Effectiveness of PK-Guided Personalized Recombinant FVIII Treatment in Patients with Hemophilia A: Clinical Case Experiences Based on an Observational Study by Mizoguchi Y, Hino M, Ueda H, Miyaguchi Y, Kobayashi M

“…Yoko Mizoguchi,1 Moeko Hino,2 Hitoshi Ueda,3 Yasuo Miyaguchi,3 Masao Kobayashi1,4 1Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan; 2Department of Pediatrics, Chiba University Hospital, Chiba, Japan; 3Japan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, Japan; 4Japanese Red Cross, Chugoku-Shikoku Block Blood Center, Hiroshima, JapanCorrespondence: Yasuo Miyaguchi, Japan Medical Office, Takeda Pharmaceutical Company Limited, 2 Chome-1-1 Nihonbashihoncho, Chuo-ku, Tokyo, 103-0023, Japan, Tel +81 70-4921-7966, Email yasuo.miyaguchi1@takeda.comPurpose: Prophylaxis with recombinant factor VIII (rFVIII) products is the gold-standard treatment for hemophilia A. …”
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Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France by Huamao Mark Lin, Keith L. Davis, James A. Kaye, Katarina Luptakova, Saurabh P. Nagar, Mohamad Mohty

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APPLICATION OF THE INTERNET OF THINGS IN PHARMACEUTICAL INDUSTRY SUPPLY CHAINS by N. Yu. Barkova, D. D. Zherega, E. A. Popova, V. P. Logacheva

“…By adapting the proposed system, the pharmaceutical company can easily monitor and control the quality of the goods during transportation.…”
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Impressive stability-indicating RP-HPLC method for concurrent quantification of salbutamol, guaifenesin, and sodium benzoate in cough syrup: Application of six sigma and green metr... by Alanazi Tahani Y. A., Mahgoub Samar M., Ahmed Hoda A., Almalki Manal A., Alsehli Bandar R., Abdel-Reheim Mustafa Ahmed, Mohammed Osama A., Mohamed Mahmoud A.

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Research on technological innovation decision-making considering government subsidies and corporate reputation. by Yu Kang, Zhe Huang

“…Aiming at the information asymmetry between pharmaceutical enterprises' technological innovation decisions and government subsidy strategy, this paper establishes a differential game model consisting of the government and a single pharmaceutical company, proposes three different government subsidy strategies, and obtains an equilibrium solution with the help of the Hamilton-Jacobi-Bellman equation, taking into consideration of the transmission effect of the enterprise's reputation. …”
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Adopting lean product development in new production system introduction process for sustainable operational performance by Md Hasibul Islam

“…An empirical study was conducted in a multi-national pharmaceutical company, having lean practice for over a decade. …”
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Determination of Trace Amounts of Palladium in Water Samples by Graphite Furnace Atomic Absorption Spectrometry after Dispersive Liquid-Liquid Microextraction by Mohammad Reza Jamali, Yaghoub Assadi, Reyhaneh Rahnama Kozani

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Core-in-cup/liquisol dual tackling effect on azelnidipine buccoadhesive tablet micromeritics, in vitro release, and mucoadhesive strength by Rashad Amira A., El-Helaly Sara Nageeb, Abd El Rehim Randa T., El-Gazayerly Omaima N.

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Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol by Nada Aly H., Zaghloul Abdelazim A., Hedaya Mohsen M., Khattab Ibrahim S.

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A combined multi objective model to supplier evaluation and selection and order allocation using AHP and TOPSIS by Ali Nazeri, Bohlool Ebrahimi, Reza Naderikia

“…Epsilon constraint method is applied to solve the model using a pharmaceutical company data. Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) has carried out to determine the best answer Among Pareto solutions. …”
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Complaints management in the pharmaceutical industry: A Case Study by Marija Stojanovska, Maja Poposka-Stojchevska, Gordana Mitrovska, Stevce Petrovski, Katerina Brezovska

“…To ensure proper complaint management we must understand the importance of providing an effective complaint management system, the regulatory obligations framing it, and the processes of handling complaints, focusing on involving best practices and the potential challenges pharmaceutical companies face. This paper describes the process of handling a complaint that a pharmaceutical company has received from a foreign regulatory agency. …”
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Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review by Lei Lu, Ying Jiang, Ravindran Jaganathan, Yanli Hao

