Safety and efficacy of switching from adalimumab to sarilumab in patients with rheumatoid arthritis in the ongoing MONARCH open-label extension by Gerd R Burmester, Mark C Genovese, Vibeke Strand, Gregory St John, Andrea Rubbert-Roth, Howard Amital, Tatiana Raskina, Antonio Gómez-Centeno, Claudia Pena-Rossi, Leon Gervitz, Karthinathan Thangavelu, Susan Boklage

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Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats by Muhammad Aslam, Ali Akbar Sial

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OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma by Kinjal Desai, Siyi Wanggou, Erika Luis, Heather Whetstone, Chunying Yu, Robert J. Vanner, Hayden J. Selvadurai, Lilian Lee, Jinchu Vijay, Julia E. Jaramillo, Jerry Fan, Paul Guilhamon, Michelle Kushida, Xuejun Li, Gregory Stein, Santosh Kesari, Benjamin D. Simons, Xi Huang, Peter B. Dirks

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Antimicrobial Usage in Smallholder Poultry Production in Nigeria by Oladeji Bamidele, Tunde A. Amole, Oluwafikayo A. Oyewale, Olayinka O. Bamidele, Abdulmojeed Yakubu, Uduak E. Ogundu, Folasade O. Ajayi, Waheed A. Hassan

“…The western method (pharmaceuticals) was practiced by a large proportion of farmers (60%), either solely (25%) or in combination with EVM (35%). …”
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A Review of Current Issues Underlying Colon Cleansing before Colonoscopy by Lawrence C Hookey, Stephen Vanner

“…The present review examines four current issues related to the efficacy, patient tolerance and safety of the following bowel cleansing agents: oral sodium phosphate (NaP), polyethylene glycol (PEG) and magnesium citrate (Pico-Salax, Ferring Pharmaceuticals Inc, Canada), an agent recently made available in Canada. …”
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Comparison of the Efficiency of Ultraviolet/Zinc Oxide (UV/ZnO) and Ozone/Zinc Oxide (O3/ZnO) Techniques as Advanced Oxidation Processes in the Removal of Trimethoprim from Aqueous... by Moayede Taie, Abdolmajid Fadaei, Mehraban Sadeghi, Sara Hemati, Gashtasb Mardani

“…Nowadays, advanced oxidation processes, particularly photocatalyst process and catalytic ozonation by ZnO nanoparticles, are the most efficient method of eliminating pharmaceuticals. The purpose of this study was to compare the efficiency of ultraviolet/zinc oxide (UV/ZnO) and ozone/zinc oxide (O3/ZnO) techniques as advanced oxidation processes in the removal of trimethoprim (TMP) from aqueous solutions. …”
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Risk characterisation of chemicals of emerging concern in real-life water reuse applications by Jan C. Specker, Antonia Praetorius, Milo L. de Baat, Nora B. Sutton, Annemarie P. van Wezel

“…However, a thorough risk assessment of CECs during water reuse is currently limited due to a focus on a defined class of contaminants in the literature, i.e., pharmaceuticals, and falls short of per- and polyfluoroalkyl substances. …”
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Occurrence of Acetaminophen, Amoxicillin, Diclofenac and Methylparaben in Lagos and Ologe Lagoons, Lagos, Nigeria by O.S. Folarin, A.A. Otitoloju, N.H. Amaeze, J.K. Saliu

“…The study established that there are active pharmaceuticals compounds and excipients present in the Nigerian aquatic environment which are  micropollutants of emerging environmental concerns and of significant ecological risk. …”
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Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment by Diana Ilyaskina, Yumi Nakadera, Yumi Nakadera, Marja H. Lamoree, Joris M. Koene, Pim E. G. Leonards

“…Pharmaceuticals such as selective serotonin reuptake inhibitors (SSRIs), are increasingly detected in aquatic environments, posing potential risks to non-target organisms, because many of those substances are widely shared neuromodulator. …”
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Occurrence of Acetaminophen, Amoxicillin, Diclofenac and Methylparaben in Lagos and Ologe Lagoons, Lagos, Nigeria by O.S. Folarin, A.A. Otitoloju, N.H. Amaeze, J.K. Saliu

