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Antibiofilm of metabolites of the Proteus myxofaciens JB 20B for the prevention and treatment of vaname shrimp infected with Vibrio harveyi bacteria
Published 2025-01-01“…Examining clinical symptoms, viewing histology, assessing total haemocyte count, phagocytosis activity, phenoloxidase activity, respiratory burst, and growth performance. …”
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62
Microglia Play a Major Role in Direct Viral-Induced Demyelination
Published 2013-01-01“…Our results suggest that MHV can directly infect and activate microglia during acute inflammation, which in turn during chronic inflammation stage causes phagocytosis of myelin sheath leading to chronic inflammatory demyelination.…”
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63
Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation
Published 2025-01-01“…Sialylated Trem2-FL (Sia-Trem2-FL) does not hinder Trem2-FL-DAP12-Syk complex assembly but impairs signal transduction through Syk, ultimately abolishing Trem2-dependent phagocytosis. Concurrently, Trem2-CTF-DAP12 complexes dampen NF-κB signaling, while sTrem2 propagates Akt-dependent cell survival and NFAT1-mediated production of TNF-α and CCL3. …”
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64
Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know
Published 2015-01-01“…Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in the bone marrow by activated macrophages. …”
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65
Rabs, Rips, FIPs, and Endocytic Membrane Traffic
Published 2003-01-01“…Rab11 GTPase, a member of the Rab protein family, plays a role in regulating various cellular functions, including plasma membrane recycling, phagocytosis, and cytokinesis. Rab11 acts by forming mutually exclusive complexes with Rab11-family binding proteins, known as FIPs. …”
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66
IgE-mediated histamine release from nasal mucosa is inhibited by SLPI (secretory leukocyte protease inhibitor) to the level of spontaneous release
Published 1998-01-01“…The secretory leukocyte protease inhibitor (SLPI) is a low-molecular-weight inhibitor of proteases, such as elastase and cathepsin G which are released from leukocytes during phagocytosis. The purpose of this study was to determine whether or not SLPI is able to inhibit IgE-mediated histamine release. …”
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67
Mitochondria-Associated Endoplasmic Reticulum Membranes in Microglia: One Contact Site to Rule Them all
Published 2025-01-01“…Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in maintaining tissue homeostasis by monitoring and responding to environmental changes through processes such as phagocytosis, cytokine production or synapse remodeling. …”
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68
Biochemistry of the Phagosome: The Challenge to Study a Transient Organelle
Published 2011-01-01“…Intracellular granules or lysosomes of the phagocyte fuse with the phagosome and liberate their destructive enzymes. This process of phagocytosis efficiently protects against most infections; however, some microorganisms avoid their destruction and cause severe damage. …”
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69
Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning
Published 2012-01-01“…These changes were suppressed by GdCl3 treatment prior to T3, an agent-eliciting Kupffer-cell depletion, inhibition of colloidal carbon phagocytosis, and the associated respiratory burst activity, with enhancement in nuclear inhibitor of Nrf2 kelch-like ECH-associated protein 1 (Keap1)/Nrf2 content ratios suggesting Nrf2 degradation. …”
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70
Pulmonary surfactant system
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71
Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions
Published 2010-01-01“…This review focuses on how these two protein families contribute to migration, phagocytosis, and reactive oxygen species production, as well as their epistatic and feedback relations that finely tune these crucial aspects of the immune response.…”
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72
Bacteria--phagocyte dynamics,axiomatic modelling and mass-action kinetics
Published 2011-03-01“…It is shown that other commonly used models that do not belong to this class may miss important features that are associated with the limited growth curve of thebacteria (prey) and the saturationassociated with the phagocytosis (predator kill) term. Notably, these features appear at relatively low concentrations, much below the saturation range. …”
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73
Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells
Published 2025-01-01“…<b>Results</b>: The iPSC-derived macrophages generated through this method exhibit characteristic features and cell marker proteins, as well as classical macrophage activities, including lipoprotein uptake, bacterial phagocytosis, cytokine release, and inflammasome activation. …”
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74
Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils
Published 2025-02-01“…In contrast, neutrophils exposed to non-citrullinated vimentin exhibited higher efficiency in favoring pathogen phagocytosis, such as Escherichia coli and Candida albicans, compared to CitVim. …”
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75
The Antioxidant Effect of Erythropoietin on Thalassemic Blood Cells
Published 2010-01-01“…This resulted in reduced susceptibility of RBC to undergo hemolysis and phagocytosis. Injection of Epo into heterozygous (Hbbth3/+) β-thalassemic mice reduced the oxidative markers within 3 hours. …”
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76
The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties
Published 1996-01-01“…The subcutaneous injection of the venom, or its addition to cell cultures, had an inhibitory effect on the spreading and phagocytosis of resident macrophages, without affecting the viability of the cells. …”
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77
Systematic analysis of Fc mutations designed to enhance binding to Fc-gamma receptors
Published 2024-12-01“…We have now produced a matched set of anti-CD20 antibodies representing a range of variants and compared their activity in cell-based assays for complement-dependent cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and antibody-dependent phagocytosis using a range of individual Fc receptors. …”
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78
Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers
Published 2023-06-01“…Importantly, we observed that the BG34-200-CD11b engagement triggered endocytosis of the binding complexes in TAIMs, which induced intracellular F-actin cytoskeletal rearrangement, effective phagocytosis, and intrinsic ICAM-1 (intercellular adhesion molecule I) clustering. …”
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79
Sjogren’s Syndrome and TAM Receptors: A Possible Contribution to Disease Onset
Published 2019-01-01“…Receptor tyrosine kinases (RTKs) of the Tyro3, Axl, and Mer (TAM) family are present on the surface of macrophages and dendritic cells and participate in phagocytosis of apoptotic cells (efferocytosis) and inhibition of Type I IFN signaling. …”
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80
Antioxidant Functions of Nitric Oxide Synthase in a Methicillin Sensitive Staphylococcus aureus
Published 2013-01-01“…The SaNOS mutant also showed reduced survival after phagocytosis by PMN cells with respect to wild-type S. aureus.…”
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