Neratinib as a Potential Therapeutic for Mutant RAS and Osimertinib-Resistant Tumours by Paul Dent, Laurence Booth, Andrew Poklepovic, John F. Hancock

“…Neratinib rapidly disrupted mutant RAS nanoclustering, which was followed by mutant rat sarcoma virus proteins translocating via LC3-associated phagocytosis into the cytosol where they were degraded by macroautophagy. …”
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Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

“…Macrophage TG content increased about 5-fold after incubation with CRLPw/o, and this effect was not reduced by the inhibition of phagocytosis, macropinocytosis, apolipoprotein E function, or proteoglycan bridging. …”
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Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria by Teresa Krakauer

“…Inflammasome, autophagy, and cell death pathways can be activated by pathogens, pathogen-associated molecular patterns (PAMPs), cell stress, and host-derived damage-associated molecular patterns (DAMPs). Phagocytosis and toll-like receptor (TLR) signaling induce reactive oxygen species (ROS), type I IFN, NFκB activation of proinflammatory cytokines, and the mitogen-activated protein kinase cascade. …”
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Administration of Rhodiola kirilowii Extracts during Mouse Pregnancy and Lactation Stimulates Innate but Not Adaptive Immunity of the Offspring by Sławomir Lewicki, Ewa Skopińska-Różewska, Aleksandra Brewczyńska, Robert Zdanowski

“…In addition, both types of Rhodiola kirilowii extracts stimulated granulocyte phagocytosis and increased level of respiratory burst. …”
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In Vivo Quantitative Measurement of Arthritis Activity Based on Hydrophobically Modified Glycol Chitosan in Inflammatory Arthritis: More Active than Passive Accumulation by Kyeong Soon Park, Jin Hee Kang, Keum Hee Sa, Hee Beom Koo, Hyun Jung Cho, Eon Jeong Nam, In Chan Youn, Kwang Meyung Kim, In San Kim, Ick Chan Kwon, Kui Won Choi, Young Mo Kang

“…Histologic evaluation confirmed that the mechanism underlying selective accumulation of HGC-Cy5.5 within synovitis tissues included enhanced phagocytosis of the probe by Mac-1-expressing macrophages as well as enhanced permeability through leaky vessels. …”
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A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy by Manqing Peng, Xiaofang Lu, Junshuang Guo, Xiangli Yin, Jing Zhang, Xin Li, Yizhou Zou

“…VISTA functions both as a ligand on myeloid cells, where it regulates cytokine production, chemotaxis, and phagocytosis while promoting their differentiation into a tolerogenic phenotype and as a receptor on T cells, where it contributes to T cell quiescence. …”
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Reduced PKC α Activity Induces Senescent Phenotype in Erythrocytes by Rukmini B. Govekar, Poonam D. Kawle, Suresh H. Advani, Surekha M. Zingde

“…The erythrocytes with these surface modifications undergo macrophage-mediated phagocytosis. In this study, the role of protein kinase C (PKC) isoforms in the expression of these surface modifications was investigated. …”
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Mechanisms and roles of membrane-anchored ATG8s by Soo-Kyeong Lee, Sang-Won Park, Deok-Jin Jang, Jin-A. Lee

“…However, recent studies have identified non-canonical roles for lipidated ATG8 in processes such as LC3-associated phagocytosis (LAP), LC3-associated endocytosis (LANDO), and lipidated ATG8-mediated secretory autophagy. …”
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Ubiquitination of CD47 Regulates Innate Anti‐Tumor Immune Response by Qian Gou, Bingjun Yan, Yalan Duan, Yilei Guo, Jing Qian, Juanjuan Shi, Yongzhong Hou

“…Here it is found that TRAF2 bound to the C‐terminal of CD47 cytoplasmic fragment and induced its ubiquitination, leading to inhibition of CD47 autophagic degradation by disrupting its binding to LC3, which in turn inhibited macrophage phagocytosis and promoted tumor immune escape. In contrast, loss of TRAF2 facilitated CD47 autophagic degradation and inhibited tumor immune escape. …”
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Caveolin-Mediated Endocytosis: Bacterial Pathogen Exploitation and Host–Pathogen Interaction by Dibyasri Barman, Rishi Drolia

“…Within mammalian cells, diverse endocytic mechanisms, including phagocytosis, pinocytosis, and receptor-mediated endocytosis, serve as gateways exploited by many bacterial pathogens and toxins. …”
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Analysis of the effect of ALA-PDT on macrophages in footpad model of mice infected with Fonsecaea monophora based on single-cell sequencing by Chen Wenyi, Wu Xuelin, Yaqoob Muhammad Danish, Liu Kangxing, Hu Yanqing, Ke Xiuling, Hu Yongxuan

