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Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide
Published 2025-01-01“…Yizhuo Xie,1 Ming Zhu,1 Han Bao,1 Kejia Chen,1 Shanshan Wang,1 Jingwen Dai,1 Hongzhu Chen,1 He Li,1 Qi Song,2 Xinlu Wang,2 Liangping Yu,2 Jin Pei1 1Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People’s Republic of China; 2Department of Clinical Pharmacy, the First Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jin Pei, Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, People’s Republic of China, Tel +86-431-85619725, Email peijin@jlu.edu.cn Liangping Yu, Department of Clinical Pharmacy, the First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130061, People’s Republic of China, Tel +86 431 81879802, Email liangpingyu@jlu.edu.cnPurpose: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. …”
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2724
Efficient One-Pot Synthesis of Novel Caffeic Acid Derivatives as Potential Antimalarials
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2725
DNA Methylation and Chromatin Remodeling: The Blueprint of Cancer Epigenetics
Published 2016-01-01“…Therefore, cancer epigenetics, especially at a molecular level, needs to be scrutinised closely, as it could potentially serve as the future pharmaceutical goldmine against neoplastic diseases. However, in view of its rapidly enlarging scope of application, it has become difficult to keep abreast of scientific information coming out of various epigenetic studies directed against cancer. …”
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2726
Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity
Published 2021-01-01“…In the last two decades, quercetin has attracted considerable attention due to the biological and pharmaceutical activities such as antioxidant, antibacterial, and anticancer. …”
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2727
Liquid Chromatography-Tandem Mass Spectrometric Assay for Determination of Stavudine in Human Plasma
Published 2014-01-01“…A LC-MS/MS method for determination of stavudine in human plasma was established and validated, and it was applied to the pharmaceutical formulations bioequivalence study. 0.5 mL plasma sample was extracted by liquid-liquid extraction. …”
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2728
Biodegradable Polymers for Microencapsulation Systems
Published 2022-01-01“…The controlled release of encapsulated active agents is a research field that, over the years, has been constantly innovating due to the promising applications in the areas of pharmaceutical, cosmetic, textile industry, among others. …”
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Cell Therapy for Retinal Dystrophies: From Cell Suspension Formulation to Complex Retinal Tissue Bioengineering
Published 2019-01-01“…Another critical aspect described herein is the pharmaceutical formulation of the end product to be delivered into the eye of patients. …”
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Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis?
Published 2012-01-01“…Several gene therapy approaches and pharmaceutical treatments have been demonstrated to prolong the survival of pancreatic islet grafts in animal models; however, the clinical applications need to be investigated further. …”
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PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion
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Decision-making for supplier selection of supplement packaging
Published 2025-01-01“…This research was conducted on manufacturers of various pharmaceutical products in Indonesia, especially multivitamins and over-the-counter medicines, and focused on packaging, which also plays a significant role. …”
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Bioactive Fused Pyrazoles Inspired by the Adaptability of 5-Aminopyrazole Derivatives: Recent Review
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T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics
Published 2024-12-01“…The surge in the clinical use of therapeutic antibodies has reshaped the landscape of pharmaceutical therapy for many diseases, including rare and challenging conditions. …”
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Spectrophotometric Determination of Reboxetine through Condensation and Diazo-Coupling Reactions
Published 2011-01-01“…In the present study, two simple, sensitive and reproducible visible spectrophotometric methods were developed for the determination of reboxetine in pure form and in pharmaceutical formulations. The methods involve acid hydrolysis of reboxetine methane sulphonate (Reboxetine as methane sulphonate) and the product obtained was used for the estimation. …”
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Improvement of N-Acetylcysteine Loaded in PLGA Nanoparticles by Nanoprecipitation Method
Published 2018-01-01“…However, its use in the pharmaceutical industry, as a proper specific load vehicle, still depends on the improvement of the load capacity.…”
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Ensete ventricosum: A Multipurpose Crop against Hunger in Ethiopia
Published 2020-01-01“…Enset starch is found to have higher or comparable quality to potato and maize starch and widely used as a tablet binder and disintegrant and also in pharmaceutical gelling, drug loading, and release processes. …”
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