“…Literature search was done on online databases, PubMed, Google Scholar, clinitrials.gov, and browsing through individual ophthalmology journals and leading pharmaceutical company websites.…”
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Under-reported relationship: a comparative study of pharmaceutical industry and patient organisation payment disclosures in the UK (2012–2016) by Piotr Ozieranski, Emily Rickard, Shai Mulinari, Marcell Csanádi

“…Objectives To examine the under-reporting of pharmaceutical company payments to patient organisations by donors and recipients.Design Comparative descriptive analysis of payments disclosed on drug company and charity regulator websites.Setting UK.Participants 87 donors (drug companies) and 425 recipients (patient organisations) reporting payments in 2012–2016.Main outcome measures Number and value of payments reported by donors and recipients; differences in reported payments from/to the same donors and recipients; payments reported in either dataset but not the other one; agreement between donor–recipient ties established by payments; overlap between donor and recipient lists and, respectively, industry and patient organisation data.Results Of 87 donors, 63 (72.4%) reported payments but 84 (96.6%) were mentioned by recipients. …”
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How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis by Quinn Grundy, Fiona Webster, Daniel Z Buchman, Sheryl Spithoff, Ross E G Upshur, Abhimanyu Sud, Matthew Strang

“…Within this context, this study examined how the ‘Suboxone Education Programme’, developed and delivered by a pharmaceutical company as part of a federally regulated risk management program, was presented as a solution to various kinds of risks relating to opioid use in public documents from medical institutions across Canada.Setting These documents were issued during the Canadian opioid crisis, a time when the involvement of industry in health policy was being widely questioned given industry’s role in driving the overprescribing of opioid analgesics and contributing to population-level harms.Design A critical discourse analysis of 69 documents collected between July 2020 and May 2021 referencing the Suboxone Education Program spanning 13 years (2007–2021) from medical, nursing and pharmacy institutions sourced from every Canadian province and territory. …”
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Agro-morphological characterization and assessment of metabolic profiling and anticancer activities in various tribulus (Tribulus terrestris L.) populations by Yasamin Dabaghkar, Ghasem Eghlima, Hossein Behboudi, Mohammadtaghi Ebrahimi, Mansour Ghorbanpour

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Quantitative analysis of quaternary mixtures in topical creams using cutting-edge HPLC technique: environmental impact and sigma methodology by Maha A. Alwaili, Osama A. Mahmoud, Samar M. Mahgoub, Manal A. Almalki, Hassan A. Rudayni, Ahmed A. Allam, Mustafa Ahmed Abdel-Reheim, Osama A. Mohammed, Mahmoud A. Mohamed

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Application of additive manufacturing TaBw01 porous tantalum rod in ARCO stage II osteonecrosis of the femoral head by Jingjie Huang, Yifan Jiang, Yang Peng, Lina Hao, Ran Xiong, Tiao Su, Guangxing Chen

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Optimization and Evaluation of <i>Cannabis</i>-Based Magistral Formulations: A Path to Personalized Therapy by Bożena Grimling, Magdalena Fast, Magdalena Okoniewska, Artur Owczarek, Bożena Karolewicz

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Cleaner Production Quality Regulation Strategy of Pharmaceutical with Collusive Behavior and Patient Feedback by Junmei Rong, Lilong Zhu

“…This paper’s two innovations are as follows: first, it not only considers the collusion between pharmaceutical companies and medical service agencies, but also introduces patient feedback to study drug quality regulation strategies from a microperspective; second, this paper constructs a tripartite evolutionary game model involving cleaner production pharmaceutical companies, medical service agencies, and the governments to analyze the evolutionary stability using the Lyapunov first rule. …”
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The COVID-19 impact: Insights into the pharmaceutical sector through 10-K reports by Shan Wang, Fan Yang, Xinyue Fang, Fang Wang

“…COVID-19 has lasting impacts on pharmaceutical companies, and it is crucial for managers to fully understand and monitor the impact areas to prepare for future organizational resilience building and transformation. …”
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