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161
Catalysts of change: Immunotherapy's frontier in oral oncology
Published 2024-09-01“…The future focus is on personalized medicine and innovative therapeutic strategies, with the goal of maximizing the effectiveness of therapy and improving patient outcomes in the management of oral cancer. …”
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162
Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning
Published 2024-01-01“…Recognizing the potential of personalized medicine, this research underscores the need for a comprehensive understanding of asthma’s immunological diversity. …”
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163
In silico modelling of organ-on-a-chip devices: an overview
Published 2025-01-01“…Diverse OOAC devices specific to different organs have been proposed for experimental research and applications such as disease modelling, personalized medicine and drug screening. Previous studies have demonstrated that the mathematical modelling of OOAC can facilitate the optimization of chips’ microenvironments, serving as an essential tool to design and improve microdevices which allow reproducible growth of cell culture, reducing the time and cost of experimental testing. …”
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164
Responsive afatinib treatment in high-grade salivary gland ductal carcinoma and NSCLC with uncommon EGFR mutations: Treatment outcomes
Published 2024-06-01“…The success of afatinib in both malignancies underscores the importance of personalized medicine. Targeting specific genetic alterations with afatinib offers tailored treatment strategies, potentially improving outcomes and quality of life. …”
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165
Microfluidic Nanoparticle Separation for Precision Medicine
Published 2025-01-01“…As nanoparticles, both of biological origin and for therapeutic purposes, become increasingly important in precision medicine, microfluidic nanoparticle separation proves particularly advantageous for handling valuable samples in personalized medicine. This technology not only enhances detection, diagnosis, monitoring, and treatment accuracy, but also reduces invasiveness in medical procedures. …”
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166
Stem cells for age-related macular degeneration
Published 2019-09-01“…</i> </p> <p> <i><sup>2</sup>Institute for Molecular and Personalized Medicine. 7, Build. 2, 2<sup>nd</sup> Botkinskiy Pass., Moscow, 125284, Russian Federation.…”
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167
Connecting electronic health records to a biomedical knowledge graph to link clinical phenotypes and molecular endotypes in atopic dermatitis
Published 2025-01-01“…To succeed in providing personalized medicine to patients, it will be necessary to integrate medical, biological and molecular data in order to identify all complex disease subtypes and understand their pathobiological mechanism. …”
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168
Functional genomic imaging (FGI), a virtual tool for visualization of functional gene expression modules in heterogeneous tumor samples
Published 2025-01-01“…Our results highlight the potential of FGI as a robust visualization tool for personalized medicine in molecular diagnosis.…”
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169
Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases
Published 2025-01-01“…Additionally, we address current challenges, including biocompatibility, scalability, and regulatory hurdles, as well as future directions for integrating advanced nanotechnology with personalized medicine in autoimmune treatment. This review highlights the transformative potential of biodegradable and stimuli-responsive nanomaterials, presenting them as a promising strategy to advance precision medicine and improve patient outcomes in autoimmune disease management.…”
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170
Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
Published 2025-01-01“…The review also highlights emerging research areas benefiting from AI, including personalized medicine and synthetic biology. The methodology involves an extensive analysis of existing literature, particularly peer-reviewed studies on AI applications in biochemistry. …”
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171
A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
Published 2025-03-01“…., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. …”
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172
Personalized Injury Reduction Strategies in Sports Medicine: Lessons Learned from Advances in Breast Cancer Treatment: A Clinical Commentary
Published 2023-02-01“…# Key Results Breast cancer mortality has consistently decreased over the last 30 years, largely attributed to advances in personalizing the prevention and treatment strategies which include modifiable and non-modifiable factors when assessing risk, the transition to personalized medicine, and the systematic approach used to investigate individual risk factors. …”
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173
BCL-2 inhibitors in hematological malignancies: biomarkers that predict response and management strategies
Published 2025-01-01“…Finally, we focus on the biomarkers that can be used to predict responses to treatment in the name of personalized medicine, with the goal of exploring alternative strategies to overcome resistance.…”
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174
A systematic review of progress test as longitudinal assessment in Saudi Arabia
Published 2025-01-01“…It identifies areas for improvement and informs the development of more effective assessment methods that better prepare future doctors for a future of innovation and personalized medicine.…”
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175
Molecular insights into the unique properties of the blood‐circulating proteasome
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176
In situ minimally invasive 3D printing for bone and cartilage regeneration - a scoping review
Published 2024-09-01“…Advancements in personalized medicine, threedimensional (3D) printing, miniaturization, and robot-assisted surgery are driving innovation in tissue engineering. …”
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177
Personalized Organoid-Based Treatments in Older Patients with Cancer: A Registry Study in Progress
Published 2024-10-01“…Organoid technology has emerged as a promising frontier in cancer treatment, offering a versatile platform for personalized medicine and drug development. By recapitulating the three-dimensional (3D) architecture, cell-matrix interactions and tissue heterogeneity, organoid cultures provide an accurate representation of individual tumor properties, thus enabling the precise modeling of tumor behavior. …”
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178
Unlocking biological complexity: the role of machine learning in integrative multi-omics
Published 2024-11-01“…This approach paves the way for personalized medicine by identifying unique molecular signatures for individual patients, which can provide valuable insights into treatment planning and support more effective treatment. …”
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179
Proteomics and Its Current Application in Biomedical Area: Concise Review
Published 2024-01-01“…In addition, it plays a pivotal role in drug discovery and the emerging frontier of personalized medicine. The versatility of proteomics allows researchers to delve into the intricacies of molecular mechanisms, paving the way for innovative therapeutic approaches. …”
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180
Limitations of Separating Athletes into High or Low-Risk Groups based on a Cut-Off. A Clinical Commentary
Published 2024-09-01“…Using continuous variables on its original scale is advantageous because information is not discarded, outcome prediction accuracy is not lost, and personalized medicine can be facilitated. # Clinical Application Researchers and clinicians are encouraged to analyze and interpret the results of tests and measures using continuous variables and avoid relying on singular cut-offs to guide decisions. …”
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