Symposium on Obesity and Asthma –November 2, 2006 by Louis-Philippe Boulet, Qutayba Hamid

“…It includes an overview of the various aspects of the relationships between asthma and obesity with regard to animal models; genetic, hormonal and physiological determinants; influence of comorbidities (eg, sleep apnea syndrome); epidemiology; clinical and psychological features; and management of asthma in the obese population.…”
Get full text

The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective by Midori Umekawa, Daniel J. Klionsky

“…From today's perspective, it is obvious that macroautophagy (hereafter autophagy) is an important pathway that is connected to a range of developmental and physiological processes. This viewpoint, however, is relatively recent, coinciding with the molecular identification of autophagy-related (Atg) components that function as the protein machinery that drives the dynamic membrane events of autophagy. …”
Get full text

Interaction of Hyperoside with Human Serum Albumin and Effect of Glucose on the Binding by Jie Yang, Lingling Qu, Wenyue Yang, Yun Huang, Ning Jiao, Wenhong Zhan, Ding Zhao, Lijian Cui

“…The interaction of hyperoside (Hyp) with human serum albumin (HSA) and effect of glucose on the binding were studied in simulating physiological condition (pH 7.40). The results suggested that Hyp quenched the endogenous fluorescence of HSA via a static quenching process with the distance of 1.95 nm between Hyp and HSA. …”
Get full text

Assessment of Food Security in the East Kazakhstan Region by Aigerim Duisenbekova, Alina Daniłowska

“…In the analyses, criteria such as the level of the region’s food independence, the degree of satisfaction of the population’s physiological needs in basic food, and the level of economic availability of food were applied. …”
Get full text

Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease by Yi Wang, Feng Xu, Jia-Yu Zhong, Xiao Lin, Su-Kang Shan, Bei Guo, Ming-Hui Zheng, Ling-Qing Yuan

“…Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell, reflecting a novel physiological and pathological mechanism in disease development. …”
Get full text

Role of PPARα in the Control of Torpor through FGF21-NPY Pathway: From Circadian Clock to Seasonal Change in Mammals by Norio Ishida

“…Torpor is a state of decreased physiological activity in an animal, usually characterized by a reduced body temperature and rate of metabolism to adapt such a severe environment. …”
Get full text

Intracytoplasmic Crystalline Inclusions in the Hepatocytes of an Antelope by Sanjeev Gumber, Eric Lombardini, Bruce Williams, Nobuko Wakamatsu

“…It was concluded that crystalline inclusions may have been derived due to failure of normal physiological hepatocellular clearance associated with a severe chronic disease. …”
Get full text

Metals and Breast Cancer: Risk Factors or Healing Agents? by Ana-Maria Florea, Dietrich Büsselberg

“…Several metals are essential for physiological functions (e.g., zinc or magnesium); while the beneficial effects of others are uncertain (e.g., manganese), some metals are proven to be toxic (e.g., mercury, lead). …”
Get full text

PROSPECTION OF FILAMENTOUS FUNGI AND THE PRODUCTION OF AMYLASE BY ASPERGILLUS sp. M1.7.2 by Mariana Tainná Silva Souza, Barbhara Mota Marinho, Thiago Machado Pasin, David Lee Nelson, Vivian Machado Benassi

“…This work aimed to prospect filamentous fungi, analyze the morphological and physiological characteristics of the isolates; as well as to select an amylase producing fungus and to optimize the parameters for the cultivation of the microorganism and biochemically characterize the amylase. …”
Get full text

Designing an Efficient System for Emotion Recognition Using CNN by Donia Ammous, Achraf Chabbouh, Awatef Edhib, Ahmed Chaari, Fahmi Kammoun, Nouri Masmoudi

“…It could be related to the mental or physiological state of mind. This paper mainly focuses on a human emotion recognition system through a detected human face. …”
Get full text

How does the tea L-theanine buffer stress and anxiety by Liwen Wang, Margaret Brennan, Shiming Li, Hui Zhao, Klaus W. Lange, Charles Brennan

“…The biological efficacy of dietary L-theanine in the food matrix has been further discussed in this review in relation to the physiological changes in the gastrointestinal tract and bindings of L-theanine with other food components.…”
Get full text

Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy by O. Lorenzo, E. Ramírez, B. Picatoste, J. Egido, J. Tuñón

“…However, the presence of these species can be essential for physiological responses in the diabetic myocardium.…”
Get full text

The Implications of Mental Health and Trauma in Interstitial Cystitis by Tyler R. Bendrick, Graison L. Sitenga, Cameron Booth, Matthew P. Sacco, Christine Erie, Danyon J. Anderson, Alan D. Kaye, Ivan Urits

“…We describe three distinct hypotheses for the possible physiologic mechanism for development of IC with relation to mental health and trauma, although definitive evidence in this area is still lacking, which poses interesting avenues for further research. …”
Get full text

Targeted drug delivery in neurodegenerative diseases: the role of nanotechnology by Rupal Dhariwal, Rupal Dhariwal, Mukul Jain, Mukul Jain, Yaser Rafiq Mir, Abhayveer Singh, Bhavik Jain, Pankaj Kumar, Mohd Tariq, Mohd Tariq, Devvret Verma, Khemraj Deshmukh, Virendra Kumar Yadav, Tabarak Malik, Tabarak Malik

“…This study explores the potential of nanotherapeutics as a promising approach to enhance drug delivery across physiological barriers, particularly the blood–brain barrier (BBB) and blood-cerebrospinal fluid barrier (B-CSFB). …”
Get full text

Lipophilic bioactive compounds nano-micro encapsulation via coaxial electrohydrodynamic atomization: A review by Elnaz Z. Fallahasghari, Ioannis S. Chronakis, Ana C. Mendes

“…Natural lipophilic bioactive compounds, which are essential for various physiological functions, present challenges in processing and formulation due to their physicochemical properties. …”
Get full text

GABAergic Neuron Specification in the Spinal Cord, the Cerebellum, and the Cochlear Nucleus by Kei Hori, Mikio Hoshino

“…In the nervous system, there are a wide variety of neuronal cell types that have morphologically, physiologically, and histochemically different characteristics. …”
Get full text

Mitochondrial Dysfunction and Diabetic Nephropathy: Nontraditional Therapeutic Opportunities by Ping Na Zhang, Meng Qi Zhou, Jing Guo, Hui Juan Zheng, Jingyi Tang, Chao Zhang, Yu Ning Liu, Wei Jing Liu, Yao Xian Wang

“…In this review, we have surveyed recent advances in elucidating the mitochondrial networking and signaling pathways in physiological and pathological contexts. Additionally, we have considered the contributions of nontraditional therapy that ameliorate mitochondrial dysfunction and discussed their molecular mechanism, highlighting the potential value of nontraditional therapies, such as herbal medicine and lifestyle interventions, in therapeutic interventions for DN. …”
Get full text

When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells by Fuquan Chen, Jiaojiao Ji, Jian Shen, Xinyi Lu

“…Long noncoding RNAs (lncRNAs) were known for their influential regulatory roles in multiple biological processes such as imprinting, dosage compensation, transcriptional regulation, and splicing. The physiological functions of protein-coding genes have been extensively characterized through genome editing in pluripotent stem cells (PSCs) in the past 30 years; however, the study of lncRNAs with genome editing technologies only came into attentions in recent years. …”
Get full text

Gastroesophageal reflux. by Yanet Hidalgo Marrero, Rafael Trinchet Soler, Lauro A. Melo Aguilera

“…Near 90% of children vomits during the first 6 weeks of life, due primarily to the physiologic immaturity of antireflux mechanism. However, in 60% of cases, reflux disappears before 18 months, even without treatment. 30% maintains the symptoms, becoming in pathological, and of them, 10% develops serious problems, around 5% esophagitis with stenosis and between the 1 to 5% the death related with aspiration. …”
Get full text

Metabolism of bile acids, liver diseases and microbiome by Yu. V. Yevsyutina, V. T. Ivashkin

“…Bile acids carry out multiple physiological functions. The link between BA metabolism, liver disease and intestinal microbiome is demonstrated by numerous investigations.…”
Get full text