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321
Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents
Published 2025-03-01Subjects: Get full text
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322
The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities
Published 2025-01-01“…Specifically, comparative studies could be key to identifying species with unique chemical profiles and understanding how variations in secondary metabolite composition may influence their pharmacological activities. This work highlights the urgent need to expand research in these areas to validate the pharmacological properties of <i>Chiliadenus</i> species for their application in modern medicine.…”
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Characterization of the Active Ingredient and Prediction of the Potential Mechanism of Dahuoluo Pill via Mass Spectrometry with the Network Pharmacology Method
Published 2023-01-01“…We then used network pharmacology to predict the underlying mechanisms by which DHLP ameliorates rheumatoid arthritis. …”
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325
Neural mechanisms of non-pharmacological interventions in patients with mild cognitive impairment and Alzheimer's disease: An ALE meta-analysis
Published 2025-02-01Subjects: Get full text
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326
Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm
Published 2025-02-01“…Aim of the study: The aim of this study was to systematically investigate the effects and mechanisms of Rhubarb in the treatment of Atherosclerosis (AS) and Abdominal Aortic Aneurysm (AAA) by utilizing network pharmacology and molecular docking techniques. Materials and methods: TCMSP systematic pharmacology database was utilized to search for active chemical components of Rhubarb. …”
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327
Effects of pharmacologic sclerostin inhibition or testosterone administration on soleus muscle atrophy in rodents after spinal cord injury.
Published 2018-01-01“…Sclerostin is a circulating osteocyte-derived glycoprotein that negatively regulates Wnt-signaling after binding the LRP5/LRP6 co-receptors. Pharmacologic sclerostin inhibition produces bone anabolic effects after spinal cord injury (SCI), however, the effects of sclerostin-antibody (Scl-Ab) on muscle morphology remain unknown. …”
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328
Pharmacological correction of post-contrast acute kidney injury with a functional product based on fermented grape juice
Published 2024-12-01“…Research Results in Pharmacology…”
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Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma
Published 2021-01-01“…Taken together, this study revealed the potential drug targets and underlying mechanisms of polyphyllin II against NPC through modern network pharmacology, which provided a certain theoretical basis for the future nano TCM research.…”
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332
Synthesis and pharmacological properties of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione
Published 2024-09-01“…Research Results in Pharmacology…”
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Scoping review protocol on non-pharmacological interventions for interpersonal and self-directed violence in adults with severe mental illness
Published 2020-09-01“…Several strategies to reduce the risk of aggressive and violent behaviour have been proposed, and these include non-pharmacological interventions. There is, however, a need to identify which of these interventions are effective, and as a first step, we will conduct a scoping review to identify non-pharmacological interventions for self-directed or interpersonal violence in adults with severe mental illness across different conditions and settings.Methods and analysis This is a scoping review protocol. …”
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335
Shenlian Decoction Ameliorates LPS-Related Inflammation in db/db Mice: Coupling Network Pharmacology With Experimental Verification
Published 2025-01-01“…Conclusions: This research investigated the multigene pharmacological mechanism of SL decoction against T2DM using network pharmacology and in vivo experiments. …”
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336
Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model
Published 2020-05-01“…Data obtained demonstrate that recombinant TNF-BD protein is pharmacologically active in the experimental model of LPS-induced septic shock.…”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant
Published 2024-01-01“…Despite numerous studies demonstrating various pharmacological advantages of this plant and its constituents, the number of clinical trials conducted on humans remains significantly limited.…”
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Bioactive Molecules, Ethnomedicinal Uses, Toxicology, and Pharmacology of <i>Peltophorum africanum</i> Sond (Fabaceae): Systematic Review
Published 2025-01-01“…The plant species possess very important pharmacological activities in vitro, which includes antimicrobial, anti-HIV, antioxidant, anticancer, antidiabetic, and other activities. …”
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340
An updated network meta-analysis of non-pharmacological interventions for primary hypertension in adults: insights from recent studies
Published 2024-12-01Subjects: “…Non-pharmacological interventions…”
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