Characterization of Thirty Germplasms of Millet Pepper (<i>Capsicum frutescens</i> L.) in Terms of Fruit Morphology, Capsaicinoids, and Nutritional Components by Ruihao Zhang, Mengjuan Li, Junheng Lv, Pingping Li, Yunrong Mo, Xiang Zhang, Hong Cheng, Qiaoling Deng, Min Gui, Minghua Deng

“…PCA analysis using phenotypic data and physicochemical data showed that the classification results were different. …”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma &le;3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Elevated Platelet-CRP Score(PCS), integrating CRP and PLT, correlated significantly with an increased incidence of RBM and a more aggressive phenotype, characterized by vascular invasion or metastatic dissemination (P< 0.05). …”
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T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates by Joanna M. Schaenman, MD, PhD, Harry Pickering, PhD, Elaine F. Reed, PhD, Maura Rossetti, PhD, Benjamin Seligman, MD, S. Samuel Weigt, MD, Michael Shino, MD, David Sayah, MD, PhD, John Belperio, MD, Ashley Hu, MD, Ashley Prosper, MD, Kathleen Ruchalski, MD, Abbas Ardehali, MD, Reshma Biniwale, MD

“…Frailty was measured using the Fried Frailty Phenotype. Immune phenotyping was performed using multichannel flow cytometry of peripheral blood mononuclear cells (PBMC) in a total of 26 lung transplant candidates. …”
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Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15 by Jianyan Pan, Hua Teng, Fang Liu, Siyi Chen, Yaning Liu, Yanling Teng, Desheng Liang, Zhuo Li, Lingqian Wu

“…In this study, A four-generation Chinese family with 11 patients manifesting late-onset progressive non-syndromic hearing loss was recruited. The phenotype of hearing loss in this family showed a large variability in terms of onset age and progression speed. …”
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Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1... by Wangcheng Hu, Hui Luo, Yuekun Yang, Qiong Wang, Ni Hong, Guoping Wang, Aiming Wang, Liping Wang

“…BdCV1 had a greater effect on the phenotype, virulence, conidiomata, vertical and horizontal transmission ability, and mycelia cellular structure biological characteristics of B. dothidea strains than BdPV1 and virus-free strains. …”
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Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1 by Jessica Purizaca, Adriana Contreras-Quiroz, Elisa Dorantes-Acosta, Eduardo Vadillo, Lourdes Arriaga-Pizano, Silvestre Fuentes-Figueroa, Horacio Villagomez-Barragán, Patricia Flores-Guzmán, Antonio Alvarado-Moreno, Hector Mayani, Isaura Meza, Rosaura Hernandez, Sara Huerta-Yepez, Rosana Pelayo

“…The aim of the present study was to investigate the ability of lymphoid progenitors from B-cell precursor ALL BM to proliferate and undergo multilineage differentiation. By phenotype analyses, in vitro proliferation assays, and controlled culture systems, the lymphoid differentiation potentials were evaluated in BM primitive populations from B-cell precursor ALL pediatric patients. …”
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Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study by Julien Greggio, Christina Malamateniou, Kelly Pegoretti Baruteau, Constantino Carlos Reyes-Aldasoro, Odaro J. Huckstep, Jane M. Francis, Wilby Williamson, Paul Leeson, Adam J. Lewandowski, Winok Lapidaire

“…Conclusions Preterm birth is linked to a distinct vascular phenotype of CoW in adults born preterm, with a higher likelihood of a CoW configuration with hypoplastic segments but a lower likelihood of absent segments. …”
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Clinical spectrum, treatment and outcomes of the m.10197G>A mutation in MT-ND3: a case report, systematic review and meta-analysis by YuZhi Shi, Bin Chen, SongTao Niu, XinGao Wang, ZaiQiang Zhang

“…The identification of factors and outcomes associated with phenotypes in patients with the m.10197G>A mutation facilitates the provision of improved prognostic counseling for patients and their family members who are carriers of this mutation.…”
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Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines by Anton Wellstein, Thomas Seufferlein, Alexander Kleger, Tim Eiseler, Anton Lahusen, Nora Minhöfer, Kim-André Lohse, Christine Blechner, Jessica Lindenmayer, Sabine Windhorst, Yuan-Na Lin

“…A combination of transcriptomic analyses, cytometric and immunohistochemistry techniques allowed us to validate the underlying T cell response phenotypes of PDAC cells. The action of TGM2 via interaction with tubulin and the impact of microtubule dynamics and vesicle trafficking were evaluated by protein analyses and live-cell imaging. …”
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NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity by Yingying Xiong, Yiming Weng, Shan Zhu, Jian Qin, Jia Feng, Xiaopeng Jing, Chao Luo, Wei Gong, Rui Sun, Min Peng

“…Loss of NOX4 promotes a more malignant phenotype and dampens T cell responses, whereas its overexpression prolongs survival and enhances checkpoint inhibitor efficacy. …”
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Biofilm Formation by Staphylococcus aureus Isolated from Food Contact Surfaces in the Dairy Industry of Jalisco, Mexico by María-Guadalupe Avila-Novoa, Maricarmen Iñíguez-Moreno, Oscar-Alberto Solís-Velázquez, Jean-Pierre González-Gómez, Pedro-Javier Guerrero-Medina, Melesio Gutiérrez-Lomelí

