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5101
Performance features of virus removal filters with novel regenerated cellulose hollow fiber membranes
Published 2025-02-01“…Following the revision of International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) Q5A, the guidelines for the virus safety of biopharmaceuticals now state that an effective viral clearance process should achieve a viral reduction of 4 log10 or greater. …”
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5102
Safety of proton pump inhibitors
Published 2016-08-01“…Proton pump inhibitors is the class of pharmaceuticals that block N+/K+-ATPase of gastric parietal cells. …”
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5103
Allylic C–H oxygenation of unactivated internal olefins by the Cu/azodiformate catalyst system
Published 2025-01-01“…Abstract Allylic ethers and alcohols are essential structural motifs commonly present in natural products and pharmaceuticals. Direct allylic C–H oxygenation of internal alkenes is one of the most direct methods, bypassing the necessity for an allylic leaving group that is needed in the traditional Tsuji–Trost reaction. …”
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5104
Optimising plant form and function for controlled environment agriculture in space and on earth
Published 2023-09-01“…Plants can serve multiple roles, from providing nutritious foods and wellbeing to acting as biofactories for essential pharmaceuticals. The need for robust and efficient controlled environment agriculture (CEA) systems that are integral to life support is explored. …”
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5105
Impact of Urban Xenobiotics on Mycorrhizal Associations in Urban Plants
Published 2024-12-01“…Currently, the demand for pharmaceuticals, compared to the growing population, has placed a risk on the urban plant. …”
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5106
Comparative of relation of American, German, French and Russian guidelines on irritable bowel syndrome management
Published 2016-08-01“…On the contrary, the German, French and Russian guidelines pay special attention to general recommendations and dietary modification and consider above-mentioned pharmaceuticals as quite effective. Conclusion. Presented guidelines are similar to each other in respect of their plot; however significantly differ in diagnostic approach to IBS and assessment of efficacy of series of drugs. …”
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5107
An Emerging Multi-mechanism and Multi-modal Approach in Interventional Glaucoma Therapy
Published 2024-11-01“…The era of interventional glaucoma has seen the development of selective laser trabeculoplasty (SLT), procedural pharmaceuticals, and minimally invasive glaucoma surgeries (MIGS). …”
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5108
Engineered Magnetic Carbon-Based Adsorbents for the Removal of Water Priority Pollutants: An Overview
Published 2021-01-01“…The performance of these adsorbents is analyzed for the removal of fluoride, arsenic, heavy metals, dyes, pesticides, pharmaceuticals, and other emerging and relevant water pollutants. …”
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5109
Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties
Published 2022-01-01“…The carboxylic acid moiety is known to be a crucial functionality in many pharmaceutically active compounds. Despite its common use as a key functionality in drugs, its presence in a lead molecule is often associated with poor pharmacokinetic properties and toxicity. …”
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5110
Iron-Catalyzed Cross-Dehydrogenative Coupling
Published 2025-01-01“…These methods have been successfully applied in synthesizing complex molecules and pharmaceuticals, highlighting the versatility and efficiency of iron catalysis.…”
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5111
Catalytic transformation of carbon dioxide into seven-membered heterocycles and their domino transformation into bicyclic oxazolidinones
Published 2025-02-01“…The results described herein significantly expand on the use of CO2 as a cheap and versatile carbon feedstock generating elusive heterocycles and pharmaceutically relevant compounds.…”
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5112
Optimisation and In Vivo Evaluation of Pectin Based Drug Delivery System Containing Curcumin for Colon
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5113
Identification of Antiapoptotic Protein Kinases and Phosphatases by a Functional Genomics Approach
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5114
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5117
Biomimetic Dehydrogenative Intermolecular Formal Allylic Amidation of Branched α‐Olefins
Published 2025-01-01“…Abstract Allylic amide moieties are commonly encountered in natural products and are privileged structures in pharmaceuticals and agrochemicals. Moreover, because allylic amide can be to converted into an array of high‐value motifs, they have been widely employed in organic synthesis. …”
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5118
Accelerated enzyme engineering by machine-learning guided cell-free expression
Published 2025-01-01“…We use these data to build augmented ridge regression ML models for predicting amide synthetase variants capable of making 9 small molecule pharmaceuticals. Over these nine compounds, ML-predicted enzyme variants demonstrate 1.6- to 42-fold improved activity relative to the parent. …”
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5119
Genome sequence of Streptomyces antioxidans MUSC 164T isolated from mangrove forest
Published 2018-04-01“…Here we report the high quality genome sequence of MUSC 164T, while 34 discussing its genome potential to produce pharmaceutically important compounds.…”
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5120
Phytochemical profile, therapeutic potentials, nutritional composition, and food applications of ginger: a comprehensive review
Published 2025-02-01“…This article also explores the applications of ginger in pharmaceuticals, nutraceuticals, and functional foods, highlighting its value in various industries. …”
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