-
2341
Quantification and identification of bacterial presence in salted eggs
Published 2025-01-01“…The total bacterial count was determined using the plate count agar method, and bacterial identification was based on phenotypic analysis, which included Gram staining and biochemical tests. …”
Get full text
Article -
2342
Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach
Published 2025-01-01“…Specifically, we demonstrate that prototypical networks can be used to enforce robust performance across domain-informed sub-classes, including different tremor phenotypes and daily life activities.…”
Get full text
Article -
2343
Balancing Inflammation: The Link between Th17 and Regulatory T Cells
Published 2016-01-01“…CD4+ T cell compartments in mouse and man are composed of multiple distinct subsets each possessing unique phenotypic and functional characteristics. IL-17-producing CD4+ T cells (Th17 cells) represent a distinct subset of the CD4+ T cell lineage. …”
Get full text
Article -
2344
Gene by Sex Interaction for Measures of Obesity in the Framingham Heart Study
Published 2011-01-01“…We sought to determine if the effect of genetic variants also differed by sex by performing a genome-wide association study modeling the effect of genotype-by-sex interaction on obesity phenotypes. Genotype data from individuals in the Framingham Heart Study Offspring cohort were analyzed across five exams. …”
Get full text
Article -
2345
Early Social Enrichment Improves Social Motivation and Skills in a Monogenic Mouse Model of Autism, the Oprm1−/− Mouse
Published 2016-01-01“…Environmental enrichment has been proven to have positive effects on both behavioral and physiological phenotypes in rodent models of mental and neurodevelopmental disorders. …”
Get full text
Article -
2346
Targeted correction of megabase-scale CNTN6 duplication in induced pluripotent stem cells and impacts on gene expression
Published 2025-01-01“…However, duplication of the full-length human CNTN6 gene presents with variable penetrance, resulting in phenotypes that range from neurodevelopmental disorders to no visible pathologies, even within the same family. …”
Get full text
Article -
2347
Genome-wide association study unravels mechanisms of brain glymphatic activity
Published 2025-01-01“…Our findings enhance the understanding of the genetics of the ALPS-index and provide insight for further research into the neurobiological mechanisms of glymphatic clearance activity across the lifespan and its relation to neuropsychiatric phenotypes.…”
Get full text
Article -
2348
Inherited Paediatric Motor Neuron Disorders: Beyond Spinal Muscular Atrophy
Published 2017-01-01“…This has reinforced the clinical phenotyping and molecular genetic expertise required to navigate the complexities of such diagnoses. …”
Get full text
Article -
2349
Diversity of TCR repertoire predicts recurrence after CRT followed by durvalumab in patients with NSCLC
Published 2025-01-01“…This prospective study, conducted from November 2019 to May 2021 at three institutions in Japan, evaluated the diversity of TCR repertoire (DE50) in PD-1 + CD8 + T-cells and CD8 + T-cell phenotypes in peripheral blood before and after CRT. …”
Get full text
Article -
2350
MOLECULAR CHARACTERIZATION OF CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE AT A TERTIARY CARE LABORATORY IN KERALA, INDIA
Published 2023-11-01“…Result: The twelve isolates resistant to carbapenem were confirmed phenotypically and were confirmed using a multiplex Polymerase Chain Reaction. …”
Get full text
Article -
2351
Recent advances in adipose-derived mesenchymal stem cell-derived exosomes for regulating macrophage polarization
Published 2025-02-01“…This review summarizes the contents and functions of ADSC-EXOs, outlines their properties and the characteristics of macrophage phenotypes, and emphasizes their impact on macrophage polarization and their contribution to immune-related diseases.…”
Get full text
Article -
2352
COMPARISON OF THE COMPLETE NUCLEOTIDE SEQUENCES OF MITOCHONDRIAL DNA FROM WISTAR AND OXYS RAT STRAINS MAINTAINED AT THE INSTITUTE OF CYTOLOGY AND GENETICS SB RAS
Published 2015-01-01“…It was shown that two additional unique nucleotide substitutions between rats OXYS (ICG) and Wistar (ICG) were absent from other known nucleotide sequences of rat mitochondrial DNA of rats and that they did not cause amino acid substitutions, so that all phenotypic differences between the lines were determined only by differences in their nuclear DNA. …”
Get full text
Article -
2353
Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Published 2025-02-01“…Dietary fat supplementation further boosts sebum production and partially rescues both the lipoatrophy and the aberrant skin phenotypes. The data establish a critical role for cytosolic acetyl-CoA synthesis in maintaining skin barrier integrity and highlight the skin as a key organ in systemic lipid regulation.…”
Get full text
Article -
2354
Strategies Affording Prevascularized Cell-Based Constructs for Myocardial Tissue Engineering
Published 2014-01-01“…To this aim, cells with a differentiation potential towards vascular and cardiac muscle phenotypes have been cocultured in 2D or 3D appropriate scaffolds. …”
Get full text
Article -
2355
Cacao floral traits are shaped by the interaction of flower position with genotype
Published 2025-02-01“…These findings emphasize the phenotypic diversity of cacao flowers and demonstrate the potential of machine learning in genotype identification, offering valuable insights for breeding and cultivation strategies to enhance cacao productivity.…”
Get full text
Article -
2356
NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease
Published 2017-01-01“…The severe glomerular injury and tubulointerstitial fibrosis induced in WT mice by UUO was markedly attenuated in NLRP3−/− mice as evidenced by blockade of extracellular matrix deposition, decreased cell apoptosis, and phenotypic alterations. Moreover, NLRP3 deletion reversed UUO-induced impairment of mitochondrial morphology and function. …”
Get full text
Article -
2357
Single cell suppression profiling of human regulatory T cells
Published 2025-02-01“…Additionally, scSPOT identifies a Treg phenotypic split previously observed in viral infection and propose modes of action by the FDA-approved drugs Ipilimumab and Tazemetostat. scSPOT is thus scalable, robust, widely applicable, and may be used to better understand Treg immunobiology and screen for therapeutic compounds.…”
Get full text
Article -
2358
Differential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus
Published 2016-01-01“…We aimed to figure out whether NP and AF also contain stem cells and whether these stem cells share common properties with chondrocytes and/or fibroblasts in their phenotypes or whether they are completely different types of cells with different characteristics. …”
Get full text
Article -
2359
Comprehensive Genetic Analysis of Edible-Podded Pea Genotypes: Variability, Heritability, and Multivariate Approach Across Two Agro-Climatic Zones in India
Published 2025-01-01“…Significant variation was observed for most traits, with high genotypic and phenotypic coefficients of variation, heritability, and genetic advance, especially in vigor, yield, and biochemical traits. …”
Get full text
Article -
2360
From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
Published 2012-01-01“…While the resulting physiological and behavioral phenotypes vary in their penetrance and severity, all individuals with DS have variable but significant levels of cognitive disability. …”
Get full text
Article