Association between microplastics and the functionalities of human gut microbiome by Bei Gao, Lixia Chen, Lizhi Wu, Shirui Zhang, Sunan Zhao, Zhe Mo, Zhijian Chen, Pengcheng Tu

“…As an integral part of humans, the gut microbiome plays a significant role in the physiological and pathological processes of the host, and dysbiosis of the gut microbiome is linked to various diseases. …”
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Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology by Alise Zagare, Janis Kurlovics, Catarina Almeida, Daniele Ferrante, Daniela Frangenberg, Armelle Vitali, Gemma Gomez-Giro, Christian Jäger, Paul Antony, Rashi Halder, Rejko Krüger, Enrico Glaab, Egils Stalidzans, Giuseppe Arena, Jens C Schwamborn

“…To investigate insulin resistance caused pathological changes in the human midbrain, which could predispose a healthy midbrain to PD development, we exposed iPSC-derived human midbrain organoids from healthy individuals to either high insulin concentration, promoting insulin resistance, or to more physiological insulin concentration restoring insulin signalling function. …”
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Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges by Inga Brockmann, Juliet Ehrenpfordt, Tabea Sturmheit, Matthias Brandenburger, Charli Kruse, Marietta Zille, Dorothee Rose, Johannes Boltze

“…These cells promote wound healing under physiological conditions and are potential sources for tissue engineering approaches aiming to augment transplantable tissue by generating cultured epidermal autografts (CEAs). …”
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An Improved Quantitative Analysis Method for Plant Cortical Microtubules by Yi Lu, Chenyang Huang, Jia Wang, Peng Shang

“…The arrangement of plant cortical microtubules can reflect the physiological state of cells. However, little attention has been paid to the image quantitative analysis of plant cortical microtubules so far. …”
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Gut-Lung Microbiota in Chronic Pulmonary Diseases: Evolution, Pathogenesis, and Therapeutics by Chang Yi Shi, Chen Huan Yu, Wen Ying Yu, Hua Zhong Ying

“…The microbiota colonized in the human body has a symbiotic relationship with human body and forms a different microecosystem, which affects human immunity, metabolism, endocrine, and other physiological processes. The imbalance of microbiota is usually linked to the aberrant immune responses and inflammation, which eventually promotes the occurrence and development of respiratory diseases. …”
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Configuration Synthesis and Performance Analysis of Finger Soft Actuator by Ziqiang Zhang, Hanlong Chen, Zining Zhang

“…The configuration synthesis method for soft actuator was proposed based on the analysis of the physiological structure of the finger, and the soft actuator can make the human-machine closed-loop structure including n joints (n=1, 2, 3) meet the requirement of DOF (degrees of freedom). …”
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Biopharmaceutical classification of desloratadine – not all drugs are classified the easy way by Berginc Katja, Sibinovska Nadica, Žakelj Simon, Trontelj Jurij, Legen Igor

“…We have demonstrated deslorata-dine stability under legally required conditions and also in more physiologically relevant media. High in vitro desloratadine permeability was confirmed using Caco-2 and Parallel Artificial Membrane Permeability Assay (PAMPA). …”
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Challenges in the application of Maslow’s hierarchy of needs for children living in Gaza amid ongoing conflict started in October 2023 by Mohammed Qutishat

“…The findings highlight critical challenges across all levels of Maslow’s hierarchy. Physiological needs remain unmet due to food insecurity and limited access to healthcare. …”
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The Role of Neuroglia in the Development and Progression of Schizophrenia by Neha S. Rawani, Allen W. Chan, Kathryn G. Todd, Glen B. Baker, Serdar M. Dursun

“…Although glia were originally thought to be present in the brain only to support neurons in a physical, metabolic and nutritional capacity, it has become apparent that these cells have a variety of important physiological roles and that abnormalities in their function may make significant contributions to the symptoms of schizophrenia. …”
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Understanding and Prevention of “Therapy-” Induced Dyskinesias by Iciar Aviles-Olmos, Zinovia Kefalopoulou, Thomas Foltynie

