The Use of Spreadsheets for Pharmacokinetic Simulations by Joseph Chamberlain

“…The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. …”
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Population Pharmacokinetics of Vancomycin in Thai Patients by Tunggul Adi Purwonugroho, Suvatna Chulavatnatol, Yupaporn Preechagoon, Busba Chindavijak, Kumthorn Malathum, Pakwan Bunuparadah

“…Population pharmacokinetics of vancomycin in Thai adult patients was determined by non-linear mixed-effects approach using 319 vancomycin serum concentrations from 212 patients. …”
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Prednisolone pharmacokinetics in dogs with protein‐losing enteropathy by Sara A. Jablonski, Jessica L. Strohmeyer, John P. Buchweitz, Andreas F. Lehner, Daniel K. Langlois

“…Objective To compare pharmacokinetics (PK) of orally administered prednisolone in dogs with PLE vs healthy controls. …”
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Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients by Peng Zou, Akhilesh Atluri, Peter Chang, Michael Goedecke, Tarek A. Leil

“…Abstract Edoxaban is an orally active inhibitor of activated factor X (FXa). Population pharmacokinetic (PK) and pharmacodynamic (PD) analyses were performed to characterize the PK and PK–PD relationships of edoxaban in pediatric patients to identify the covariates that may contribute to inter‐subject variability in PK and PD of edoxaban in pediatric patients, and to compare the PK and PD data between pediatric and adult patients. …”
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Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats by Xiaohan Cao, Zhiyong Chen, Zhuoran Yu, Yonghong Ge, Xianyin Zeng

“…Due to its short half-life, the main aim for this pharmacokinetic study is to investigate a newly developed PEG-rHuEPO with large molecular weight in SD rats. …”
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Pharmacokinetics of Anti-Epileptic Drugs and their Clinical Significance by Svein I. Johannessen

“…OXC seems to lack several disadavantageous pharmacokinetic properties common to other major anti-epileptic drugs. …”
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Pharmacokinetics and Biodistribution of Zinc-Enriched Yeast in Rats by Shuangqing Zhang, Yan Zhang, Ning Peng, Haibo Zhang, Juan Yao, Zhihong Li, Liegang Liu

“…The purpose of the investigation was to compare and evaluate pharmacokinetics and biodistribution of ZnY and ZnSO4 in rats. …”
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Pharmacokinetic Interactions between Cardiovascular Medicines and Plant Products by Irina-Iuliana Costache, Anca Miron, Monica Hăncianu, Viviana Aursulesei, Alexandru Dan Costache, Ana Clara Aprotosoaie

“…Numerous studies and case reports showed various pharmacokinetic interactions that are characterized by a high degree of unpredictability. …”
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Pharmacokinetics of Hyperthermic Intrathoracic Chemotherapy following Pleurectomy and Decortication by Paul H. Sugarbaker, O. Anthony Stuart, Christopher Eger

“…We monitored the intrapleural and plasma levels of mitomycin C and doxorubicin by HPLC assay in order to determine the pharmacokinetic behavior of this intracavitary use of chemotherapy. …”
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Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia by Mihoko Kawai, Ryosuke Aratake, Tadashi Ogawa

“…Managing schizophrenia during pregnancy poses unique challenges due to the potential effects of second‐generation antipsychotics on maternal mental health and fetal development and changes in drug pharmacokinetics. Evidence on how physiological changes during pregnancy affect the levels of second‐generation antipsychotics, particularly lurasidone, is limited. …”
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Pharmacokinetic comparisons of S-oxiracetam and R-oxiracetam in beagle dogs by Wang Wusan, Ji Hui, Li Tingting, Jia Yuanwei, Xie Haitang

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Variation in human gut microbiota impacts tamoxifen pharmacokinetics by Yasmine Alam, Sheron Hakopian, Lizett Ortiz de Ora, Ian Tamburini, Julio Avelar-Barragan, Sunhee Jung, Zane Long, Alina Chao, Katrine Whiteson, Cholsoon Jang, Elizabeth Bess

“…Here, using gnotobiotic- and antibiotics-treated mice, we show that tamoxifen pharmacokinetics are heavily influenced by gut bacteria and prolonged exposure to tamoxifen. …”
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Data-based regression models for predicting remifentanil pharmacokinetics by Prathvi Shenoy, Mahadev Rao, Shreesha Chokkadi, Sushma Bhatnagar, Naveen Salins

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Clinical Pharmacokinetics of Atogepant in Healthy Japanese and White Adults by Ramesh R. Boinpally, Brian McNamee

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A physiologically-based pharmacokinetic model for the antibiotic ertapenem by Michele L. Joyner, Cammey C. Manning, Whitney Forbes, Michelle Maiden, Ariel N. Nikas

Subjects: “…physiologically based pharmacokinetic model (pbpk)…”
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Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment by Michael D. Taylor, Harvey J. Clewell, Melvin E. Andersen, Jeffry D. Schroeter, Miyoung Yoon, Athena M. Keene, David C. Dorman

“…Recently, a variety of physiologically based pharmacokinetic (PBPK) models have been developed for the essential element manganese. …”
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Isoniazid urine spectrophotometry for prediction of serum pharmacokinetics in adults with TB by P. S. Rao, K. Reed, N. Modi, D. Handler, K. Petros de Guex, S. Yu, L. Kagan, R. Reiss, N. Narayanan, C. A. Peloquin, A. Lardizabal, C. Vinnard, T. A. Thomas, Y. L. Xie, S. K. Heysell

“…BACKGROUND: Isoniazid (INH) is an important drug in many TB regimens, and unfavorable treatment outcomes can be caused by suboptimal pharmacokinetics. Dose adjustment can be personalized by measuring peak serum concentrations; however, the process involves cold-chain preservation and laboratory techniques such as liquid chromatography (LC)/mass spectrometry (MS), which are unavailable in many high-burden settings. …”
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Analysis of HIV therapy in the liver using optimal control and pharmacokinetics by Hasifa Nampala, Matylda Jabłońska-Sabuka, Martin Singull

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Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients by Xiaowen Guo, Yang Qiao, Sijie Yin, Fengqin Luo, Lingmei Yi, Jiajia Chen, Man Lu

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