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4561
Intelligent health monitoring system based on smart clothing
Published 2018-08-01“…Eight kinds of services were provided by the system, including surveillance of signs of life, tracking of physiological functions, monitoring of the activity field, anti-lost, fall detection, emergency call for help, device wearing detection, and device low battery warning. …”
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4562
Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases
Published 2023-01-01“…They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals and plants. …”
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4563
Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
Published 2012-01-01“…Thus, it has been demonstrated that HIF prolyl hydroxylases are unlikely to be physiological targets of ROS and that the increase in ROS that is associated with downregulation of Thioredoxin Reductase in hypoxia does not affect HIF-1α stabilization. …”
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4564
Mammoplasty Using Modified Superomedial Pedicle Technique in Severely Macromastia and Ptotic Breasts
Published 2024-01-01“…Our results are more acceptable both cosmetically and physiologically. Therefore, the superomedial pedicle technique can be modified to achieve ideal results where free NAC mammoplasty is considered for severe macromastia and ptotic patients. …”
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4565
Calcium Phosphate Nanoparticles Functionalized with a Cardio-Specific Peptide
Published 2025-01-01“…Peptide-based therapies have demonstrated significant potential for treating CVDs; however, their clinical application is hindered by their limited stability in physiological fluids. To overcome this challenge, an effective drug delivery system is essential to protect and efficiently transport peptides to their intended targets. …”
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4566
Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans
Published 2017-01-01“…Our model sheds light on the versatility of the physiological functions of AtfA and its orthologs in fungi.…”
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4567
Nonviral targeted mRNA delivery: principles, progresses, and challenges
Published 2025-01-01“…In this review, we first described the physiological barriers in the process of mRNA delivery and then discussed the design approach and recent advances in mRNA delivery systems with an emphasis on their tissue/cell‐targeted abilities. …”
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4568
Temperature tolerance of European fish species based on thermal maxima in southern Baltic Sea-basin streams
Published 2025-01-01“…For all species, the upper limit of physiological endurance (lethal temperature) was clearly higher than the tolerance threshold. …”
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4569
Charge-Based Inhibitors of Amylin Fibrillization and Toxicity
Published 2015-01-01“…All three charge-loaded peptides fibrillize poorly on their own and inhibit fibril elongation of WT-amylin at physiological ionic strength. The inhibition of WT-amylin fibril elongation rates is salt-dependent indicating that the analogs act through electrostatic interactions. …”
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4570
Can carbonated water support weight loss?
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4571
The Structural, Biophysical, and Antigenic Characterization of the Goose Parvovirus Capsid
Published 2025-01-01“…Furthermore, the GPV capsid was found to be thermally stable at physiological pH, but less so under lower pH conditions. …”
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4572
Talent identification and development in judo: A systematic review
Published 2025-01-01“…Research in talent identification and development in judo has generally focused on individual constraints related to anthropometric and physiological characteristics, and technical skills in cross-sectional designs. …”
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4573
‘Ship-in-a-Bottle’ Integration of pH-Sensitive 3D Proteinaceous Meshes into Microfluidic Channels
Published 2025-01-01“…The sizes of these gaps changed when exposed to physiological buffers ranging from pH of 4 to 10. The size of the gaps in the mesh can be shrunk and expanded repeatedly by changing the pH of the surrounding buffer. …”
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4574
Psychological Distress in Out-Patients Assessed for Chronic Pain Compared to Those with Rheumatoid Arthritis
Published 2016-01-01“…Level of psychological distress based on the subscales of the DASS (depression, anxiety, and stress), PASS (escape avoidance, cognitive anxiety, fear of pain, and physiological anxiety), and PCS (rumination, magnification, and helplessness) was significantly higher in the CP group compared to the RA group. …”
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4575
The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling
Published 2015-01-01“…Modeling interactions between aggregates and B cell receptors demonstrated that aggregates are unlikely to induce T cell-independent immune responses by cross-linking B cell receptors because the amount of signal transducing complex that can form under physiologically relevant conditions is limited. We systematically evaluate the role of aggregates in inducing T cell-dependent immune responses using a recently developed multiscale mechanistic mathematical model. …”
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4576
Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (<i>Cucumis melo</i> L.) Seedlings
Published 2024-12-01“…This study aimed to find out the effects of HA treatment on the morphological, physiological, and nitrogen metabolism of melon seedlings under low-temperature stress. …”
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4577
Symptom Status Predicts Patient Outcomes in Persons with HIV and Comorbid Liver Disease
Published 2012-01-01“…The model components include biological/physiological factors (HIV viral load, CD4 counts), symptom status (Beck Depression Inventory II and the Medical Outcomes Study HIV Health Survey (MOS-HIV) mental function), functional status (missed appointments and MOS-HIV physical function), general health perceptions (perceived burden visual analogue scale and MOS-HIV health transition), and overall quality of life (QOL) (Satisfaction with Life Scale and MOS-HIV overall QOL). …”
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4578
A Fast Testing Method to Objectively Quantify the Stiffness of Stability Boots
Published 2015-01-01“…The range of motion (RoM) was then assessed during 5 trials at physiological ankle joint torques during flexion/extension and inversion/eversion. …”
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4579
Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice
Published 2015-01-01“…Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome based on genetic analysis of knockout mice.…”
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4580
Pyrogallol-Phloroglucinol-6, 6-Bieckol Restored Primary Cilia Length, Which Was Decreased by High-Fat Diet in Visceral Adipose Tissue, and Decreased Adipogenesis
Published 2022-01-01“…ECE and PPB decreased physiological changes, which increased by HFD, but ECE and PPB decreased the upregulation of the IL-6/STAT3/AURKA signaling pathway, which is involved in cilia disassembly. …”
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