“…LID results from nonphysiological dopamine release, supersensitivity of dopamine receptors, and consequent abnormal signalling through mechanisms of synaptic plasticity. Restoration of physiological circuitry within the basal ganglia loops is ultimately the aim of all cell and gene therapy approaches but each using distinctive strategies and accompanied by risks of exacerbation of LID or development of “off-phase”/GID. …”
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Antioxidant Potential Overviews of Secondary Metabolites (Polyphenols) in Fruits by Mohammed Sharif Swallah, He Sun, Raïfatou Affoh, Hongling Fu, Hansong Yu

“…Future studies are required to help identify the physiological metabolic activities as well as to improve human health.…”
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The Precapillary Segment of the Blood-Brain Barrier and Its Relation to Perivascular Drainage in Alzheimer's Disease and Small Vessel Disease. by Dietmar R. Thal

“…At the arteries and veins the BBB is thicker and there is, under physiological conditions, no direct transport from the brain tissue to the blood or vice versa. …”
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Auricular bioelectronic devices for health, medicine, and human-computer interfaces by William J. Tyler

“…This review article discusses recent design and engineering advances in the development of auricular bioelectronic devices capable of physiological and biochemical sensing, cognitive monitoring, targeted neuromodulation, and control for human-computer interactions. …”
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Innovations in intestinal organoid technology featuring an open apical surface by Ye Chen, Yi Wang

“…Since the development of the three-dimensional (3D) “mini-gut” culture system, adult stem cell-derived organoid technology has rapidly advanced, providing in vitro models that replicate key cellular, molecular, and physiological properties of multiple organs. The 3D intestinal organoid system has resolved many long-standing challenges associated with immortalized or cancer cell cultures, offering unparalleled capabilities for modeling gastrointestinal development and diseases. …”
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Response growth and yield of local black rice variety mutiara to drought stress by Purwanto Edi, Taqiy Apta Danendra Faiq, Cahyo Handoyo Gani, Rahayu Muji

“…Plant tolerance under drought stress has mechanisms to adapt to adverse impacts such as synthesizing proline compounds, increasing root length, changing physiological processes, inhibiting growth, and reducing yield of paddy. …”
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The Clinical Significance of Exhaled Nitric Oxide in Asthma by Sachin Pendharkar, Sanjay Mehta

“…In the present paper, the relationship of elevated eNO levels in asthma with inflammatory, physiological and clinical markers of asthma in adults was reviewed. …”
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The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control by Jean-Philippe Guégan, Christophe Frémin, Georges Baffet

“…The models mimic the physiological process of hepatic regeneration after liver injury or partial hepatectomy. …”
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Periodontal Care as a Fundamental Step for an Active and Healthy Ageing by Carlo Cafiero, Marco Matarasso, Gaetano Marenzi, Vincenzo Iorio Siciliano, Loredana Bellia, Gilberto Sammartino

“…In the industrialized part of the world, an increasing number of people live the old age without too many restrictions due to illness or physiological impairment. This group is known as the young elderly. …”
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Randomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity by Hiroko Ochiai, Shigeru Inoue, Gaku Masuda, Shiho Amagasa, Tomohiko Sugishita, Toshiya Ochiai, Naoko Yanagisawa, Yoshio Nakata, Michiko Imai

“…We conducted an unblinded randomized controlled trial involving healthy men aged 40–70 to compare the physiological and psychological effects of forest and urban walking. …”
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Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia by Teik K. Ho, X. Shiwen, D. Abraham, J. Tsui, D. Baker

“…The chemokine stromal-cell-derived factor-1 (SDF-1 aka CXCL12) is a constitutively expressed and inducible chemokine that regulates multiple physiological processes, including embryonic development and organ homeostasis. …”
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