Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling by Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D. Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

“…Abstract Macrophages express numerous G protein-coupled receptors (GPCRs) that regulate adhesion, migration, and activation, but the function of orphan receptor GPRC5B in macrophages is unknown. Both resident peritoneal and bone marrow-derived macrophages from myeloid-specific GPRC5B-deficient mice show increased migration and phagocytosis, resulting in improved bacterial clearance in a peritonitis model. …”
Get full text

High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response by Tianzhu Tao, Lulong Bo, Teng Li, Longbao Shi, Hui Zhang, Bo Ye, Yuhai Xu, Qingqing Ma, Xiaoming Deng, Guorong Zhang

“…VISTA was substantially expressed on T cells and macrophages in sham-operated mice; septic peritonitis did not induce significant changes in the expression profiles. …”
Get full text

Causes and Clinical Profiles of Ascites at University of Gondar Hospital, Northwest Ethiopia: Institution-Based Cross-Sectional Study by Oumer Abdu Muhie

“…Five (20.8%) CLD patients had spontaneous bacterial peritonitis as a complication. Five (20.8%) and 4 (16.7%) CLD patients had hepatocellular carcinoma and hepatic encephalopathy as complications, respectively. …”
Get full text

Association of Pneumatosis Intestinalis With Surgical Outcomes and Mortality: A Matched, Retrospective Cohort Study and Literature Review by Kyle D. Klingbeil, MD, MS, Hila Zelicha, PhD, RD, Yijun Chen, MD, Douglas S. Bell, MD, Edward H. Livingston, MD, FACS, AGAF

“…Most patients underwent surgery for peritonitis (37%), bowel obstruction (31%), and/or pneumoperitoneum (23%) in association with PI; whereas only 8% of patients received surgery exclusively for PI. …”
Get full text

Formación de la competencia promoción y prevención en las complicaciones de la apendicitis aguda by Ivette Wininter Ojeda Jazmín Wininter Ojeda, Norma Cecilia Villacreses Dueñas, Carmen Concepción Moncayo Valencia, Pamela Nicole Garcés Martínez, Andrea Stephanie León López, William Omar Fernández Concepción

“…Clínicamente cursa con dolor abdominal agudo en el cuadrante inferior derecho, fiebre y nauseas o vómitos, que, de no tratarse a tiempo, puede llevar a complicaciones graves como peritonitis y absceso del apéndice que pueden dar al traste con la vida del niño. …”
Get full text

Virtual screening assisted identification of a phytocompound as potent inhibitor against Candida lusitaniae; an in-silico study by Rimsha Timotheous, Habiba Naz, Usman Arif, Momna Toqeer Dar, Muhammad Farhan Sarwar, Mudassar Fareed Awan, Sajed Ali, Safia Obaidur Rab

“…Abstract Candida lusitaniae is one of the fungal species which causes serious health illnesses including peritonitis, vaginitis and fungemia, among others. Several antifungal drugs have been designed to tackle its infections but their efficacy is still questionable due to their associated side effects. …”
Get full text

Clinical report of Mediterranean fever in a child in Ukraine – Don’t miss it! by К.Y. Pashenko, Т.V. Frolova, Y.V. Кarpushenko, G.R. Muratov, О.М. Savvo, Т.О. Khalturina, О.М. Ashcheulov

“…Familial Mediterranean Fever (clinically). Peritonitis. Operative laparoscopic and conservative treatment was performed. …”
Get full text

Primary Prophylaxis to Prevent the Development of Hepatic Encephalopathy in Cirrhotic Patients with Acute Variceal Bleeding by Fátima Higuera-de-la-Tijera, Alfredo I. Servín-Caamaño, Francisco Salas-Gordillo, José L. Pérez-Hernández, Juan M. Abdo-Francis, Jaime Camacho-Aguilera, Sai N. Alla, Fiacro Jiménez-Ponce

“…Two patients (10%) treated with lactulose and a patient (4.5%) in the placebo group developed spontaneous bacterial peritonitis due to E. coli; one of them died due to recurrent variceal bleeding. …”
Get full text

