Optimization of Protease Activity of Endophytic Bacteria EUA-136 and EUA-139 from Bruguiera gymnorrhiza Using Response Surface Methodology by Anthoni Agustien, Miftahul Zovia, Rima Dwitaviani, Yetti Marlida

“… Protease is a vital enzyme used in industries such as detergents, pharmaceuticals, and animal feed, with a growing demand in the enzyme market. …”
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Selectively expressed RNA molecules as a versatile tool for functionalized cell targeting by Frederik Rastfeld, Marco Hoffmann, Sylvie Krüger, Patrick Bohn, Anne-Sophie Gribling-Burrer, Laura Wagner, Nils Hersch, Carina Stegmayr, Lukas Lövenich, Sven Gerlach, Daniel Köninger, Christina Hoffmann, Helene L. Walter, Dirk Wiedermann, Hajaani Manoharan, Gereon R. Fink, Rudolf Merkel, Heribert Bohlen, Redmond P. Smyth, Maria A. Rueger, Bernd Hoffmann

“…Abstract Targeting of diseased cells is one of the most urgently needed prerequisites for a next generation of potent pharmaceuticals. Different approaches pursued fail mainly due to a lack of specific surface markers. …”
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Impact of cholesterol in encapsulated vitamin E acetate within cocoliposomes by Hudiyanti Dwi, Hidayati Salma Nur, Siahaan Parsaoran, Ngadiwiyana Ngadiwiyana, Nur Abidin, Sari Ratna Indria, Amalia Indrian Rizka, Christa Sherllyn Meida, Patrechia Amanda Chindy, Maharani Adinda Eka

“…Vitamin E acetate (VEA) is commonly used in manufacturing pharmaceuticals, food additives, and animal feeds. However, VEA possesses disadvantages, including low water solubility, low bioavailability, and susceptibility to degradation and oxidation. …”
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INTERNATIONAL ISOTOPES MARKETS by S. Z. Zhiznin, V. M. Timohov

“…Nuclear medicine is developing intensively all over the world thanks to the success in the treatment of various diseases with the help of radioactive pharmaceuticals (radiopharmaceuticals). The article uses empirical data from a forecast study of the global radiopharmaceuticals market made in 2015 by a research company «Markets and Markets» for the European, North American and global markets. …”
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Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits by Qi Yu, Zhengcao Liu, Ahmed Bilal Waqar, Bo Ning, Xianghong Yang, Masashi Shiomi, Mark J. Graham, Rosanne M. Crooke, Enqi Liu, Sijun Dong, Jianglin Fan

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Study protocol for the international Systemic Lupus Erythematosus Prospective Observational Cohort Study (SPOCS): understanding lupus and the role of type I interferon gene signatu... by Raj Tummala, Anna Berglind, Xia Wang, Henk Nab, Barnabas Desta, Edward R Hammond, Farhat Syed

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Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates by Colin W. Howden, Carmelo Scarpignato, Eckhard Leifke, Darcy J. Mulford, Gezim Lahu, Axel Facius, Yuhong Yuan, Richard Hunt

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A comprehensive review on alpha-lipoic acid delivery by nanoparticles by Navid Mosallaei, Amirhossein Malaekeh-Nikouei, Setayesh Sarraf Shirazi, Javad Behmadi, Bizhan Malaekeh-Nikouei

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Convenient estimation of oxytetracycline and polymyxin B by a novel high-performance liquid chromatography method: development and validation by Tanu Chaudhary, Balak Das Kurmi, Dilpreet Singh

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USER ACCEPTANCE OF MOBILE-JKN: INSIGHTS FROM THE TECHNOLOGY ACCEPTANCE MODEL by Ferina Septiani Damanik, Anna Wahyuni Widayanti, Chairun Wiedyaningsih

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NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation by Agata Habas, Srinivasa Reddy Natala, Jon K. Bowden-Verhoek, Emily M. Stocking, Diana L. Price, Wolfgang Wrasidlo, Douglas W. Bonhaus, Martin B. Gill

