Ultra-sensitive fluorescence-activated droplet single-cell sorting based on Tetramer-HCR-EvaGreen amplification by Long Chen, Yi Xu, Lele Zhou, Ding Ma, Rong Zhang, Yifan Liu, Xianqiang Mi

“…The established THE-FADS showed the promising prospects to cellular heterogeneity understanding and personalized medicine.…”
Get full text

Generation of a human induced pluripotent stem cell (iPSC) line ERPLi004-A from an Alpha-1 antitrypsin deficiency (AATD) patient with SERPINA1 mutation by Harshini Surendran, Rajani Battu, Renjitha Gopurappilly, Chethala N. Vishnuprasad, Rajarshi Pal

“…The iPSC line expresses pluripotency markers, generates three germ layers in vitro and retains a normal karyotype (P20) and can provide an ideal tool for disease modelling, drug screening, and personalized medicine.…”
Get full text

Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application by Matthias S. Klein, Jane Shearer

“…As a result, metabolomics has the potential to enable informed decision-making in the realm of personalized medicine.…”
Get full text

Evolution of tick vaccinology by José de la Fuente, Srikant Ghosh, Ala Tabor

“…Future directions will advance in these areas together with other novel technologies such as multiomics, AI and Big Data, mRNA vaccines, microbiota-driven probiotics and vaccines, and combination of vaccines with other interventions in collaboration with regions with high incidence of tick infestations and tick-borne diseases for a personalized medicine approach.…”
Get full text

Digital Health Innovations to Catalyze the Transition to Value-Based Health Care by Lan Zhang, Christopher Bullen, Jinsong Chen

“…Digital health, which includes mobile health, wearable devices, telehealth, and personalized medicine, shows promise in improving diagnostic accuracy, treatment options, and overall health outcomes. …”
Get full text

The Growing Challenge of Chronic Kidney Disease: An Overview of Current Knowledge by Rikke Borg, Nicholas Carlson, Jens Søndergaard, Frederik Persson

“…In the future, more precise and less invasive diagnostic methods may not only improve the determination of the underlying cause of CKD but may also carry information regarding which treatment to use (i.e. personalized medicine). This could lead to a reduced number of preventive treatments per individual, while at the same time improving the prognosis. …”
Get full text

Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…Recognizing the potential of personalized medicine, this research underscores the need for a comprehensive understanding of asthma’s immunological diversity. …”
Get full text

In silico modelling of organ-on-a-chip devices: an overview by Yue Wang, Lucia Marucci, Lucia Marucci, Lucia Marucci, Martin E. Homer

“…Diverse OOAC devices specific to different organs have been proposed for experimental research and applications such as disease modelling, personalized medicine and drug screening. Previous studies have demonstrated that the mathematical modelling of OOAC can facilitate the optimization of chips’ microenvironments, serving as an essential tool to design and improve microdevices which allow reproducible growth of cell culture, reducing the time and cost of experimental testing. …”
Get full text

Microfluidic Nanoparticle Separation for Precision Medicine by Zhenwei Lan, Rui Chen, Da Zou, Chun‐Xia Zhao

“…As nanoparticles, both of biological origin and for therapeutic purposes, become increasingly important in precision medicine, microfluidic nanoparticle separation proves particularly advantageous for handling valuable samples in personalized medicine. This technology not only enhances detection, diagnosis, monitoring, and treatment accuracy, but also reduces invasiveness in medical procedures. …”
Get full text

Connecting electronic health records to a biomedical knowledge graph to link clinical phenotypes and molecular endotypes in atopic dermatitis by Francesca Frau, Paul Loustalot, Margaux Törnqvist, Nina Temam, Jean Cupe, Martin Montmerle, Franck Augé

“…To succeed in providing personalized medicine to patients, it will be necessary to integrate medical, biological and molecular data in order to identify all complex disease subtypes and understand their pathobiological mechanism. …”
Get full text

Functional genomic imaging (FGI), a virtual tool for visualization of functional gene expression modules in heterogeneous tumor samples by Xinlei Chen, Youbing Guo, Xiaorong Gu, Danyi Wen

“…Our results highlight the potential of FGI as a robust visualization tool for personalized medicine in molecular diagnosis.…”
Get full text

Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases by Nargish Parvin, Sang Woo Joo, Tapas K. Mandal

“…Additionally, we address current challenges, including biocompatibility, scalability, and regulatory hurdles, as well as future directions for integrating advanced nanotechnology with personalized medicine in autoimmune treatment. This review highlights the transformative potential of biodegradable and stimuli-responsive nanomaterials, presenting them as a promising strategy to advance precision medicine and improve patient outcomes in autoimmune disease management.…”
Get full text

A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things by Pit Hofmann, Juan A. Cabrera, Gunnar Schulte, Frank H.P. Fitzek

“…., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. …”
Get full text

Personalized Injury Reduction Strategies in Sports Medicine: Lessons Learned from Advances in Breast Cancer Treatment: A Clinical Commentary by Garrett Bullock, Gary Collins, Rober Adams, Charles Thigpen, Ellen Shanley

“…# Key Results Breast cancer mortality has consistently decreased over the last 30 years, largely attributed to advances in personalizing the prevention and treatment strategies which include modifiable and non-modifiable factors when assessing risk, the transition to personalized medicine, and the systematic approach used to investigate individual risk factors. …”
Get full text

BCL-2 inhibitors in hematological malignancies: biomarkers that predict response and management strategies by Mariam Markouli, Maria N. Pagoni, Panagiotis Diamantopoulos

“…Finally, we focus on the biomarkers that can be used to predict responses to treatment in the name of personalized medicine, with the goal of exploring alternative strategies to overcome resistance.…”
Get full text

A systematic review of progress test as longitudinal assessment in Saudi Arabia by Naseel Ahmed Moursy, Khaled Hamsho, Arwa Mohammad Gaber, Muhammad Faisal Ikram, Muhammad Raihan Sajid

“…It identifies areas for improvement and informs the development of more effective assessment methods that better prepare future doctors for a future of innovation and personalized medicine.…”
Get full text

Molecular insights into the unique properties of the blood‐circulating proteasome by Yegor Leushkin, David Morgenstern, Shifra Ben‐Dor, Rebecca Haffner‐Krausz, Katharina Zittlau, Gili Ben‐Nissan, Michal Sharon

Get full text

In situ minimally invasive 3D printing for bone and cartilage regeneration - a scoping review by Maintz Michaela, Tomooka Yukiko, Eugster Manuela, Gerig Nicolas, Sharma Neha, Thieringer Florian M., Rauter Georg

“…Advancements in personalized medicine, threedimensional (3D) printing, miniaturization, and robot-assisted surgery are driving innovation in tissue engineering. …”
Get full text

Unlocking biological complexity: the role of machine learning in integrative multi-omics by Ravindra Kumar, Rajrani Ruhel, Andre J. van Wijnen

“…This approach paves the way for personalized medicine by identifying unique molecular signatures for individual patients, which can provide valuable insights into treatment planning and support more effective treatment. …”
Get full text

Proteomics and Its Current Application in Biomedical Area: Concise Review by Semira Gobena, Bemrew Admassu, Mebrie Zemene Kinde, Abebe Tesfaye Gessese

“…In addition, it plays a pivotal role in drug discovery and the emerging frontier of personalized medicine. The versatility of proteomics allows researchers to delve into the intricacies of molecular mechanisms, paving the way for innovative therapeutic approaches. …”
Get full text