Mutational Analysis of a Familial Adenomatous Polyposis Pedigree with Bile Duct Polyp Phenotype by Li-jun Xie, Dan-dan Ruan, Jian-hui Zhang, Yi Li, Li Chen, Mao-lin Yan, Ming-dian Yu, Jie-wei Luo, Hui-zhen Zhang

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Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy by Baoyi Feng, Chenxi Jin, Zhenzhe Cheng, Xingle Zhao, Zhuoer Sun, Xiaofei Zheng, Xiang Li, Tingting Dong, Yong Tao, Hao Wu

“…In this review, we summarized mitochondrial biological functions related to SGNs and discussed interaction between mitochondrial dysfunction and AN, as well as existing mitochondrion treatment for SNHL. Pharmaceutical exploration to protect mitochondrion dysfunction is a feasible and effective therapeutics for AN.…”
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The Effect of Eighteen-Month Metformin Treatment in Obese Adolescents: Comparison of Results Obtained in Daily Practice with Results from a Clinical Trial by Marloes P. van der Aa, Vera Hoving, Ewoudt M. W. van de Garde, Antonius de Boer, Catherijne A. J. Knibbe, Marja M. J. van der Vorst

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Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies by Yuze Yuan, Nan Ran, Lingxin Xiong, Guoqiang Wang, Xuewa Guan, Ziyan Wang, Yingqiao Guo, Zhiqiang Pang, Keyong Fang, Junying Lu, Chao Zhang, Ruipeng Zheng, Jingtong Zheng, Jie Ma, Fang Wang

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Clinical Holistic Medicine: Treatment of Physical Health Problems Without a Known Cause, Exemplified by Hypertension and Tinnitus by Søren Ventegodt, Mohammed Morad, Isack Kandel, Joav Merrick

“…Biomedicine is often unable to find a cure in these situations, leaving the problem unsolved or leaving the patient on a palliative pharmaceutical cure, which is often for a lifetime. In this case, consciousness-based, holistic medicine could be an alternative. …”
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Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine by Kerry Rennie, Andrée Gruslin, Markus Hengstschläger, Duanqing Pei, Jinglei Cai, Toshio Nikaido, Mahmud Bani-Yaghoub

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An assessment of South African policy and strategic framework for the development of a sufficient, equitably distributed and well-performing health workforce for the implementation... by S V Mokoena, P Naidoo

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Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population by Ming-Kai Tsai, Hui-Min David Wang, Jeng-Chuan Shiang, I-Hung Chen, Chih-Chiang Wang, Ya-Fen Shiao, Wen-Sheng Liu, Tai-Jung Lin, Tsung-Ming Chen, Ya-Huey Chen

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Phenols from Vaccinium dunalianum Wight: Secondary Mass Spectrometry Fragmentation and Neuroprotective Effect by ZHOU Tang, WANG Ji, QIAO Wenhao, LIN Zhiqi, ZHU Hongbo, CHANG Yue, HU Weiyan, ZHANG Rongping, CHEN Xinglong

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Towards quantifying exfiltration from in situ sanitary sewer pipes by John F. Griffith, Joshua A. Steele, Adriana Gonzalez-Fernández, Kenneth C. Schiff

“…Most previous measurements of sanitary sewer exfiltration have been done in the laboratory, in the field using natural, chemical or pharmaceutical tracers or modeled. Relatively few studies have employed physical measurements of volume loss in field settings. …”
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Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society by V. T. Ivashkin, M. V. Mayevskaya, Ch. S. Pavlov, Yu. P. Sivolap, V. D. Lunkov, M. S. Zharkova, R. V. Maslennikov

“…Short therapeutic interventions practice helps to cope with alcoholic issue at any stage, gives the chance to motivate the patient, including the treatment of addiction to alcohol, intake of drugs. Specific pharmaceutical therapy is carried out at alcoholic hepatitis in relation to severity and alcoholic liver cirrhosis. …”
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Comparison between the HLA-B∗58 : 01 Allele and Single-Nucleotide Polymorphisms in Chromosome 6 for Prediction of Allopurinol-Induced Severe Cutaneous Adverse Reactions by Niwat Saksit, Nontaya Nakkam, Parinya Konyoung, Usanee Khunarkornsiri, Wongwiwat Tassaneeyakul, Pansu Chumworathayi, Sirimas Kanjanawart, Chonlaphat Sukasem, Alisara Sangviroon, Oranuch Pattanacheewapull, Wichittra Tassaneeyakul

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From guideline to practice: three years of ICH S11 insights and recommendations by Diana Tavares, Hsiao-Tzu Chien, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter Theunissen, Peter van Meer, Peter van Meer, Peter van Meer, Karen Van Malderen

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Antimicrobial activity of indigenous Oscillatoria spp. against prevalent bacterial diseases in fish and shellfish by Jannatul Nayeem, Sumit Kanti Dey, Proma Dey, Mohammed Abdullah Ayoun, Dipa Debi, Mohammed Nurul Absar Khan, Helena Khatoon

“…Thus, Oscillatoria spp. contain potential antibacterial substances that facilitate detailed analysis of Oscillatoria spp. bioactive compounds for creating novel antibiotics and benefitting both aquaculture and pharmaceutical industries.…”
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Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives by Virendra Kumar Yadav, Seshathiri Dhanasekaran, Nisha Choudhary, Deepak Nathiya, Vishal Thakur, Rachna Gupta, Sheersha Pramanik, Pankaj Kumar, Nishant Gupta, Ashish Patel

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The Influence of Alcohol Consumption in Conjunction with Sex Hormone Deficiency on Ca/P Ratio in Rats by Karina Bortolin Lodi, Adriana Mathias Pereira da Silva Marchini, Ana Maria do Espírito Santo, Sigmar de Mello Rode, Leonardo Marchini, Rosilene Fernandes da Rocha

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Comparison of the effectiveness of temporomandibular joint osteoarthritis treatment with corticosteroids, hyaluronic acid, and platelet-rich plasma mono-therapy by I. A. Shynchukovskyi, O. H. Tereshchuk

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The Dynamics of Type 2 Diabetes Mellitus Prevalence and Management Rates among Rural Population in Henan Province, China by Xiaotian Liu, Ling Wang, Panpan Wang, Ruihua Liu, Kaili Yang, Xinling Qian, Jingjing Fan, Songcheng Yu, Yuqian Li, Chongjian Wang

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The development and validation of an UV-Vis spectrophotometric method for the determination of ciprofloxacin in raw material and dosage forms by Timothé Mavanga Mabaya, Jocelyn Mankulu Kakumba, Mannix Mayangi Makola, Adelard Mbenza Puati, Didi Mana Kialengila, Jean Mavar Tayey Mbay, Jeremie Mbinze

“…Conclusion The validated method is suitable for routine quantification of ciprofloxacin HCl as raw API or in tablet forms, with revalidation needed for other pharmaceutical forms. …”
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Diabetic Macular Edema Treatment with Bevacizumab Does Not Depend on the Retinal Nonperfusion Presence by Bogumiła Sędziak-Marcinek, Sławomir Teper, Elżbieta Chełmecka, Adam Wylęgała, Mateusz Marcinek, Mateusz Bas, Edward Wylęgała

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