The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…Yinshuang Zou,1– 3,* Yaji Yang,1,3,* Jianye Yang,1,3 Yanhao Zhang,4 Chen Zhao,1,3 Leilei Qin,1,3 Ning Hu1,3 1Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Orthopedics, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, 434000, People’s Republic of China; 3Laboratory of Orthopedics, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Army Medical University, Chongqing, 400038, People’s Republic of China*These authors contributed equally to this workCorrespondence: Leilei Qin; Ning Hu, Email qinleilei@stu.cqmu.edu.cn; huning@cqmu.edu.cnBackground: Diagnosing chronic periprosthetic joint infection (PJI) is challenging. …”
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Mitigating bias in AI mortality predictions for minority populations: a transfer learning approach by Tianshu Gu, Wensen Pan, Jing Yu, Guang Ji, Xia Meng, Yongjun Wang, Minghui Li

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Potential effects of induced focal ischemia in the motor cortex of rats undergoing experimental periodontitis by Victória dos Santos Chemelo, Marco Aurelio M. Freire, Leonardo Oliveira Bittencourt, Deborah Ribeiro Frazão, Deiweson Souza-Monteiro, Sabrina C. Cartagenes, Walace Gomes-Leal, Cristiane do Socorro Ferraz Maia, Gabriel S. Rocha, Daniel Falcao, Rafael Rodrigues Lima

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Effects of the New Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m on High Glucose Induced Prolongation of Cardiac QT Interval and Increase of Coronary Perfusion Pressure by C. Di Filippo, B. Ferraro, R. Maisto, M. C. Trotta, N. Di Carluccio, S. Sartini, C. La Motta, F. Ferraraccio, F. Rossi, M. D’Amico

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Development and Characterization of a Hydrogel Containing Chloramphenicol-Loaded Binary Ethosomes for Effective Transdermal Permeation and Treatment Acne in Rat Model by Liu RJ, Li M, Zhu Q, Liu HY, Zhang XX, Han XY, Yu MJ, Zhou JW, Han CY

“…Run jia Liu,1 Miao Li,1 Qian Zhu,1 Hui ying Liu,1 Xing xiu Zhang,1 Xiang yuan Han,1 Meng jun Yu,1 Jian wen Zhou,2 Cui yan Han1 1School of Pharmacy, Qiqihar Medical University, Qiqihar, People’s Republic of China; 2Institute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, People’s Republic of ChinaCorrespondence: Cui yan Han, School of Pharmacy, Qiqihar Medical University, Qiqihar, People’s Republic of China, Tel/Fax +86-24-2663822, Email hcymuphar@qmu.edu.cnPurpose: Acne is a serious disfiguring follicular sebaceous gland disorder that negatively affects patients’ quality of life and self-image. …”
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Evaluation of a user‐friendly CSDS cage apparatus for studying depressive‐like behaviors in rodents by Hao Zhang, Dongmei Gao, Minghu Hu, Wanqing Zhou, Muxuan Han, Ya Sun, Yang Zhang, Jieqiong Wang, Mingzhou Gao

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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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Targeting Cutaneous Leishmaniasis with Thiadiazine Thione Derivatives: An In Vivo Study of Its Anti-Inflammatory, Anti-Pyretic, Anti-Nociceptive, and Anti-Sedative Properties by Sarah Sarwar, Nadia Sarwar, Haleema Ali, Rafiullah, Rasool Khan, Ajaz Ahmad, Amin Ullah, Ho Soonmin, Nazif Ullah

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The safety and effectiveness of tDCS for epileptic patients: A systematic review and meta-analysis by Xiao-Tong Ding, Ming-Yu Hu, Chi Wang, Wei-Ye Kang, Jin-Zhao Huang, Rui-Yu Wang, Qiu-Song Shen, Hou-Ming Kan

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Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedi... by Marie C. Hyslop, Diana E. Papaioannou, Robert Bolt, Matthew J. Wilson, Michael Bradburn, Janet Clarkson, Esther Herbert, Nicholas Ireland, Jennifer Kettle, Amanda Loban, Amy C. Norrington, Christopher Vernazza, Christopher Deery

