Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential by Ines Hadrich, Mariem Turki, Mariem Turki, Imen Chaari, Imen Chaari, Balkiss Abdelmoula, Rahma Gargouri, Nahed Khemakhem, Dhawia Elatoui, Fatma Abid, Sonda Kammoun, Sonda Kammoun, Mona Rekik, Mona Rekik, Samir Aloulou, Samir Aloulou, Mariem Sehli, Mariem Sehli, Aymen Ben Mrad, Aymen Ben Mrad, Sourour Neji, Fabian M. Feiguin, Jihene Aloulou, Jihene Aloulou, Nouha Bouayed Abdelmoula, Hayet Sellami, Hayet Sellami

“…Future research should integrate multi-omics approaches to unravel the complex interkingdom interactions within the gut ecosystem, paving the way for personalized medicine in mental health care.…”
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Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study by Marie-Angélique Cazalis, Marie-Angélique Cazalis, Louis Kreitmann, Louis Kreitmann, Guillaume Monneret, Guillaume Monneret, Alexandre Pachot, Alexandre Pachot, Karen Brengel-Pesce, Karen Brengel-Pesce, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos

“…In combination with lactate, this novel biomarker strategy may be useful for sepsis patient stratification for personalized medicine trials and ICU management.…”
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Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

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A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions by Jun Sun, Masanori Aikawa, Hassan Ashktorab, Noam D. Beckmann, Noam D. Beckmann, Michael L. Enger, Joaquin M. Espinosa, Xiaowu Gai, Xiaowu Gai, Benjamin D. Horne, Benjamin D. Horne, Paul Keim, Paul Keim, Paul Keim, Jessica Lasky-Su, Rebecca Letts, Cheryl L. Maier, Meisha Mandal, Lauren Nichols, Nadia R. Roan, Nadia R. Roan, Mark W. Russell, Jacqueline Rutter, George R. Saade, George R. Saade, Kumar Sharma, Kumar Sharma, Stephanie Shiau, Stephen N. Thibodeau, Samuel Yang, Lucio Miele, NIH Researching COVID to Enhance Recovery (RECOVER) Consortium

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Development of a computational model of glucose toxicity in the progression of diabetes mellitus by Danilo T. Pérez-Rivera, Verónica L. Torres-Torres, Abraham E. Torres-Colón, Mayteé Cruz-Aponte

“…One large stride that is being made is the generation of techniques to assist physicians to ``personalize medicine''.From available physiological data, biological understanding of the system, and dimensional analysis, a differential equation-based mathematical model was built in a sequential matter, to be able to elucidate clearly how each parameter correlates to the patient's current physiological state. …”
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Hot melt extrusion assisted additive manufacturing of mixed polymeric 3D printed metoprolol succinate extended-release tablets for controlled oral drug delivery by Shubham Ghatole, Jannu Dilip, Makka Krupali Ashokbhai, Himanshu Vishwakarma, Subham Banerjee, Santanu Kaity

“…This developmental pathway can also be used for the fabrication of personalized medicines with adjustable drug release profiles.…”
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Nano-technological advancements in multimodal diagnosis and treatment by Dinesh Bhatia, Tania Acharjee, Shruti Shukla, Monika Bhatia

“…This nanotechnology-based technique personalizes medicines for diseases such as tuberculosis (TB) and cardiovascular disease (CVD), focusing on damaged tissues to improve therapeutic response. …”
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The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders by Sean D. Fraser, Sean D. Fraser, Robert J. Harvey, Robert J. Harvey

“…We also highlight potential future developments in the field, including routes to personalized medicines for individuals with GlyR α2 mutations.…”
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