmembrane protein involved in hearing transmission and mediating cellular immunity under physiological conditions. However, its role in cancer progression, especially in lung adenocarcinoma (LUAD), has not been fully elucidated. …”
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4893
Peran Dukungan Keluarga sebagai Upaya Pengontrolan Hipertensi Pada Lansia
Published 2023-10-01“… As the elderly undergo physiological alterations during the aging process and are exposed to environmental influences that heighten their vulnerability to diseases, understanding the role of family support in mitigating health challenges, particularly hypertension, becomes paramount. …”
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4894
Systemic Thrombolysis for Treatment of Postpartum Saddle Embolism Complicated by Postpartum Hemorrhage: A Case Report and Brief Literature Review
Published 2021-01-01“…Due to the procoagulant physiological changes that occur, pregnancy and the postpartum period are known risk factors for thromboembolic events. …”
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4895
A Multicenter Observational Prospective Cohort Study of Association of the Prehospital National Early Warning Score 2 and Hospital Triage with Early Mortality
Published 2019-01-01“…We collected demographic, physiological, and clinical variables, main diagnosis, and hospital triage level as well as mortality. …”
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4896
Optimization of Video Stimuli Parameters in EMDR Therapy Using Artificial Neural Networks for Enhanced Treatment Efficacy
Published 2025-01-01“…Since then, EMDR has evolved into a personalized treatment focusing on stabilizing the physiological and psychological processes to alleviate symptoms of depression and stress. …”
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4897
Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer
Published 2022-01-01“…The commensal microbiota is involved in maintaining local pulmonary immune homeostasis under physiological conditions. Alterations in the amount and dominant species of the microbiota can reshape the immune response of the body and lead to a variety of lung diseases, including cancer. …”
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4898
Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors
Published 2020-01-01“…Adipose-derived stem cell (ADSC) is an alternative and less invasive source of mesenchymal stem cells which can be used to develop biological treatment strategies for tissue regeneration, and their therapeutic applications hinge on an understanding of their physiological characteristics. N6-Methyladenosine (m6A) is the most common chemical modification of mRNAs and has recently been revealed to play important roles in cell lineage differentiation and development. …”
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4899
Biallelic SLC13A1 loss-of-function variants result in impaired sulfate transport and skeletal phenotypes, including short stature, scoliosis, and skeletal dysplasia
Published 2025-01-01“…Purpose: Sulfate is vital for many physiological processes, including the structural and functional maintenance of macromolecules and formation of sulfur-containing compounds essential for cartilage and bone development. …”
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4900
Efficacy and Interindividual Variability in Motor-Cortex Plasticity following Anodal tDCS and Paired-Associative Stimulation
Published 2015-01-01“…Our findings highlight the need to define sufficient physiological read-outs for a given plasticity protocol and to develop predictive markers for targeted stimulation.…”
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