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81
In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems
Published 2025-02-01“…Recognition of this need by the pharmaceutical industry has provided a motivation for research into the development of reliable complex models for use in drug delivery, biomaterials, and tissue engineering. …”
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82
Advances in the biosynthesis of naturally occurring benzylisoquinoline alkaloids
Published 2025-01-01“…Thus, a major obstacle in developing and utilizing these natural products in the pharmaceutical industry lies in their low abundance in nature. …”
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83
Charge heterogeneity of therapeutic monoclonal antibodies by different cIEF systems: views on the current situation
Published 2024-12-01“…These data suggest that the results are method-dependent rather than absolute, an aspect known to experts in the field and pharmaceutical industry, but not suitably documented in the literature. …”
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84
Beyond boundaries: Charting the frontier of healthcare with big data and ai advancements in pharmacovigilance
Published 2025-03-01“…The contemporary trend of Big Data Analytics is pivotal, impacting not only the pharmaceutical industry but also transforming healthcare, contributing to personalized treatment, aiding in preventive healthcare, managing electronic health records, facilitating adverse drug reporting, and incorporating consumer reviews. …”
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85
Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
Published 2022-09-01“…To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. Pharmaceutical industry is investigating effects of medicinal plants, phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs. …”
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86
Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids
Published 2025-01-01“…This work opens avenues for further research and applications in biological monitoring, environmental testing, and the pharmaceutical industry.…”
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87
GC-MS Analysis of Bioactive Compounds in Methanolic Extracts of Papaver decaisnei and Determination of Its Antioxidants and Anticancer Activities
Published 2022-01-01“…The detected alkaloids and bioactivity of P. decaisnei encourage future isolation of those remarkable alkaloids (reomerine) for potential usage in the pharmaceutical industry.…”
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88
Site Saturation Mutagenesis Applications on Candida methylica Formate Dehydrogenase
Published 2016-01-01“…In NADH regeneration, Candida methylica formate dehydrogenase (cmFDH) is a highly significant enzyme in pharmaceutical industry. In this work, site saturation mutagenesis (SSM) which is a combination of both rational design and directed evolution approaches is applied to alter the coenzyme specificity of NAD+-dependent cmFDH from NAD+ to NADP+ and increase its thermostability. …”
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89
Patient Perspectives on Health Data Privacy and Management: “Where Is My Data and Whose Is It?”
Published 2018-01-01“…Patients indicated that they do not want to share their medical data with health insurance companies or the pharmaceutical industry. Furthermore, most patients do not see the added value of supplementing their medical dossier with lifestyle data. …”
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90
Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of Ange...
Published 2020-01-01“…The results also suggested that ultrafine powderization and HME may be developed and applied in the pharmaceutical industry.…”
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91
Sustainable Corrosion Inhibitors from Pharmaceutical Wastes: Advancing Energy-Efficient Chemistry with Green Solutions
Published 2025-01-01“…Pharmaceutical waste is a type of bio-waste inevitably generated by the pharmaceutical industry, often due to regulatory changes, product deterioration, or expiration. …”
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92
Preparation of astaxanthin/zeaxanthin-loaded nanostructured lipid carriers for enhanced bioavailability: Characterization-, stability-and permeability study
Published 2023-12-01“…This study provides useful data about the advantages of using NLC as a delivery system for ASTA and ZEA that might facilitate their applications in the food and pharmaceutical industry.…”
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93
Quality by Design-Based Methodology for Development of Titanate Nanotubes Specified for Pharmaceutical Applications Based on Risk Assessment and Artificial Neural Network Modeling
Published 2025-01-01“…Their implementation in pharmaceutical applications is of huge interest nowadays as it could be of fundamental importance in the development of the pharmaceutical industry and therapeutic systems. Methods: In the present work, a risk assessment-based procedure was developed and completed using ANN-based modeling to enable the design and fabrication of titanate nanotube-based drug delivery systems with desired properties, based on the critical analysis and evaluation of data collected from published articles regarding titanate nanotube preparation using the hydrothermal treatment method. …”
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94
In-situ biophysical characterization of high-concentration protein formulations using wNMR
Published 2024-12-01“…Importantly, these results show a strong correlation with data obtained from established biophysical analytical tools widely used in the pharmaceutical industry. The application of wNMR represents a promising approach for in situ noninvasive analysis of high-concentration protein formulations directly in their primary containers, providing valuable insights for drug development and quality assessment.…”
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95
Sustainable cultivation of phytopharmaceuticals in Baden-Wuerttemberg, Germany: a SWOT analysis and future directions
Published 2025-01-01“…Conversely, six other plants were deemed less viable due to various challenges, including market competition and harvesting difficulties.Conclusions This publication emphasizes the importance of comprehensive planning and analysis in transitioning from wild collection to sustainable cultivation of medicinal plants, highlighting the potential benefits for regional agriculture, conservation efforts, and the pharmaceutical industry. BIOPRO Baden-Württemberg GmbH promotes this approach by fostering a bioeconomy centred on cultivating high-value medicinal plants in the state of Baden-Wuerttemberg, Germany.…”
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96
Enhancing drug discovery and patient care through advanced analytics with the power of NLP and machine learning in pharmaceutical data interpretation
Published 2025-04-01“…This study delves into the transformative potential of Machine Learning (ML) and Natural Language Processing (NLP) within the pharmaceutical industry, spotlighting their significant impact on enhancing medical research methodologies and optimizing healthcare service delivery. …”
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97
Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects
Published 2025-01-01“…With the development of the pharmaceutical industry, there is a gradual desire to develop low-toxicity and effective anticancer drugs from traditional Chinese herbs. …”
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98
A comprehensive review on nutritional composition, health benefits, and industrial applications of Jackfruit Seeds
Published 2025-03-01“…Furthermore, starch extracted from discarded jackfruit seeds can be utilized as thickeners, gelling agents and fillers meanwhile its potential applications in the pharmaceutical industry. So this review emphasizes the nutritional composition, antinutritional factors and health benefits of jackfruit with related applications for product formulations. …”
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99
Significance, pharmacological properties, and industrial applications of bael (Aegle marmelos): A review of current knowledge
Published 2025-03-01“…One way to replicate the therapeutic capabilities of Bael across a wide range of illnesses in the pharmaceutical industry is to formulate bioactive compounds derived from Bael extracts and compounds into medicines for the treatment of diabetes, gastrointestinal problems, or skin ailments. …”
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100
How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis
Published 2022-07-01“…Objectives Pharmaceutical industry involvement in medical education, research and clinical practice can lead to conflicts of interest. …”
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