Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence by Camran R. Nezhat, Tomiko T. Oskotsky, Joshua F. Robinson, Susan J. Fisher, Angie Tsuei, Binya Liu, Juan C. Irwin, Brice Gaudilliere, Marina Sirota, David K. Stevenson, Linda C. Giudice

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GPA-MDS: A Visualization Approach to Investigate Genetic Architecture among Phenotypes Using GWAS Results by Wei Wei, Paula S. Ramos, Kelly J. Hunt, Bethany J. Wolf, Gary Hardiman, Dongjun Chung

“…While GPA provides a statistically rigorous framework to evaluate pleiotropy between phenotypes, it is still not trivial to investigate genetic relationships among a large number of phenotypes using the GPA framework. …”
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Recombinant Chromosome 4 from a Familial Pericentric Inversion: Prenatal and Adulthood Wolf-Hirschhorn Phenotypes by Francesca Malvestiti, Francesco Benedicenti, Simona De Toffol, Sara Chinetti, Adelheid Höller, Beatrice Grimi, Gertrud Fichtel, Monica Braghetto, Cristina Agrati, Eleonora Bonaparte, Federico Maggi, Giuseppe Simoni, Francesca Romana Grati

“…We also describe the adulthood and prenatal phenotypes associated with the recombinant chromosome 4.…”
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Expression of p120-Catenin Isoforms Correlates with Genomic and Transcriptional Phenotype of Breast Cancer Cell Lines by Joana Paredes, Ana Luísa Correia, Ana Sofia Ribeiro, Fernando Schmitt

“…Results: We observed that the expression of p120-catenin isoforms was associated with the genomic and transcriptional phenotype of breast cancer cells. Besides, the recruitment of p120-catenin isoforms was not apparently related with the particular expression of E-, P- or N-cadherin. …”
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Phenotypic Diversity Assessment of Okra (Abelmoschus Esculentus (L.) Moench) Genotypes in Ethiopia Using Multivariate Analysis by Jemal Mohammed, Wassu Mohammed, Eleni Shiferaw

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Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning by D. E. Ivanoshchuk, A. B. Kolker, O. V. Timoshchenko, S. E. Semaev, E. V. Shakhtshneider

“…Variants were identified that may influence the formation of the familial hypercholesterolemia phenotype.…”
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Fructose 1,6-bisphosphatase 1 is a potential biomarker affecting the malignant phenotype and aerobic glycolysis in glioblastoma by Weihong Lu, Guozheng Huang, Yihan Yu, Xia Zhai, Xiangfeng Zhou

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Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation by Donghyun Kang, Jeeyeon Lee, Geunho Yook, Sehan Jeong, Jungkwon Shin, Mi-Sung Kim, Yi-Jun Kim, Hyeryeon Jung, Jinsung Ahn, Tae Woo Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Won Ho Yang, Yong-ho Lee, Jin Won Cho, Eugene C. Yi, Chanhee Kang, Jin-Hong Kim

“…Mechanistically, upregulated O-GlcNAcylation governs the senescence-associated secretory phenotype (SASP) by stabilizing GATA4 via O-GlcNAcylation at S406, which compromises its degradation by p62-mediated selective autophagy. …”
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CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization. by Gowtham A Rao, Azza Shoaibi, Rupa Makadia, Jill Hardin, Joel Swerdel, James Weaver, Erica A Voss, Mitchell M Conover, Stephen Fortin, Anthony G Sena, Chris Knoll, Nigel Hughes, James P Gilbert, Clair Blacketer, Alan Andryc, Frank DeFalco, Anthony Molinaro, Jenna Reps, Martijn J Schuemie, Patrick B Ryan

“…<h4>Objective</h4>This paper introduces a novel framework for evaluating phenotype algorithms (PAs) using the open-source tool, Cohort Diagnostics.…”
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Phenotypic diversity of chickpea (Cicer arietinum L.) landraces accumulated in the Vavilov collection from the centers of the crop origin by M. A. Vishnyаkova, M. O. Burlyaeva, C. B. Bulyntsev, E. V. Seferova, E. S. Plekhanova, S. V. Nuzhdin

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Association between the dietary index for gut microbiota and diabetes: the mediating role of phenotypic age and body mass index by Yingxuan Huang, Xiaobo Liu, Chanchan Lin, Xinqi Chen, Yingyi Li, Yisen Huang, Yubin Wang, Xiaoqiang Liu

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Distinct phenotypes of salivaricin-producing Ligilactobacillus salivarius isolated from the gastrointestinal tract of broiler chickens and laying hens by A.G. Elnar, Y.J. Jang, B.G. Eum, M.H. Kang, G.W. Hwang, D.Y. Kil, G.B. Kim

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An Efflux Pumps Inhibitor Significantly Improved the Antibacterial Activity of Botanicals from Plectranthus glandulosus towards MDR Phenotypes by Gravalain Nanmeni, Alex T. Tedonkeu, Aimé G. Fankam, Armelle T. Mbaveng, Brice E. N. Wamba, Paul Nayim, Gabin T. M. Bitchagno, Raïssa T. Nzogong, Maurice D. Awouafack, Mathieu Tene, Veronique P. Beng, Victor Kuete

“…This study aimed to investigate the antibacterial activity of extract, fractions, and phytochemicals from Plectranthus glandulosus (Lamiaceae) against multidrug-resistant (MDR) Gram-negative phenotypes expressing efflux pumps. The crude extract after extraction was subjected to column chromatography, and the structures of the isolated compounds were determined using spectrometric and spectroscopic techniques. …”
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Ecological niche and phenotypic differences among two alpine Rhododendron species and their natural hybrids in a common landscape by Yanghui Zhao, Ying Zhang, Liang Xu, Yadan Yan, Chuncheng Wang, Yafeng Wen, Donglin Zhang

“…We employed nested linear models, and phenotypic differentiation coefficients to assess inter- and intraspecific phenotypic variation. …”
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Global Phenotypic Characterization of Effects of Fluoroquinolone Resistance Selection on the Metabolic Activities and Drug Susceptibilities of Clostridium perfringens Strains by Miseon Park, Fatemeh Rafii

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Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients by David Nana Adjei, Thomas Stuart Mughogho, Olu-Taiwo Michael, Sarah Saidu, Gloria Amegatcher, Akua Obeng Forson

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Multivariate Analysis of Phenotypic Diversity of Rice (Oryza sativa L.) Landraces from Lamjung and Tanahun Districts, Nepal by Anup Dhakal, Amrit Pokhrel, Shishir Sharma, Ankur Poudel

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Associations between skeletal muscle phenotype, positional role, and on‐ice performance in elite male ice hockey players by Jeppe F. Vigh‐Larsen, Hallur Thorsteinsson, Martin Thomassen, Jeppe Panduro, Bjørn Fristrup, Morten B. Randers, Jens L. Olesen, Peter Krustrup, Kristian Overgaard, Lars Nybo, Magni Mohr

“…Abstract We evaluated associations between muscle phenotype, positional role, and on‐ice performance in male U20 Danish national team ice hockey players. …”
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Zim4rv: an R package to modeling zero-inflated count phenotype on regional-based rare variants by Xiaomin Liu, Yi-Ju Li, Qiao Fan

“…Abstract Background With the advance of next-generation sequencing, various gene-based rare variant association tests have been developed, particularly for binary and continuous phenotypes. In contrast, fewer methods are available for traits not following binomial or normal distributions. …”
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Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

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