-
1101
High Prevalence of Candida Yeast in Milk Samples from Cows Suffering from Mastitis in Poland
Published 2012-01-01“…Strains grouped together on the basis of phenotype characteristics differed in restriction fragment profiles. …”
Get full text
Article -
1102
Theoretical aspects of heterosis
Published 2016-09-01“…We discussed some aspects concerning the role of mutation loads in the formation of heterotic phenotype. Also, we gathered a brief account of findings for interpretation of genetic effects due to linkage and non-allelic genes’ interactions that make nuances to analysis of dominance and over-dominance. …”
Get full text
Article -
1103
Analysis of Gene Expression in Cyclooxygenase-2-Overexpressed Human Osteosarcoma Cell Lines
Published 2014-12-01“…These results may provide useful information to elucidate the molecular mechanism of the COX-2-mediated malignant phenotype in osteosarcoma.…”
Get full text
Article -
1104
The Value of Routine Polymerase Chain Reaction Analysis of Intraocular Fluid Specimens in the Diagnosis of Infectious Posterior Uveitis
Published 2013-01-01“…Conclusion. The clinical phenotype alone was unreliable in diagnosing the underlying infectious cause in a quarter of patients in this study. …”
Get full text
Article -
1105
BV/ODV-E26 is a conserved baculoviral inhibitory factor for optimizing viral virulence in lepidopteran hosts
Published 2025-02-01“…However, how bv/odv-e26 fulfills its role in this phenotype remains largely unknown. In this study, we found that the overexpression of BmNPV bv/odv-e26 delayed viral infection in cultured cells and decreased pathogenicity in B. mori larvae. …”
Get full text
Article -
1106
A comprehensive review of mycoviruses infecting the plant pathogenic fungus Rosellinia necatrix
Published 2025-02-01“…This article provides a comprehensive overview of mycoviruses infecting plant pathogenic fungus Rosellinia necatrix causing white root rot, including the prevalence of their occurrence, their taxonomic classification, their genomic organization and structure, impacts on their fungal host in terms of phenotype in general and virulence in particular, and their ecological interactions including transmission. …”
Get full text
Article -
1107
Macrophages in Tumor Microenvironments and the Progression of Tumors
Published 2012-01-01“…In most tumors, the infiltrated macrophages are considered to be of the M2 phenotype, which provides an immunosuppressive microenvironment for tumor growth. …”
Get full text
Article -
1108
BIOSKIN: A Protocol for the Copenhagen Translational Skin Immunology Biobank and Research Programme
Published 2024-02-01“…The clinical examination includes dermatological verification of diagnosis, evaluation of disease severity and detailed information on phenotype. The biological samples include blood and when accessible and relevant, skin biopsies, tape strips and skin swabs. …”
Get full text
Article -
1109
The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells
Published 2012-01-01“…Arg172 mutants of human IDH2—frequently found with similar mutants of cytosolic IDH1 in grade 2 and 3 gliomas, secondary glioblastomas, and acute myeloid leukemia—catalyze reductive carboxylation of 2-oxoglutarate and reduction to D-2-hydroxyglutarate, which strengthens the neoplastic phenotype by competitive inhibition of histone demethylation and 5-methylcytosine hydroxylation, leading to genome-wide histone and DNA methylation alternations. …”
Get full text
Article -
1110
Twist-Induced Epithelial-to-Mesenchymal Transition Confers Specific Metabolic and Mitochondrial Alterations
Published 2025-01-01“…Cells undergo significant epigenetic and phenotypic change during the epithelial-to-mesenchymal transition (EMT), a process observed in development, wound healing, and cancer metastasis. …”
Get full text
Article -
1111
Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application
Published 2017-01-01“…The stem cell niche has been shown to be vital for stem cell survival and function in a number of different physiological systems; therefore, the LDSC niche may have an impact on LDSC phenotype. The role of the LDSC niche on LDSC viability and function will be discussed as well as the therapeutic potential of LDSC niche modulation.…”
Get full text
Article -
1112
Novel, low-cost bioreactor for in vitro electrical stimulation of cardiac cells
Published 2025-02-01“…IntroductionThe successful implantation of laboratory-grown cardiac tissue requires phenotypically mature cardiomyocytes capable of electrophysiological integration with native heart tissue. …”
Get full text
Article -
1113
Genomic exploration of pediatric neurological disorders: a case series
Published 2025-01-01“…We map the association of variants and genes and disease correlation to neuroleptic malignant syndrome, which matches the phenotype to the cases.…”
Get full text
Article -
1114
PRMT1-methylated MSX1 phase separates to control palate development
Published 2025-01-01“…Overall, we reveal the function and regulatory pathway of MSX1 phase separation as a conserved mechanism underlying cleft palate, providing a proof-of-concept example of a phenotype-associated phase separation mechanism associated with craniofacial developmental disorders.…”
Get full text
Article -
1115
The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis
Published 2012-01-01“…Adhesion molecules belonging to the immunoglobulin superfamily (Ig-SF) commonly play a central role in cell-cell adhesion, and a number of these molecules have been associated with cancer progression and a metastatic phenotype. Surprisingly, the contribution of Ig-SF members to metastasis has not received the attention afforded other cell adhesion molecules (CAMs) such as the integrins. …”
Get full text
Article -
1116
A Newborn with Cleft Palate Associated with PTEN Hamartoma Tumor Syndrome
Published 2025-01-01“…Since the correlation between phenotype and genotype is weak, and the penetrance is age-dependent, this poses the question of the appropriate timing of potentially invasive and burdensome examinations for early cancer detection. …”
Get full text
Article -
1117
ABIN1 Inhibits Inflammation through Necroptosis-Dependent Pathway in Ulcerative Colitis
Published 2022-01-01“…Blocking RIPK1 by Nec-1s in vivo and in vitro dramatically alleviated the colitis and cell death which shares the same phenotype with ABIN1 overexpression. Conclusion. Hence, the dysregulation of ABIN1 may relate to the uncontrolled necroptosis and inflammation in UC, and negatively regulate the occurrence and process of ulcerative colitis. …”
Get full text
Article -
1118
Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis
Published 2018-01-01“…These cells possess a stemness phenotype with a self-renewal ability and multipotential differentiation which was considered the reason for the failure of conventional cancer therapies and tumor recurrence. …”
Get full text
Article -
1119
Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
Published 2016-01-01“…Under O2 ASCs retained their proliferative and differentiative capacities, mesenchymal phenotype, and intracellular organelle’ state. ASCs were proinflammatory activated on transcription level that was confirmed by their ability to suppress activation and proliferation of mitogen-stimulated PBMCs. …”
Get full text
Article -
1120
CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures
Published 2024-01-01“…Moreover, we compared the similarities and differences between human and murine uterine T cell phenotype. Together, uterine CD4+T cells and CD8+ cells exhibited a unique mixed signature of T cell dysfunction, activation, and effector function which enabled them to balance strong immune defense against pathogens with tolerance to fetus. …”
Get full text
Article