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2181
Innate Immune Responses Associated with Resistance against Haemonchus contortus in Morada Nova Sheep
Published 2019-01-01“…The present study is aimed at evaluating mediators from the innate immune response in lambs of the Morada Nova Brazilian breed with contrasting H. contortus resistance phenotypes. Briefly, 287 lambs were characterized through fecal egg counts (FEC) and packed cell volume (PCV) after two independent experimental parasitic challenges with 4,000 H. contortus L3. 20 extreme resistance phenotypes (10 most resistant and 10 most susceptible) were selected, subjected to a third artificial infection with 4,000 L3, and euthanized 7 days later. …”
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2182
Frequency of remission achievement in the pre-treat-to-target decade in juvenile idiopathic arthritis
Published 2025-01-01“…Patients were classified into four “functional phenotypes”: systemic arthritis (7.1%), oligoarthritis (48.2%), polyarthritis (40.4%), and other arthritis (4.3%). …”
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2183
Comparative transcriptomic analysis and identification of candidate genes related to Verticillium wilt resistance in Gossypium barbadense and Gossypium hirsutum
Published 2025-03-01“…Phenotypic evaluation revealed that, compared with TM-1, Hai7124 was more resistant to Verticillium wilt. …”
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2184
Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia
Published 2005-12-01“…Based on genetic and nutritional studies the best way for expression of healthier phenotypes should be found and used to promote health and prevent different diseases development.…”
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2185
Vitamin D Binding Protein and Bone Health
Published 2014-01-01“…Several genetic polymorphisms of DBP have been described that lead to phenotypic changes in the protein that may affect affinity, activity, and concentration. …”
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2186
Corneal Stem Cells as a Source of Regenerative Cell-Based Therapy
Published 2020-01-01“…This review describes in detail phenotypic characteristics of LESCs and CSSCs and discusses their therapeutic potential in corneal regeneration. …”
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2187
A Mathematical Model for DNA Damage and Repair
Published 2010-01-01“…The model allows us to examine the effect of phenotypic and genotypic factors such as different concentrations of estrogen and variant enzyme haplotypes on the formation and repair of DNA adducts.…”
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2188
Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy
Published 2012-01-01“…Furthermore, senescent BECs may modulate the microenvironment around bile ducts by expressing various chemokines and cytokines called senescence-associated secretory phenotypes and contribute to the pathogenesis in PBC.…”
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2189
Sensibilisation à l’environnement d’un collège alsacien et d’une école malgache
Published 2015-12-01“…Three annual visits to the zoo allow to children (1) to enhance their understanding of the fauna and flora, this aspect being completed by a personal bibliography produced by children; (2) to introduce notions on the phenotypic classification of primates by observing animals and the help of simple arrays of determining criteria ; (3) to improve their ecological awareness with tangible and common examples like the deforestation in Madagascar or the invasive species introduction, pupils are invited to think about these subjects and to suggest theoretical solutions ; (4) to observe the interspecific behavioral differences and the sexual hierarchy of lemurs using simple ethological observations ("all occurrences sampling" methods) of several species.…”
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2190
Aspergillus section Versicolores: nine new species and multilocus DNA sequence based phylogeny
Published 2012-06-01“…Aspergillus austroafricanus, A. creber, A. cvjetkovicii, A. fructus, A. jensenii, A. puulaauensis, A. subversicolor, A. tennesseensis and A. venenatus are described as new species and A. amoenus, A. protuberus, A. sydowii, A. tabacinus and A. versicolor are accepted as distinct species on the basis of molecular and phenotypic differences. PCR primer pairs used to detect A. versicolor in sick building syndrome studies have a positive reaction for all of the newly described species except A. subversicolor.…”
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2191
CNTNAP1 Mutations and Their Clinical Presentations: New Case Report and Systematic Review
Published 2020-01-01“…Recent studies have shown that both diseases could present with a wide phenotypic spectrum, with promising survival up to early childhood. …”
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2192
Persistent Müllerian Duct Syndrome: Understanding the Challenges
Published 2022-01-01“…Persistent Müllerian duct syndrome (PMDS) is a rare autosomal recessive condition defined by the presence of Müllerian duct-derived structures in an otherwise normally masculinized phenotypical and genotypical (46,XY) male. We describe the case of an infant diagnosed with PMDS, managed and followed up for 7 years. …”
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2193
Management of Climatic Factors for Successful Silkworm (Bombyx mori L.) Crop and Higher Silk Production: A Review
Published 2012-01-01“…The seasonal differences in the environmental components considerably affect the genotypic expression in the form of phenotypic output of silkworm crop such as cocoon weight, shell weight, and cocoon shell ratio. …”
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2194
Acute Aortic Dissection in Pregnancy in a Woman with Undiagnosed Marfan Syndrome
Published 2012-01-01“…On later examination, our patient fulfilled the diagnostic criteria for phenotypic expression of Marfan syndrome. Genetic testing also confirmed that she has a mutation of the fibrillin (FBN 1) gene associated with the disease.…”
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2195
Genome rearrangements in neurodevelopmental disorders of the central nervous system: origins, genomic mechanisms, functional and clinical consequences. Review article
Published 2022-03-01“…Reasearch into the genetic causes of intellectual disability is challenging because these conditions are genetically heterogeneous with many different genetic alterations resulting in clinically indistinguishable phenotypes. Extensive molecular technologies are being used in research to determine the genetic causes of these conditions. …”
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2196
Generation and Characterization of Erythroid Cells from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells: An Overview
Published 2011-01-01“…Because of the imbalance in the supply and demand of red blood cells (RBCs), especially for alloimmunized patients or patients with rare blood phenotypes, extensive research has been done to generate therapeutic quantities of mature RBCs from hematopoietic stem cells of various sources, such as bone marrow, peripheral blood, and cord blood. …”
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2197
Fully automated in vivo screening system for multi-organ imaging and pharmaceutical evaluation
Published 2025-01-01“…However, current strategies for phenotyping of behaving animals, such as zebrafish, typically involve tedious manipulations. …”
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2198
Epidemiological Profile of Patients with Cutaneous Melanoma in a Region of Southern Brazil
Published 2012-01-01“…This fact is most likely due to the phenotypic characteristics of the population and the high incidence of UV radiation in this region due to its location in southern Brazil, as is the case in the countries of Oceania.…”
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2199
Vitreous Analysis in the Management of Uveitis
Published 2012-01-01“…A correct diagnosis of uveitis is often challenging, given the wide range of possible underlying conditions and the lack of typical phenotypes. Management decisions may be difficult in view of the risk of visual loss with either inappropriate or delayed therapy. …”
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2200
Effect of Water Velocity on the Timing of Skeletogenesis in the Arctic Charr, Salvelinus alpinus (Salmoniformes: Teleostei): An Empirical Case of Developmental Plasticity
Published 2010-01-01“…Phenotypic plasticity has been demonstrated in fishes but rarely addressed with respect to skeletogenesis. …”
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