Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease. by Asgeir Kobro-Flatmoen, Stig W Omholt

“…If reelin functions as a sink for intracellular Aβ and if the binding to reelin makes Aβ physiologically inert, it implies that reelin can prevent the neuron from being exposed to the harmful effects typically associated with increased levels of oligomeric Aβ. …”
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Blood Genome-Wide Transcriptional Profiles of HER2 Negative Breast Cancers Patients by Ovidiu Balacescu, Loredana Balacescu, Oana Virtic, Simona Visan, Claudia Gherman, Flaviu Drigla, Laura Pop, Gabriela Bolba-Morar, Carmen Lisencu, Bogdan Fetica, Oana Tudoran, Ioana Berindan-Neagoe

“…Tumors act systemically to sustain cancer progression, affecting the physiological processes in the host and triggering responses in the blood circulating cells. …”
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Targeting cryptic allosteric sites of G protein-coupled receptors as a novel strategy for biased drug discovery by Xin Qiao, Xiaolong Li, Mingyang Zhang, Ning Liu, Yanmei Wu, Shaoyong Lu, Ting Chen

“…GPCRs couple different downstream effectors, including G proteins (such as Gi/o, Gs, G12, and Gq) and β-arrestins (such as β-arrestin 1 and β-arrestin 2) to mediate diverse cellular and physiological responses. Biased signaling allows for the specific activation of certain pathways from the full range of receptors’ signaling capabilities. …”
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Omics based technology application in poultry meat research by Huaijun Zhou, Austin Quach, Mahesh Nair, Behnam Abasht, Byungwhi Kong, Brian Bowker

“…These approaches have been extensively utilized to identify both biomarkers and biological mechanisms for various physiological conditions in livestock and poultry. The purpose of this symposium was not only to focus on how recent omics technologies can be used to gather, integrate, and interpret data produced by various methodologies in poultry research, but also to highlight how omics and bioinformatics have increased our understanding of poultry meat quality problems and other complex traits. …”
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Studying the effect of the OsGATA rice transcription factor on salt stress tolerance in wheat by A. A. Verbitskaia, A. S. Egorova, E. A. Tsarkova, A. K. Gaponenko

“…This study shows the possibility of using the OsGATA rice transcription factor in transgenic lines of high-yielding wheat cultivars to increase their tolerance to salinity, which was confirmed using physiological and biochemical methods according to standard protocols. …”
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Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback by Hatice Kumru, Sergiu Albu, Raul Pelayo, John Rothwell, Eloy Opisso, Daniel Leon, Dolor Soler, Josep Maria Tormos

“…Plasticity is one of the most important physiological mechanisms underlying motor recovery from brain lesions. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…Here it is demonstrated that dynamic light scattering (DLS) is sensitive and effective at measuring variation in lipoprotein size distributions following oxidative damage caused by peroxidation and nitration—two common physiological processes that play dual roles in both normal and pathogenic states. …”
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Extraction of Psychological Effects of COVID-19 Pandemic through Topic-Level Sentiment Dynamics by Abdul Razzaq, Touqeer Abbas, Sarfraz Hashim, Salman Qadri, Imran Mumtaz, Najia Saher, Muzammil Ul-Rehman, Faisal Shahzad, Syed Ali Nawaz

“…The proposed framework illustrates the insight impact of COVID-19 on human physiological and mainly focuses on the evaluation of sentiment dynamics at the topical level.…”
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Effects of Soil Quality Enhancement on Pollinator-Plant Interactions by Yasmin J. Cardoza, Gabriel K. Harris, Christina M. Grozinger

“…We studied the effects of vermicompost (earthworm compost, VC) soil amendment on behavioral and physiological responses of pollinators to flowers and floral resources, using cucumbers, Cucumis sativus, as our model system. …”
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Application of mean maximum Young’s modulus value as a new parameter for differential diagnosis of prostate diseases by Nailei Huang, Xinge Cao, Zhong Li, Haoyu Wang, Wei Zhao, Jun Shi

“…The relationship between m-Emax and prostate disease was consistent with the nonlinear effect showed by tissues as an elastic model in normal physiological activity areas. When stiffness increasing, the stress-strain relationship was approximates linear. …”
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Modification of Human-Biometeorologically Significant Radiant Flux Densities by Shading as Local Method to Mitigate Heat Stress in Summer within Urban Street Canyons by Hyunjung Lee, Jutta Holst, Helmut Mayer

