Theoretical Investigation of the Structural, Spectroscopic, Electronic, and Pharmacological Properties of 4-Nerolidylcathecol, an Important Bioactive Molecule by Renyer A. Costa, Earle Silva A. Junior, Jaqueline de A. Bezerra, Josiana Moreira Mar, Emerson S. Lima, Maria Lucia B. Pinheiro, Diego V. C. Mendonça, Guilherme Braule P. Lopes, Adjane Dalvana S. Branches, Kelson M. T. Oliveira

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Experiences of and response to the COVID-19 pandemic at private retail pharmacies in Kenya: a mixed-methods study by Edwine Barasa, Sassy Molyneux, Jacinta Nzinga, Audrey Mumbi, Peter Mwangi Mugo, Daniella Munene, Collins Jaguga, Davy Odhiambo, Elizabeth Ominde-Ogaja, Mercy Maina, Michael Mungoma, Nadia Butt, Sultani Matendechero, Titus Kahiga, Eric Sedah, Sylvia Opanga

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Enhancing immunotherapy efficacy with synergistic low-dose radiation in metastatic melanoma: current insights and prospects by Zahid Rafiq, Mingyo Kang, Hampartsoum B. Barsoumian, Gohar S. Manzar, Yun Hu, Carola Leuschner, Ailing Huang, Fatemeh Masrorpour, Weiqin Lu, Nahum Puebla-Osorio, James W. Welsh

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ISCOM-type matrix from beta-escin and glycyrrhizin saponins by V. Petkov, S. Tsibranska, I. Manoylov, L. Kechidzhieva, K. Ilieva, S. Bradyanova, N. Ralchev, N. Mihaylova, N. Denkov, A. Tchorbanov, S. Tcholakova

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Synthesis of Surfactants Derived from 2-Mercaptobenzimidazole and Study of Their Acute Toxicity and Analgesic and Psychotropic Activities by Terence Nguema Ongone, Latyfa El Ouasif, Mostafa El Ghoul, Redouane Achour, Hind Chakchak, Meryem El Jemli, Yahia Cherrah, Katim Alaoui, Amina Zellou

“…These results argue in favor of a possible integration of the most active salts tested in the pharmaceutical industry owing to their analgesic and sedative effects.…”
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Evaluation of Yield and Physicochemical Quality of Pentadesma butyracea Butter Obtained by Different Traditional Extraction Methods in Ghana by Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Jacob K. Agbenorhevi, Nana Baah Pepra-Ameyaw

“…The butter has potential use in the food, pharmaceutical, and cosmetic industries. The study investigated traditional PBSB processing methods in Ghana and evaluated their effects on yield, physicochemical parameters, and fatty acid composition. …”
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Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing by Julia Baumeister, Maximilian Meudt, Sybille Ebert, Frank Rosenau, Boris Mizaikoff, Michaela Blech, Kristina M. J. Aertker, Fabian Higel

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Economic impact of medication non-adherence by disease groups: a systematic review by Victoria Garcia-Cardenas, Rachelle Louise Cutler, Fernando Fernandez-Llimos, Michael Frommer, Charlie Benrimoj

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Unmasking MRSA antibiotic resistance: the impact of environment, pollution, and healthcare quality—a nationwide exploration in China: a comprehensive analysis spanning 2014 to 2021... by Yi-Chang Zhao, Ming-Xuan Xiao, Zhi-Hua Sun, Jia-Kai Li, Huai-yuan Liu, Bi-Kui Zhang, Hua-Lin Cai, Wei Cao, Feng Yu, Miao Yan

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RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis by Qin Y, Liao S, Sun J, Ye H, Li J, Pan J, He J, Xia Z, Shao Y