“…The study established that there are active pharmaceuticals compounds and excipients present in the Nigerian aquatic environment which are  micropollutants of emerging environmental concerns and of significant ecological risk. …”
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Telaprevir in treatment of chronic hepatitis C: safety issues by T. M. Ignatova

“…Special attention is given to prophylaxis of interactions with other pharmaceuticals, as telaprevir is P450 (СYP) 3A4 substrate and inhibitor and P-glycoprotein transporter.Conclusion. …”
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High Stability Single-Port Dual Band Microwave Sensor Based on Interdigital Capacitor Structure With Asymmetry Branch Feedline by Syah Alam, Indra Surjati, Lydia Sari, Raden Deiny Mardian, Teguh Firmansyah, Muhammad Iqbal, Slamet Widodo, Mudrik Alaydrus, Zahriladha Zakaria

“…Therefore, this sensor can be recommended for several applications such as biomedical industry, pharmaceuticals and material quality control especially for outdoor measurements that are potentially affected by electromagnetic interference and disturbance.…”
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Microalgae-based bioremediation of refractory pollutants: an approach towards environmental sustainability by Mostafa M. El-Sheekh, Hala Y. El-Kassas, Sameh S. Ali

“…Therefore, this review discusses the mechanism and the ability of different microalgal species to mitigate persistent refractory pollutants, such as industrial effluents, dyes, pesticides, and pharmaceuticals. Also, this review paper provided insight into the production of nanomaterials, nanoparticles, and nanoparticle-based biosensors from microalgae and the immobilization of microalgae on nanomaterials to enhance bioremediation process efficiency. …”
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Bridging Molecular Docking to Molecular Dynamics to Enlighten Recognition Processes of Tailored D-A/D-A-D Types' AIEgens with HSA/BSA by Harun Nalçakan, Gülbin Kurtay

“…In this scope, we performed a detailed molecular dock-ing study of Donor (D)-Acceptor (A) or D-A-D type luminogens with two blood proteins; namely bovine serum albumin (BSA) and human serum albumin (HSA), which appeared as robust carriers of several pharmaceuticals against preliminary cancer diseases. Our results revealed that the binding scores of the Dn-An or Dn-An-Dn:BSA complexes ranged from -8.5 to -11.7 kcal/mol while Dn-An or Dn-An-Dn:HSA complexes showed scores varying from -8.4 to -10.5 kcal/mol. …”
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The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade by Christopher A. Jones, David G. Chapman, Peter Weimersheimer, Luca Fernandez, Oscar Alejandro Mesa, Christian Peters, Bart M. Vanaudenaerde, Mitchell C. Norotsky, Robin Vos

“…., hospitalizations, pharmaceuticals, devices), and non-medical direct costs such as monitoring and professional caregiving. …”
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Green approach for the synthesis of zinc oxide nanoparticles from methanolic stem extract of Andrographis paniculata and evaluation of antidiabetic activity: In silico GSK-3β analy... by Kumar Gopal Nithesh, Ali Mohammad, Raghunathanaidu Bharathi Doddla, Ahmed Syed Sagheer, Komalkumar Chandan, Ananth Gowda KM Doddi Hanumaiah, Prajwal Chamanahalli Balaraju, Shakeel Faiyaz

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Effect of Volume and Renewal of the Storage Media on the Release of Monomer from Dental Composites by Sima Shahabi, Maryam Sayyari, Sima Sadrai, Sara Valizadeh, Hamidreza Hajizamani, Alireza Sadr

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Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry by Frederick L Locke, Grant Schofield, Marcelo Pasquini, Matthew J Frigault, Cameron J Turtle, Stephen Lim, Brian Hill, Samantha Jaglowski, Caron A Jacobson, Gunjan Shah, Daniel J Landsburg, Michael Heim, Stephen Ronan Foley, Ron Ram, Peter A Riedell, Leslie L Popplewell, Ranjan Tiwari, Marta Majdan, Aisha Masood

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The Effects of TLR Activation on T-Cell Development and Differentiation by Bo Jin, Tao Sun, Xiao-Hong Yu, Ying-Xiang Yang, Anthony E. T. Yeo

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Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Mohammed M. Safhi, Mohammad Firoz Alam, Sivagurunathan Moni Sivakumar, Tarique Anwer

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