“…After ALA-PDT treatment, the number of inflammatory cells decreased, while macrophages upregulated the expression of antigen-recognition-related genes, enhancing phagocytosis and autophagy-related biological functions.…”
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右美托咪定受体依赖性增强巨噬细胞吞噬功能 by 吴珊, 罗刚健, 姚伟锋, 蔡珺, 黑子清

“…Western blotting检测α2A肾上腺素受体、p-Akt、Akt的表达，Phagocytosis Assay Kit（IgG PE）检测巨噬细胞的吞噬能力。【结果】RAW264.7细胞上有α2A肾上腺素受体的表达；右美托咪定能够增强巨噬细胞的吞噬能力（P<0.001），BRL44408逆转巨噬细胞吞噬能力的增强（P<0.001）；右美托咪定使RAW264.7细胞的Akt通路激活，BRL44408的使用抑制Akt通路的激活（P<0.01）。…”
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The Immunotherapeutic Effect of SIRPα-Silenced DCs against Cervical Cancer by Xiaojie Li, Wenying Zhou, Yanlan Liang, Changzhi Xu, Zhizhi Xie, Jiayin Liang, Bo Hu

“…The interaction between SIRPα and CD47 leads to a negative signal that prevents the phenotypic and functional maturation of DC and inhibits phagocytosis. The SIRPα knockdown in DCs that were pulsed with a modified HPV16E7 (HPV16mE7) protein with enhanced antigenicity and reduced transformation activity results in increased cytokine (TNF-α/IL-12/IL-6) secretion, IFN-γ secretion by T lymphocytes, and in vitro/in vivo tumoricidal activity against cervical cancer cells. …”
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Ways to promote the efficiency of herpetic stomatitis treatment by R.V. Lutsenko, N.V. Moisieieva, A.H. Sydorenko, H.Yu. Ostrovska, A.A. Kapustianska

“…The drug suppresses the synthesis of the virus due to the structure of inosinic acid in the polyribosomes of the cell affected by the virus, and also helps to eliminate the deficiency or dysfunction of immunity that occurred in the case of herpetic stomatitis, it affects the activity of T-cytotoxic lymphocytes and natural killers, enhances the action of neutrophil granulocytes, chemotaxis and phagocytosis of monocytes and macrophages, increases the synthesis of interleukins IL-1 and IL-2, affects the number of Ig G immunoglobulins. …”
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Trogocytosis-mediated immune evasion in the tumor microenvironment by Jeonghyun Kim, Soyeon Park, Jungseo Kim, Yewon Kim, Hong Min Yoon, Bima Rexa Rayhan, Jaekwang Jeong, Alfred L. M. Bothwell, Jae Hun Shin

“…Abstract Trogocytosis is a dynamic cellular process characterized by the exchange of the plasma membrane and associated cytosol during cell-to-cell interactions. Unlike phagocytosis, this transfer maintains the surface localization of transferred membrane molecules. …”
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Differences in the Antigens of Helicobacter pylori Strains Influence on the Innate Immune Response in the In Vitro Experiments by Miha Skvarc, Andreja Natasa Kopitar, Janko Kos, Natasa Obermajer, Bojan Tepes

“…Differences in lipid A of H. pylori might have an influence on the insufficient immune response, especially on phagocytosis.…”
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Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness by Ryley S. Crow, Leon Grayfer, L. Courtney Smith

“…Other rSpTrf proteins cross-linked to inert beads show distinct functions for cell binding and augmenting phagocytosis . However, whether the rSpTrf proteins bind to sea urchin phagocytes, and the cellular consequences of binding are largely unexplored. …”
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Role of CD117 and mast cells in periodontal diseases: Histological and immunohistochemical study by Fatin L. Khaphi, Hanaa Ali Hussein, Oula Fouad Hameed, Huda Jassem Jebur, Zahra Kadhum Saeed

“…Mast cells are mobile secretory cells with a variety of biological tasks such as phagocytosis, processing of antigens, cytokine production, and the release of both newly formed and preexisting physiological mediators. …”
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lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases by Lulingxiao Nie, Peng Zhang, Qian Wang, Xinyi Zhou, Qi Wang

“…Among macrophages, this phenomenon potentially impairs its immunosurveillance and phagocytosis mechanisms, leading to decreased recognition and clearance of malignant and senescent cells. …”
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AMINOSELETON-BASED CORRECTION OF IMMUNE STATUS IN WHITE RATS VACCINATED FROM SALMONELLOSIS AND CHRONICALLY EXPOSED TO T-2 TOXIN by S. V. Shabunin, A. G. Shakhov, G. A. Vostroilova, L. Yu. Sashnina, Yu. A. Kantarovich, Ye. V. Mikhailov, I. S. Tolkachev, Ye. V. Tyurina

“…It is related to active formation of neutrophils in the marrow and their further migration to the blood circulation system for phagocytosis. The detected morphological changes in blood of the vaccinated and exposed animals suggest hematological disorder associated with T-2 toxicosis demonstrated as erythropoiesis inhibition and leucopenia. …”
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