“…The isolates were characterized phenotypically by culture on Congo red agar plates. The ability of the strains to form biofilms was investigated in 96-well flat-bottomed microtiter polystyrene plates. …”
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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…However, the role of the OPTN gene in ALS caused by SOD1 mutations is ambiguous.MethodsThe murine Optn lentivirus and empty vector lentivirus were injected into SOD1G93A mice after discovering variations in Optn expression over time. The phenotype onset date, life span, locomotor activity, and pathological changes in the spinal cord were determined and recorded subsequently. …”
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Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2 by Yan Long, Chenghan Wang, Jie Xiao, Yunhua Huang, Xiaoting Ling, Chaoyu Huang, Ying Chen, Jiaqi Luo, Rongheng Tang, Faquan Lin, Yifang Huang

“…This study aimed to investigate the phenotype and immune function of a girl with ICF2, identify her genetic defect, and explore the potential pathogenic mechanisms of the disease. …”
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Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia by Chiara Catozzi, Francesca Stretti, Enrica Scalera, Matteo Storti, Angelo Modena, Giorgio Aquila, Gino Villetti, Erica Ferrini, Andrea Grandi, Franco Fabio Stellari, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Christina Brandenberger, Henri Schulte, Xabier Murgia, Maurizio Civelli, Francesca Ricci

“…Results Premature birth itself, without any other BPD hit, was associated with lung function deficits, delayed lung development, and cardiovascular abnormalities. The BPD-like lung phenotype was enhanced by 70% O2 but not by 50% O2 hyperoxia. …”
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Loading of CAR‐T cells with magnetic nanoparticles for controlled targeting suppresses inflammatory cytokine release and switches tumor cell death mechanism by Felix Pfister, Lucas R. Carnell, Lisa Löffler, Philipp Boosz, Niels Schaft, Jan Dörrie, René Stein, Malte Lenz, Erdmann Spiecker, Christian M. Huber, Sami Haddadin, Carola Berking, Christoph Alexiou, Christina Janko

“…Importantly, SPIONs suppressed cytokine release in the loaded CAR‐T cells, shifting the cell death phenotype in the tumor cells from pyroptosis to apoptosis. …”
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Probing the Dual Role of Ca²⁺ in the <i>Allochromatium tepidum</i> LH1–RC Complex by Constructing and Analyzing Ca²⁺-Bound and Ca²⁺-Free LH1 Comple... by Mei-Juan Zou, Shuai Sun, Guang-Lei Wang, Yi-Hao Yan, Wei Ji, Zheng-Yu Wang-Otomo, Michael T. Madigan, Long-Jiang Yu

“…The <i>Alc. tepidum</i> LH1, therefore, offers a unique model for studying an intermediate phenotype between phototrophic thermophilic and mesophilic bacteria, particularly regarding their LH1 <i>Qy</i> transition and moderately enhanced thermal stability. …”
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Secondary vs. primary pituitary xanthogranulomas: which yellow is more mellow? by Dragana Miljic, Sandra Pekic, Mirjana Doknic, Marko Stojanovic, Sasa Ilic, Marina Nikolic Djurovic, Zvezdana Jemuovic, Toplica Milojevic, Mihailo Milicevic, Marija Jovanovic, Milica Medic Stojanoska, Bojana Carić, Nevena Radic, Sanja Medenica, Emilija Manojlovic Gacic, Milan Petakov

“…Majority of lesions were solid on magnetic resonance imaging - MRI (81.25%). Distinct clinical phenotype was observed dependent on the etiology of XG.…”
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Epithelial–Mesenchymal Transition Suppression by ML210 Enhances Gemcitabine Anti-Tumor Effects on PDAC Cells by Keisuke Takemura, Kyohei Ikeda, Hayato Miyake, Yoshio Sogame, Hiroaki Yasuda, Nobuhiro Okada, Kazumi Iwata, Junichi Sakagami, Kanji Yamaguchi, Yoshito Itoh, Atsushi Umemura

“…Since EMT is a major malignant phenotype of PDAC, our findings may lead to the advancement of PDAC therapy, especially in the prevention of postoperative recurrence.…”
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Plasticity of Mesenchymal Stem Cells from Mouse Bone Marrow in the Presence of Conditioned Medium of the Facial Nerve and Fibroblast Growth Factor-2 by Eudes Euler de Souza Lucena, Fausto Pierdoná Guzen, José Rodolfo Lopes de Paiva Cavalcanti, Maria Jocileide de Medeiros Marinho, Wogelsanger Oliveira Pereira, Carlos Augusto Galvão Barboza, Miriam Stela Mariz de Oliveira Costa, Expedito Silva do Nascimento Júnior, Jeferson Sousa Cavalcante

“…Cells cultivated only with conditioned medium acquired a glial phenotype. Cells cultured with FGF-2 and conditioned medium expressed GFAP, OX-42, MAP-2, β-tubulin III, NeuN, and NF-200. …”
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Genetic Analysis and Follow-Up of 25 Neonatal Diabetes Mellitus Patients in China by Bingyan Cao, Chunxiu Gong, Di Wu, Chaoxia Lu, Fang Liu, Xiaojing Liu, Yingxian Zhang, Yi Gu, Zhan Qi, Xiaoqiao Li, Min Liu, Wenjing Li, Chang Su, Xuejun Liang, Mei Feng

“…To study the clinical features, genetic etiology, and the correlation between phenotype and genotype of neonatal diabetes mellitus (NDM) in Chinese patients. …”
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