Qualitative Phytochemical Profiling and In Vitro Antioxidant Potential Evaluation of South African Momordica Balsamina Linn Fruit Pulp by Buang Matseke, Sipho Mapfumari, Mmamosheledi Mothibe

Get full text

Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD by Zayed Aref, Babaresh Wahby M., Darweesh Ruba S., El-Elimat Tamam

Get full text

Specific detection of tartaric acid chiral isomers based on centrosymmetric terahertz metamaterial sensors by Xujun Xu, Zhen Sun, Guocui Liu, Jianjun Liu, Yong Du

“…L-, D-, DL-tartaric acids have different uses in food additives and pharmaceutical fields. Traditional detection methods, such as fluorescence detection, have problems such as destructive and non-specific characters. …”
Get full text

Efficacy and Safety of Ropivacaine Addition to Intrathecal Morphine for Pain Management in Intractable Cancer by Ying Huang, Xihan Li, Tong Zhu, Jian Lin, Gaojian Tao

Get full text

Morpho-phylogenetic evidence reveals novel hyphomycetous fungi on medicinal plants in Southwestern China by Hong-Zhi Du, Ning-Guo Liu, Na Wu, Ratchadawan Cheewangkoon, Jian-Kui Liu

Get full text

Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting by Martina A. McAteer, Daniel R. McGowan, Gary J. R. Cook, Hing Y. Leung, Tony Ng, James P. B. O’Connor, Luigi Aloj, Anna Barnes, Phil J. Blower, Kevin M. Brindle, John Braun, Craig Buckley, Daniel Darian, Paul Evans, Vicky Goh, David Grainger, Carol Green, Matt G. Hall, Thomas A. Harding, Catherine D. G. Hines, Simon J. Hollingsworth, Penny L. Hubbard Cristinacce, Rowland O. Illing, Martin Lee, Baptiste Leurent, Sue Mallett, Radhouene Neji, Natalia Norori, Nora Pashayan, Neel Patel, Kieran Prior, Thomas Reiner, Adam Retter, Alasdair Taylor, Jasper van der Aart, Joseph Woollcott, Wai-Lup Wong, Jan van der Meulen, Shonit Punwani, Geoff S. Higgins

Get full text

Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis by Chuanxin Liu, Xiaobin Huang, Jiao Kong, Xuejiao Li, Yuming Wang, Fangfang Zhang, Jiajia Duan

Get full text

Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

Get full text

Differentiation of high risk prostate cancer with a facile urinary exosome detection workflow by Shuai Qiu, Yue Li, Zheng Zhang, Chunchang Li, Haoyu Wang, Ao Chen, Zhi Yan, Yang Liu, Zifei Li, Hua Huang, Yi Liu, Yiqi Seow, Ruibing Chen, Jinhong Guo, Simeng Wen, Jing Tian, Hongtuan Zhang, Ranlu Liu, Gang Han, Baolong Wang, Yong Wang, Yuanjie Niu, HaiFang Yin

Get full text

NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression by Wenchao Xu, Jianzhou Liu, Qiaofei Liu, Jia Xu, Li Zhou, Zhiyong Liang, Haoran Huang, Bowen Huang, Gary Guishan Xiao, Junchao Guo

Get full text

Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti... by Arndt Borkhardt, Nan Qin, Stephen T Keir, Darell D Bigner, Allison Cole, Matthias Wölfl, Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Joselyn Cruz-Cruz, Claus M Graef, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Thomas Kurz, Marc Remke, Siddhartha Mitra

Get full text

Comprehensive Screening and Identification of Phillyrin Metabolites in Rats Based on UHPLC-Q-Exactive Mass Spectrometry Combined with Multi-Channel Data Mining by Beibei Ma, Jiameng Li, Tianyu Lou, Yaoyue Liang, Chenxiao Wang, Ruiji Li, Tingting Wang, Jinhui Liu, Yudong Guo, Zhibin Wang, Jing Wang

“…In summary, this study not only comprehensively explained the in vivo metabolism of phillyrin, but also proposed an effective strategy to quickly analyze and identify the metabolites of natural pharmaceutical ingredients in nature.…”
Get full text

The Mast Cell-Aryl Hydrocarbon Receptor Interplay at the Host-Microbe Interface by Claudio Costantini, Giorgia Renga, Vasilis Oikonomou, Giuseppe Paolicelli, Monica Borghi, Marilena Pariano, Antonella De Luca, Matteo Puccetti, Claudia Stincardini, Paolo Mosci, Andrea Bartoli, Teresa Zelante, Luigina Romani

Get full text

UPLC-MS metabolite profiling and antioxidant activity of Sanghuangporus sanghuang extract by Weike Wang, Na Lu, Cheng Jiang, Guanping Chen

“…Background The objective of the present study is to examine the total phenolic and flavonoid content of an ethanol extract of Sanghuangporus sanghuang and to evaluate its phytochemical properties, antioxidant activity, and capacity to protect DNA from damage. This pharmaceutical/food resource mushroom may serve as a novel substitute functional food for health-conscious consumers, given its promising source of phenolics and flavonoids. …”
Get full text

Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior by Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yu Takahashi, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara

Get full text

Fetuin-B and oxidative stress disrupt placental trophoblasts during maternal undernourishment by Mia Camilliere, Marella R. Verde, Michael S. Wolin, May M. Rabadi, Brian B. Ratliff

“…The effects of MUN and fetuin-B on mitochondrial superoxide production, antioxidant levels, metabolism, and electron transport chain complex activity were compared directly. Pharmaceutical interventions were utilised to narrow down specific pathways involved.Results Studies indicated that MUN and oxidative stress upregulated fetuin-B in the placenta. …”
Get full text

Microencapsulation of Essential Oils by Spray-Drying and Influencing Factors by Thi Thu Trang Nguyen, Thi Van Anh Le, Nhu Ngoc Dang, Dan Chi Nguyen, Phu Thuong Nhan Nguyen, Thanh Truc Tran, Quang Vinh Nguyen, Long Giang Bach, Dung Thuy Nguyen Pham

“…Furthermore, recent applications of encapsulated EOs in the fields of foods, pharmaceuticals, and textile industries are also thoroughly addressed.…”
Get full text

Evaluation of the EndoPAT as a Tool to Assess Endothelial Function by M. Moerland, A. J. Kales, L. Schrier, M. G. J. van Dongen, D. Bradnock, J. Burggraaf

“…Endothelial dysfunction is a potential target for (pharmaceutical) intervention of several systemic pathological conditions. …”
Get full text

Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review by Adekunle Babajide Rowaiye, Lorretha Chinonye Emenyonu, Ezinne Janefrances Nwonu, Okiemute Ajiroghene Okpalefe, Joseph Akwoba Ogugua, Victor Oluwatoyin Akinseye, Gordon Chukwuma Ibeanu

Get full text

Methotrexate for the Treatment of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation by Amr Nassar, Ghada Elgohary, Tusneem Elhassan, Zubeir Nurgat, Said Y. Mohamed, Mahmoud Aljurf

Get full text