“…Future paediatric perioperative medicine trials could consider funding for research pharmacy outside of working hours; conducting risk assessments for study drugs to be held on theatre admission units; and a tailored design of site feasibility assessments to help address variation in practice. …”
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Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4 by Asma Khatoon Zaidi, Anurag Kumar, Rohit Kumar, Jyoti Singh, Sneha Yadav, Archana Bharti Sonkar, Dharmendra Kumar, Neeraj Kumar Shrivastava, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas

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Canine and Human Dirofilariosis in the Rostov Region (Southern Russia) by Vladimir Kartashev, Irina Batashova, Sergey Kartashov, Alexey Ermakov, Anna Mironova, Yulia Kuleshova, Boris Ilyasov, Irina Kolodiy, Alexander Klyuchnikov, Elena Ryabikina, Marina Babicheva, Yulia Levchenko, Raisa Pavlova, Nicola Pantchev, Rodrigo Morchón, Fernando Simón

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Differences in Metabolites of Different Varieties from Xinjiang Large-fruit Sea Buckthorn as Analyzed by Non-targeted Metabolomics by Rong HAN, Yan MA, Shengjie LI, Xintao MENG, Mingqiang XU, Ting ZHANG, Yan PAN

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Determination of the Contents of Antioxidants and Their Degradation Products in Sodium Chloride Injection for Blood Transfusion by Bo Tao, Gang Wang, Zongning Yin, Xiaocong Pu, Yan Jiang, Luohong Zhang, Jie Cheng, Yong Li, Jiayu Zhang

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Ultrasonic and Microwave-assisted Solid-Liquid Extraction of Ginkgo biloba Phenolics: Study about Mass Transfer and PID Control by Chi XU, Hebin XU, Rui ZHU, Jing LI, Dandan LI, Yongbin HAN, Yi ZHENG, Yang TAO

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Cdk6’s functions are critically regulated by its unique C-terminus by Alessia Schirripa, Helge Schöppe, Sofie Nebenfuehr, Markus Zojer, Thorsten Klampfl, Valentina Kugler, Belinda S. Maw, Huriye Ceylan, Iris Z. Uras, Lisa Scheiblecker, Elisabeth Gamper, Ulrich Stelzl, Eduard Stefan, Teresa Kaserer, Veronika Sexl, Karoline Kollmann

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Knowledge, attitudes, and practices toward leishmaniasis and one health: a cross-sectional study among medical and veterinary professionals by Yasir Khan, I-Chen Lin, Sundus Khan, Mehtab Kanwal, Abdul Wajid, Aamir Khan, Fazal Noor, Ali Madi Almajwal, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdul Qadeer

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The Clinical and Economic Impact of Employees Who Are Care Partners of Patients with Multiple Sclerosis by Disease Severity by Barry Hendin, Richard A. Brook, Ian A. Beren, Nathan Kleinman, Cindy Fink, Amy L. Phillips, Carroline Lobo

“…Adjusted mean medical costs were greater for employee care partners of patients with moderate vs mild/severe disease (_P_<.001). Pharmacy costs (SE) were lower for employee care partners of mild vs severe/moderate patients (_P_<.005). …”
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Efficacy of Anakinra for Various Types of Crystal-Induced Arthritis in Complex Hospitalized Patients: A Case Series and Review of the Literature by A. Aouba, S. Deshayes, L. Frenzel, A. Decottignies, C. Pressiat, B. Bienvenu, F. Boue, G. Damaj, O. Hermine, S. Georgin-Lavialle

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Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwellin... by Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Caroline McCarthy, Ann Sinéad Doherty, Mark Feighery

“…Objectives To describe the prevalence of sub-optimal monitoring for selected higher-risk medicines in older community-dwelling adults and to evaluate patient characteristics and outcomes associated with sub-optimal monitoring.Study design Retrospective observational study (2011–2015) using historical general practice-based cohort data and linked dispensing data from a national pharmacy claims database.Setting Irish primary care.Participants 625 community-dwelling adults aged ≥70 years and prescribed at least one higher-risk medicine during the 5-year study period.Primary and secondary outcome measures The primary outcome was the prevalence of sub-optimal laboratory monitoring using a composite measure of published medication monitoring indicators, with a focus on commonly prescribed higher-risk medicines such as diuretics and anticoagulants. …”
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