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Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis by George Joseph, Howard Thom, Jeroen Jansen, Hung-Yuan Cheng, Jason Shafrin, Lauren Zhao, Subhajit Gupta, Nirmish Shah

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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy by Mari Aikio, Hana M. Odeh, Heike J. Wobst, Bo Lim Lee, Úna Chan, Jocelyn C. Mauna, Korrie L. Mack, Bradley Class, Thomas A. Ollerhead, Alice F. Ford, Edward M. Barbieri, Ryan R. Cupo, Lauren E. Drake, Joshua L. Smalley, Yuan-Ta Lin, Stephanie Lam, Reuben Thomas, Nicholas Castello, Ashmita Baral, Jenna N. Beyer, Mohd A. Najar, John Dunlop, Aaron D. Gitler, Ashkan Javaherian, Julia A. Kaye, George M. Burslem, Dean G. Brown, Christopher J. Donnelly, Steven Finkbeiner, Stephen J. Moss, Nicholas J. Brandon, James Shorter

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HEROIC: a 5-year observational cohort study aimed at identifying novel factors that drive diabetic kidney disease: rationale and study protocol by Neil Ashman, Ben Caplin, David Wheeler, Tahseen Ahmad Chowdhury, Kieran Mccafferty, Sinead Knight, Paul Hockings, Stanley L Fan, Johannes Hulthe, Robert Kleta, Vasilios Papastefanou, Hemal Mehta, Alan Salama, Sinela Hadzovic, Lisa Jarl, Robert Unwin, Benjamin Challis, Anna K Sundgren, Muhammad Magdi Yaqoob

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The optimal neoadjuvant treatment strategy for HR+/HER2 + breast cancer: a network meta-analysis by Shiwei Liu, Miao Yu, Exian Mou, Meihua Wang, Shuanghua Liu, Li Xia, Hui Li, Hao Tang, Yajing Feng, Xin Yu, Kun Mi, Hao Wang

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Effects of macitentan and selexipag across prognostic age groups in patients with pulmonary arterial hypertension by Richard Channick, MD, Sarah Medrek, MD, Marion Delcroix, MD, Sean Gaine, MD, Pavel Jansa, MD, PhD, Irene Lang, MD, Vallerie McLaughlin, MD, Sanjay Mehta, MD, Tomas Pulido, MD, Bhagavatula Sastry, MD, Rogerio Souza, MD, PhD, Adam Torbicki, MD, Carol Zhao, MS, Paul Strachan, MD, Peter Agron, PhD, Joseph Yen, PhD, Olivier Sitbon, MD, PhD

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Extraction and Physicochemical Characterization of Mucilage from Opuntia cochenillifera (L.) Miller by Mariel Monrroy, Erick García, Katherine Ríos, José Renán García

“…The prepared mucilage exhibits properties that recommend it as a natural material that can be used as an additive in the chemical, food, pharmaceuticals and cosmetics industries, as well as in decontamination processes.…”
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Cellular MR Imaging by Michel Modo, Mathias Hoehn, Jeff W.M. Bulte

“…Several of these magneto-pharmaceuticals have been FDA-approved or are in late-phase clinical trials. …”
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Advancing Towards a Sustainable Future: A Systematic Review of Sustainable Net Zero Economy Implementation Studies by Vihas Vijay, Sathish A.S.

“…A significant gap is identified in research from developing economies, suggesting an avenue for further exploration, particularly in high-impact industries like pharmaceuticals. The review advocates for global collaboration and interdisciplinary strategies to transition towards sustainable net-zero economies, providing insights for researchers, policymakers, and industry stakeholders. …”
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Antioxidant Activity of Hybrid Sturgeon ( Huso dauricus × Acipenser schrenckii ) Protein Hydrolysate Prepared Using Bromelain, Its Fractions and Purified Peptides by Anwar Noman, Yuxia Wang, Chao Zhang, Sherif Abed

“…The obtained fractions and peptides with antioxidant activity could be used as natural substitutes for synthetic antioxidants, especially in food and pharmaceuticals.…”
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