Deoxygenative photochemical alkylation of secondary amides enables a streamlined synthesis of substituted amines by Antonio Pulcinella, Stefano Bonciolini, Robin Stuhr, Damiano Diprima, Minh Thao Tran, Magnus Johansson, Axel Jacobi von Wangelin, Timothy Noël

“…Abstract Secondary amines are vital functional groups in pharmaceuticals, agrochemicals, and natural products, necessitating efficient synthetic methods. …”
Get full text

Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179 by Yuchen Li, Chaemin Lim, Taylor Dismuke, Daniel S. Malawsky, Sho Oasa, Zara C. Bruce, Carolin Offenhäuser, Ulrich Baumgartner, Rochelle C. J. D’Souza, Stacey L. Edwards, Juliet D. French, Lucy S. H. Ock, Sneha Nair, Haran Sivakumaran, Lachlan Harris, Andrey P. Tikunov, Duhyeong Hwang, Coral Del Mar Alicea Pauneto, Mellissa Maybury, Timothy Hassall, Brandon Wainwright, Santosh Kesari, Gregory Stein, Michael Piper, Terrance G. Johns, Marina Sokolsky-Papkov, Lars Terenius, Vladana Vukojević, Leon F. McSwain, Timothy R. Gershon, Bryan W. Day

Get full text

Clozapine-carboxylic acid plasticized co-amorphous dispersions: Preparation, characterization and solution stability evaluation by Ali Ahmed Mahmoud Abdelhaleem, Ali Adel Ahmed, Maghrabi Ibrahim Abdullah

Get full text

Anti-HSV-1 agents: an update by Wenwen Lv, Lei Zhou, Jia Wu, Jishuai Cheng, Yongzhong Duan, Wen Qian

Get full text

Emerging Technologies and Generic Assays for the Detection of Anti-Drug Antibodies by Michael A. Partridge, Shobha Purushothama, Chinnasamy Elango, Yanmei Lu

Get full text

HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding by Rui Zhu, Rui Zhu, Rui Zhu, Jie Wu, Ruiying Chen, Mo Zhou, Mo Zhou, Mo Zhou, Shinuo Cao, Shinuo Cao, Shinuo Cao, Zhi Wu, Zhi Wu, Zhi Wu, Ligang Wang, Lei Zhang, Shanyuan Zhu, Shanyuan Zhu, Shanyuan Zhu

Get full text

Amylin as a Neuroendocrine Hormone by Andrew A. Young

Get full text

Amoxicillin/Clavulanic Acid for the Treatment of Odontogenic Infections: A Randomised Study Comparing Efficacy and Tolerability versus Clindamycin by Archiel Launch Tancawan, Maria Noemi Pato, Khamiza Zainol Abidin, A. S. Mohd Asari, Tran Xuan Thong, Puja Kochhar, Chandra Muganurmath, Monique Twynholm, Keith Barker

Get full text

Analytical Method Development and Validation for the Quantification of Acetone and Isopropyl Alcohol in the Tartaric Acid Base Pellets of Dipyridamole Modified Release Capsules by... by Sriram Valavala, Nareshvarma Seelam, Subbaiah Tondepu, V. Shanmukha Kumar Jagarlapudi, Vivekanandan Sundarmurthy

“…The method validation was carried out with regard to the guidelines for validation of analytical procedures Q2 demanded by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). All the validation characteristics were meeting the acceptance criteria. …”
Get full text

Advances in oral dissolving film research in the food field by Yue Li, Min Zhao, Ming-Yue Zhao, Bin Li, Jin-Long Tian

“…With promising applications in pharmaceuticals and especially food industry, ODFs offer a highly absorbable method for delivering nutritious and healthy foods. …”
Get full text

Preparation methods, biological activities, and potential applications of marine algae oligosaccharides: a review by Li-Xin Zheng, Yang Liu, Shijie Tang, Wancong Zhang, Kit-Leong Cheong

“…Highlights of the biological activities of MAO and their potential applications in food, nutraceutical, and pharmaceuticals would also be discussed and summarized.…”
Get full text

Effects of Pervari Honey from Türkiye on Proliferation, Oxidative Stress, and Apoptosis of Human Breast Cancer Cells by Ramazan Üzen, Hamiyet Altuntaş, Mustafa Çakır, Pınar Altın Çelik, Muazzez Derya Andeden

“…The present study suggests that honey is a promising source to produce pharmaceuticals and nutraceuticals for breast cancer therapy.…”
Get full text

Effectiveness of heat source/sink and Lorentz force constraints in a non-Newtonian peristaltic arterial blood hybrid nanofluid past an overlapping stenotic artery by Vedhesh Dhinakaran, Keerthi Devarajan Anuradha, J.U. Viharika, Umair Khan, Nermeen Abdullah, Samia Elattar

“…The findings of this investigation may have benefits in various academic fields, including pharmaceuticals and other industries. In addition, they are remarkably beneficial in the treatment of numerous cardiovascular diseases.…”
Get full text

WASTEWATER TREATMENT OF PIGMENT PRODUCTION PLANTS IN TWO STAGES: PREPARED ACTIVATED CARBON AND ELECTRODIALYSIS PROCESS by Mohammed Q. Gubari, Bilal S. Taha

“…They are widely used in dyestuff, cosmetics, food products, pharmaceuticals, manufacturing processes, etc. This study focuses on the removal of pigments and other components from wastewater discharged from pigment plants. …”
Get full text

Eosinophil is a predictor of severe immune-related adverse events induced by ipilimumab plus nivolumab therapy in patients with renal cell carcinoma: a retrospective multicenter co... by Yoshihiko Tasaki, Shuzo Hamamoto, Shimpei Yamashita, Junya Furukawa, Kazutoshi Fujita, Ryotaro Tomida, Makito Miyake, Noriyuki Ito, Hideto Iwamoto, Yoshihisa Mimura, Yosuke Sugiyama, Rei Unno, Atsushi Okada, Takahiro Yasui, Yoko Furukawa-Hibi

Get full text

Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

Get full text

Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models by Andrea Mancini, Alessandro Colapietro, Loredana Cristiano, Alessandra Rossetti, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Héctor Perez-Montoyo, Marc Yeste-Velasco, Jose Alfon, Carles Domenech, Claudio Festuccia

Get full text

Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review by Manjusha Bhange, Darshan Telange

Get full text

Comment on “The Effect of Chromium Picolinate Supplementation on the Pancreas and Macroangiopathy in Type II Diabetes Mellitus Rats” by Hitesh Verma, Rajeev Garg

Get full text

Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk by Fahad M. Aldakheel, Hadeel Alnajran, Shatha A. Alduraywish, Ayesha Mateen, Mohammed S. Alqahtani, Rabbani Syed

Get full text