“…Yuting Qin,1,* Shuanglin Liao,1,* Jianbo Sun,2 Huiyun Ye,1 Jiafu Li,1 Jiahui Pan,1 Junbing He,3 Zhengyuan Xia,4,5 Yiming Shao1,6 1Dongguan Key Laboratory of Sepsis Translational Medicine, The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 2Dongguan Key Laboratory of Chronic Inflammatory Diseases, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 3The Key Laboratory of Organ Dysfunction and Protection Translational Medicine, Jieyang Medical Research Center, Jieyang People’s Hospital, Jieyang, Guangdong, People’s Republic of China; 4Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China; 5State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 6The Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yiming Shao, Dongguan Key Laboratory of Sepsis Translational Medicine, the Intensive Care Unit,The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road 42, Tangxia Town, Dongguan, Guangdong Province, 523710, People’s Republic of China, Tel +86 18826690188, Email sym@gdmu.edu.cn Zhengyuan Xia, Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China, Tel +852-68798794, Email zyxia@hku.hkAbstract: Reversion inducing cysteine rich protein with kazal motifs (RECK), a Kazal motif-containing protein, regulates pro-inflammatory cytokines production, migration of inflammatory cells, vascular endothelial growth factor (VEGF) and Wnt pathways and plays critical roles in septic inflammatory storms and vascular endothelial dysfunction. …”
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Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4 by Ming Zhang, Chun-Mei Wang, Jing Li, Zhao-Jie Meng, Sheng-Nan Wei, Ji Li, Richard Bucala, Yu-Lin Li, Li Chen

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Substituting Fish Meal with Tubiechong (Eupolyphaga sinensis) By-Product in the Diets of Largemouth Bass (Micropterus salmoides): Effects on Growth, Meat Quality, and Liver Health by Yuhua Yue, Binbin Tong, Mingshi Chen, Xiaoxue Bao, Yanming Qiu, Ying Yang, Hui Yu, Yingying Yu

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Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice by Chengfen Wang, Yujing Xia, Yuanyuan Zheng, Weiqi Dai, Fan Wang, Kan Chen, Jingjing Li, Sainan Li, Rong Zhu, Jing Yang, Qin Yin, Huawei Zhang, Junshan Wang, Jie Lu, Yingqun Zhou, Chuanyong Guo

“…Our results described a new pharmaceutical to provide more effective therapies for immune hepatitis.…”
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Phenotypic plasticity vs. local genetic adaptation: essential oil diversity of natural immortelle (Helichrysum italicum (Roth.) G.Don) populations along eastern Adriatic coast by Tonka Ninčević Runjić, Dejan Pljevljakušić, Marko Runjić, Martina Grdiša, Martina Grdiša, Zlatko Šatović, Zlatko Šatović

“…The essential oil of Helichrysum italicum (Roth) G.Don, commonly known as immortelle, is produced in Mediterranean countries to meet the increasing demand of the cosmetic and pharmaceutical industries. This study focused on the analysis of secondary metabolites, specifically essential oils, extracted from plants grown from the seeds of natural immortelle populations collected along the eastern Adriatic coast and cultivated ex situ under uniform conditions. …”
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Enhancing the quality indicators and shelf-life of cantonese mooncakes by employing different flour complex ratios formulating crusts to minimize oil penetration by Li-Ya Tseng, Ping-Hsiu Huang, Jhih-Ying Ciou, Yu-Wei Chen, Yeu-Ching Shi, Chia-Lung Wang, Chih-Yao Hou, Ming-Kuei Shih

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Fatty Acid Profile and Chemical Composition of Three Populations of Southern Cattail (Typha domingensis) from South of Iran by Mona Shojaee Barjouee, Massoumeh Farasat, Mehrnoosh Tadayoni

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The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review by Olivier Uwishema, Ece Karabulut, Dalal Sheikhah, Burhan Kantawala, Misgana Gallo, Fatima Soufan, Magda Wojtara

“…All trials have noted the supremacy of CRT compared to pharmaceutical treatment or other therapeutic methods. …”
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Carcinogenic and non-carcinogenic risk estimation of indoor TVOCs, RSPM, FPM and SFPM on young women dwellers: a case study from the capital city of Uttar Pradesh, India by Farheen Zehra, Samridhi Dwivedi, Mohd Akbar Ali, P. S. Rajinikanth, Alfred Lawrence

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Diagnostics and treatment of chronic constipation in adults: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, A. S. Trukhmanov, Ye. A. Poluektova, Ye. K. Baranskaya, O. S. Shifrin, T. L. Lapina, M. F. Osipenko, V. I. Simanenkov, I. B. Khlynov

“…Successful treatment of constipation requires correct detection of its cause, following essential dietary recommendations and stepwise application of pharmaceutical agents.…”
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Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors by Alessandro Papale, Ilaria Maria Morella, Marzia Tina Indrigo, Rick Eugene Bernardi, Livia Marrone, Francesca Marchisella, Andrea Brancale, Rainer Spanagel, Riccardo Brambilla, Stefania Fasano

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