“…Urban human-biometeorology stands for the variables air temperature Ta, mean radiant temperature Tmrt, and physiologically equivalent temperature PET, that is the human-biometeorological concept to assess the thermal environment which was applied. …”
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Falls Risk and Simulated Driving Performance in Older Adults by John G. Gaspar, Mark B. Neider, Arthur F. Kramer

“…Participants were classified as high or low falls risk using the Physiological Profile Assessment and completed a number of challenging simulated driving assessments in which they responded quickly to unexpected events. …”
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A comprehensive insight of innovations and recent advancements in nanocarriers for nose-to-brain drug targeting by Naeem Mubarak, Muhammad Ahsan Waqar, Asad Majeed Khan, Zainab Asif, Aima Subia Alvi, Aqsa Arshad Virk, Sakeena Amir

“…These nanocarriers are designed to overcome physiological barriers and provide controlled and sustained drug release directly to the CNS. …”
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Mobility of social processes as a resource of society. Correlation of the concepts of pathology, deviation, mutations by S. I. Shlyapin

“…The last approach was the physiological (anthropological) one. From its points of  view, it   is said about a   difference in  the origin of  the races of   people, hence the likely deviation. …”
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A new negative air ion smoke suppression purifier for purifying fire smoke in road tunnel based on corona discharge by Shouzhong Feng, Deyuan Kan, Zhiguo Yan, Weixing Mao, Long Zhou

“…Additionally, an eye tracker was employed to record the pupil change data of the testers before and after the negative ion smoke suppression purifier was used to measure changes in pupil diameter before and after activating the purifier system to evaluate its impact on alleviating the physiological and psychological stress of individuals in the fire environment. …”
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Survival of Wild Strains of Lactobacilli During Kombucha Fermentation and Their Contribution to Functional Characteristics of Beverage by Dragoljub Cvetković, Aleksandra Ranitović, Dragiša Savić, Nataša Joković, Ana Vidaković, Lato Pezo, Siniša Markov

“…The addition of wild Lactobacillus spp. during Kombucha fermentation had no effect on the physiological activity of tea fungus, but they contributed to a significant increase in lactic acid content in the beverage. …”
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Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus. by Antonio Jordán-Pla, Yujie Zhang, José García-Martínez, Shiladitya Chattopadhyay, Anabel Forte, Mordechai Choder, Vicent Pelechano, José E Pérez-Ortín

“…Furthermore, a principal component analysis of the genomic datasets of this mutant and other Xrn1 mutants also shows that lack of a cytoplasmic 5'→3' exoribonuclease is the primary cause of the physiological defects seen in a xrn1Δ mutant, but also suggests that Xrn1 import into the nucleus is necessary for its full in vivo functions.…”
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Are the Mesothelial-to-Mesenchymal Transition, Sclerotic Peritonitis Syndromes, and Encapsulating Peritoneal Sclerosis Part of the Same Process? by Jesús Loureiro, Guadalupe Gónzalez-Mateo, José Jimenez-Heffernan, Rafael Selgas, Manuel López-Cabrera, Abelardo Aguilera Peralta

“…Mesothelial-to-mesenchymal transition (MMT) is an autoregulated physiological process of tissue repair that in uncontrolled conditions, such as peritoneal dialysis (PD), can lead to peritoneal fibrosis. …”
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Molecular dynamics and machine learning unlock possibilities in beauty design—A perspective by Yuzhi Xu, Haowei Ni, Fanyu Zhao, Qinhui Gao, Ziqing Zhao, Chia-Hua Chang, Yanran Huo, Shiyu Hu, Yike Zhang, Radu Grovu, Hermione He, John Z. H. Zhang, Yuanqing Wang

“…In the small data regime, physics-based approaches model the interaction between the molecule being designed and proteins of key physiological functions, providing structural insights into the mechanism. …”
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Heavy Metal Stress and Some Mechanisms of Plant Defense Response by Abolghassem Emamverdian, Yulong Ding, Farzad Mokhberdoran, Yinfeng Xie

“…This would inflict serious morphological, metabolic, and physiological anomalies in plants ranging from chlorosis of shoot to lipid peroxidation and protein degradation. …”
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