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Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ
Published 2025-01-01Subjects: Get full text
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42
PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macrophage progeny
Published 2025-02-01“…Directing p50-IMC to tumors using Fc receptor-bound antibodies (Abs) or surface chimeric antigen receptors (CARs) may increase tumor localization and subsequent phagocytosis of cancer cells by their mature myeloid progeny, potentiating anti-tumor T cell activation. …”
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Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy Based on the Silencing of Proinflammatory G-Protein Coupled Kinin B2 and B1 Receptors
Published 2014-01-01Get full text
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<i>In vitro</i> assay of biological activity of a national preparation of macrophage activating factor (GcMAF-RF)
Published 2020-05-01Subjects: Get full text
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45
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation
Published 2023-01-01“…Finally, combining CI-994 treatment with an anti-CD47 mAb targeting the CD47-SIRPα phagocytosis checkpoint enhanced in vitro phagocytosis and survival in tumor-bearing mice.Conclusion Together, these findings suggest a dynamic relationship between MYC amplification and innate immune suppression in MYC amplified MB and support further investigation of phagocytosis modulation as a strategy to enhance cancer immunotherapy responses.…”
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Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency
Published 2025-02-01“…Previous studies demonstrated that high, rather than low α-defensin level could modulate the local pro-inflammatory milieu of bronchial epithelial cells and macrophages promoting chronic inflammation and lower pathogen phagocytosis. IgG-mediated phagocytosis and NTHi adherence, engulfment and phagocytosis were measured in human alveolar macrophages and monocyte-derived macrophages (MDM) isolated from patients with AATD and from healthy individuals. …”
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Carbon Black Particle Exhibits Size Dependent Toxicity in Human Monocytes
Published 2014-01-01“…The parameters like MTT assay, phagocytosis assay, ELISA, gene expression, and DNA analysis were studied. …”
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48
Suppression of monocyte and neutrophil function by recombinant IL-2
Published 1993-01-01“…We now describe the effects of human recombinant IL-2 on human neutrophil and monocyte functions related to mobility, phagocytosis, glucose uptake, respiration and degranulation. …”
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49
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons
Published 2025-01-01“…Summary: The elimination of superfluous neurons via apoptosis and subsequent glial phagocytosis is crucial for the development of the central nervous system (CNS). …”
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50
Macrophage MST1 protects against schistosomiasis-induced liver fibrosis by promoting the PPARγ-CD36 pathway and suppressing NF-κB signaling.
Published 2024-12-01“…Mechanistically, MST1 activation by soluble egg antigen (SEA) promoted PPARγ-mediated CD36 expression, enhancing phagocytosis and consequently upregulation of fibrolytic genes such as Arg1 and Mmps. …”
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51
Coelomocytes: Biology and Possible Immune Functions in Invertebrates with Special Remarks on Nematodes
Published 2009-01-01“…They are involved in important immune functions, such as phagocytosis, encapsulation, graft rejection, and inflammation, as well as the synthesis and secretion of several humoral factors especially in annelids and echinoderms. …”
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Low-Dose Oxygen Enhances Macrophage-Derived Bacterial Clearance following Cigarette Smoke Exposure
Published 2016-01-01“…In culture, macrophages exposed to cigarette smoke and oxygen also demonstrated decreased TNF-α secretion and enhanced phagocytosis of PAO1 bacteria. Conclusions. Our findings demonstrate a novel, protective role for low-dose oxygen following cigarette smoke and bacteria exposure that may be mediated by enhanced macrophage phagocytosis.…”
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Effects of the Bacterial Extract OM-85 on Phagocyte Functions and the Stress Response
Published 1994-01-01“…Activation of the respiratory burst during bacterial phagocytosis has been previously associated with heat shock/stress proteins synthesis. …”
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Saving Death: Apoptosis for Intervention in Transplantation and Autoimmunity
Published 2006-01-01“…In that regard, recent evidence suggests that phagocytosis of apoptotic cells by DCs can induce Tregs, a finding that has significant implications for the treatment of a variety of immune-mediated inflammatory disorders. …”
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Different Modulating Effects of Adenosine on Neonatal and Adult Polymorphonuclear Leukocytes
Published 2012-01-01“…Intact PMN functions include adhesion, migration, phagocytosis, and reactive oxygen species (ROS) release. …”
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Vesicles Generated during Storage of Red Blood Cells Enhance the Generation of Radical Oxygen Speciesin Activated Neutrophils
Published 2011-01-01“…Fluorescentlylabeled Vsto and calcium-induced vesicles were preparedin order to study the uptake of labeled vesicular components by neutrophils as compared to the process of phagocytosis of zymosan using flow cytometry and confocal microscopy. …”
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Severe Inflammation Caused by Coinfection of PCV2 and Glaesserella parasuis Is Associated with Pyroptosis via Noncanonical Inflammasome Pathway
Published 2022-01-01“…Coinfection with PCV2 and G. parasuis can enhance RAW264.7 cell phagocytosis and elimination to G. parasuis. Cell death rate of cells increased in coinfection was measured with Flow cytometry. …”
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In vitro triazophos suppresses innate and cell-mediated immune responses of lymphoid organs in snakehead fish, Channa punctatus
Published 2025-06-01“…Additionally, triazophos suppressed the phagocytosis by lymphoid organ cells in a dose-dependent manner. …”
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Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance.
Published 2025-01-01“…Moreover, Pg were predominantly phagocytosed by macrophages, and gingipain depletion/inactivation increased bacterial phagocytosis when bacteria were injected either systemically or locally in the otic vesicle, with less bacteria internalised by neutrophils. …”
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Pengaruh Pemberian Glutamin pada Kemampuan Fagositosis Makrofag terhadap Pseudomonas Aeruginosa
Published 2015-09-01“…That seein it percentage of phagocytosis against P. aeruginosa smaller than compared to latex. …”
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