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2321
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration
Published 2012-01-01“…In a recent study, Couthouis et al. screened for protein candidates that were also involved in RNA processing, contained a predicted prion domain, shared other phenotypic similarities with TDP-43 and FUS, and identified TAF15 as a putative ALS gene. …”
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2322
Evidence of the Complexity of Gene Expression Analysis in Fish Wild Populations
Published 2017-01-01“…Although significant, the correlations between gene expression and salinity were slightly ambiguous and did not show any link with phenotypic differences in life history traits previously reported between the same populations. …”
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2323
Mistakes in the diagnosis and treatment of atopic dermatitis
Published 2024-02-01“…It is easy to make mistakes during the diagnosis and treatment of AD due to the complex clinical picture of the disease and the diversity of phenotypes. Obstacles can also be encountered during differential diagnosis. …”
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2324
Growth and Decay of a Planktonic Microbial Culture
Published 2020-01-01“…Deviations of such a trend concern microbes able to form spores, modify their metabolism, or express phenotypic heterogeneity, to counterbalance adverse medium conditions.…”
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2325
State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research
Published 2018-01-01“…However, only minor attempts have been made to connect distinct plastic remodeling processes as causative features for specific behavioral phenotypes. Here, we review current state-of the art techniques for the examination of cortical reorganization and for the manipulation of neuronal circuits as well as techniques which combine anatomical changes with molecular profiling. …”
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2326
African swine fever: one hundred years later
Published 2022-06-01“…In addition to the gaps mentioned in these conclusions and recommendations there are serious gaps in African swine fever immunology, namely in protective immunity mechanisms, virus-macrophage interaction, in vitro virus phenotypic signs correlating with its virulence, etc. …”
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2327
Molecular detection of pore-forming leuko toxin in methicillin resistant Staphylococcus aureus isolated from skin infection
Published 2024-01-01“…Results: All isolates were determined to be resistant to cefoxitin discs and oxacillin by using phenotypic analysis, and a genotypic investigation revealed that 79.16% of them carried the mecA gene. …”
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2328
Role of Helicobacter pylori in the Pathogenesis of Gastric Carcinoma and Progression of Lymphoid Nodules to Lymphoma
Published 1999-01-01“…Investigation of early gastric carcinomas concluded that two main pathways operated in gastric carcinogenesis, both starting from H pylori gastritis and leading to phenotypically variable gastric or intestinal tumour growth. …”
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2329
Effector, Memory, and Dysfunctional CD8+ T Cell Fates in the Antitumor Immune Response
Published 2016-01-01“…These interactions and signals can lead to transcriptional, functional, and phenotypic changes in TILs that diminish the host’s ability to eradicate the tumor. …”
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2330
Emerging Paradigms in Genomics-Based Crop Improvement
Published 2013-01-01“…Furthermore, rapid generation of genome-wide marker data coupled with easy access to precise and accurate phenotypic screens enable large-scale exploitation of LD not only to discover novel QTLs via whole genome association scans but also to practise genomic estimated breeding value (GEBV)-based selection of genotypes. …”
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2331
METHODS OF CHOOSING PARENTAL PAIRS FOR CROSSES IN THE BREEDING OF SELF-POLLINATING CROPS FOR YIELD
Published 2018-06-01“…Meanwhile, as a result of extensive exchange of breeding material, this ecogeographical approach to the matching of pairs has lost its relevance, being replaced by the new methods of finding phenotypic and genotypic differences between parents. …”
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2332
Non-metric variations in individuals who died during the perinatal period in past populations: recording protocol and comparative data
Published 2023-08-01“…Non-metric variations, also referred to as "epigenetic variations" or asymptomatic bone variants, are bone or dental phenotypic variants of unknown origin, with no known pathological etiology. …”
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2333
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2334
Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan...
Published 2025-02-01“…This study assessed the proportion of laboratory-confirmed SSTIs, identify bacterial species involved, analyze AMR phenotypes, and investigate the risk factors associated with multidrug-resistant (MDR) SSTIs.Patients and Methods: Analytical cross-sectional study was conducted between January and June 2023, involving 614 patients with SSTIs. …”
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2335
A Maternal Loss‐of‐Function Variant in KHDC3L Gene Causes a Range of Adverse Pregnancy Outcomes: A Case Report
Published 2025-01-01“…This case report broadens the understanding of KHDC3L's pathogenic variants and phenotypic spectrum, consistent with its crucial role during human pre‐ and post‐implantation development.…”
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2336
Genetic variability, heritability and genetic advance in chrysanthemum (Dendranthema grandiflora) genotypes evaluated for loose flower production
Published 2024-12-01“…Analysis of variance exhibited noteworthy variation in the genetic potential of the genotypes for every trait under study. The magnitude of phenotypic coefficient of variation (PCV) for each trait was discovered to be higher than the genotypic coefficient of variation (GCV), which demonstrated an interaction between the genotype and environment. …”
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2337
Oncogenic role of RARG rearrangements in acute myeloid leukemia resembling acute promyelocytic leukemia
Published 2025-01-01“…RARG fusions overexpression leads to preleukemic phenotypes but fails to induce oncogenic transformation. …”
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2338
A Case of Chemotherapy-Refractory “THRLBCL like Transformation of NLPHL” Successfully Treated with Lenalidomide
Published 2018-01-01“…The two major differences are the background cell type and the morphologic pattern. Despite having a phenotypic resemblance, they have distinct biologic behavior and clinical course. …”
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2339
Atypical Features in a Large Turkish Family Affected with Friedreich Ataxia
Published 2016-01-01“…Description of FRDA families with different ethnic backgrounds may assist in identifying possible phenotypic and genetic features of the disease. Furthermore, the genetic heterogeneity observed in this family draws attention to the difficulty of genetic counseling in an inbred population and to the need for genotyping all affected members before delivering comprehensive genetic counseling.…”
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2340
Gemistocytic tumor cells programmed for glial scarring characterize T cell confinement in IDH-mutant astrocytoma
Published 2025-01-01“…Abstract Isocitrate dehydrogenase 1/2 mutant (IDHmt) astrocytoma is considered a T cell-deprived tumor, yet little is known regarding the phenotypes underlying T cell exclusion. Using bulk, single nucleus and spatial RNA and protein profiling, we demonstrate that a distinct spatial organization underlies T cell confinement to the perivascular space (T cell cuff) in IDHmt astrocytoma. …”
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