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    Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of Ange... by Yunyao Jiang, Jingpei Piao, Nan Liu, Jincai Hou, Jianxun Liu, Weicheng Hu

    Published 2020-01-01
    “…The results also suggested that ultrafine powderization and HME may be developed and applied in the pharmaceutical industry.…”
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    Insights into the formulation properties, biocompatibility, and permeability of poorly water-soluble methoxyflavones with PEG400 and propylene glycol by Eze Fredrick Nwude, Jansakul Chaweewan, Srichana Teerapol

    Published 2023-09-01
    “…The TEER values of the Caco-2 cell monolayers indicated that the increased drug transport was partly due to increased tight junction openings, but without compromising the epithelial barrier integrity. The good pharmaceutical and biocompatibility profiles, as well as improved transport of the methoxyflavones in PEG400 and propylene glycol solutions, are suggestive of the worthiness of this approach for further consideration pertaining to the development of these drugs into oral liquid dosage forms.…”
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