The Antinociceptive and Anti-Inflammatory Activities of Aspidosperma tomentosum (Apocynaceae) by Anansa Bezerra de Aquino, Luiz Henrique Agra Cavalcante-Silva, Carolina Barbosa Brito da Matta, Willians Antônio do Nascimento Epifânio, Pedro Gregório Vieira Aquino, Antônio Euzébio Goulart Santana, Magna Suzana Alexandre-Moreira, João Xavier de Araújo-Júnior

“…In the thioglycolate-induced peritonitis, only EtAcO 100% fraction was not active. …”
Get full text

Indications for Endoscopic Ultrasound-Guided Pancreatic Drainage: For Benign or Malignant Cases? by Daisuke Uchida, Hironari Kato, Yosuke Saragai, Saimon Takada, Sho Mizukawa, Shinichiro Muro, Yutaka Akimoto, Takeshi Tomoda, Kazuyuki Matsumoto, Shigeru Horiguchi, Hiroyuki Okada

“…The adverse event (AE) rate was 26.7% (4/15) and included cases of peritonitis, bleeding, and stent migration. Reinterventions were performed in three patients with benign strictures and two with malignant strictures. …”
Get full text

Comparación de los resultados de la cirugía laparoscópica y la abierta en la reintervención de pacientes con complicaciones posoperatorias graves by Anival Ernesto Ramos Socarrás, Nersa Enid Peña Pupo, Ruber Luis Gallardo Arzuaga, Felipe Verdecia Acuña, Andrés José Quesada Vázquez

“…Resultados: Previo a la reintervención, la tensión arterial media fue similar en ambos grupos (experimental 91,3 mmHg; control 89,5 mmHg); el por ciento de casos con CA previa en el grupo experimental, 67,6 % y en este grupo predominó la fuga anastomótica (42,65 %) y la peritonitis posoperatoria (25 %). Después de la reintervención, en el grupo control resultó superior la infección del sitio quirúrgico (59,7 % vs. 16,2 %) y las fístulas intestinales externas (22,6 %). …”
Get full text

Evaluation of the Anti-Inflammatory and Antinociceptive Effects of the Essential Oil from Leaves of Xylopia laevigata in Experimental Models by João Carlos C. Queiroz, Ângelo R. Antoniolli, Lucindo J. Quintans-Júnior, Renan G. Brito, Rosana S. S. Barreto, Emmanoel V. Costa, Thanany B. da Silva, Ana Paula Nascimento Prata, Waldecy de Lucca, Jackson R. G. S. Almeida, Julianeli T. Lima, Jullyana S. S. Quintans

“…Acute administration of EOX exhibited a significant (P<0.01 or P<0.001) anti-inflammatory profile in the carrageenan-induced peritonitis and by the carrageenan-induced hindpaw edema tests in mice. …”
Get full text

Esophagoplasty Using a Jejunum Segment on a Vascular Pedicle by D. V. Ruchkin, V. A. Kozlov, M. M. Khamidov, D. E. Okonskaya, N. B. Kovalerova

“…Relaparotomy was required in one patient on day 7 after surgery for bile peritonitis, the cause of which was destructive acalculous cholecystitis with perforation. …”
Get full text

Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation by Bo Ye, Tianzhu Tao, Andong Zhao, Liyuan Wen, Xiaofei He, Yi Liu, Qiang Fu, Weidong Mi, Jingsheng Lou

“….-) injected with recombinant IL-17A, anti-IL-17A ab, anti-IL-17R ab, or isotype controls to evaluate the potential effects of IL-17A/IL-17R blockade in the prevention of SAE. Septic peritonitis induced significant impairment of learning memory and exploratory activity, which was associated with a higher expression of IL-17A, IL-1β, and TNF-α in the brain homogenate. …”
Get full text

Successful Use of Negative Pressure Wound Therapy for Abdominal Wall Necrosis Caused by a Perforated Ascending Colon Using the ABThera System by Kouki Imaoka, Takuya Yano, Yasuhiro Choda, Ko Oshita, Yuma Tani, Tetsushi Kubota, Michihiro Ishida, Daisuke Satoh, Masanori Yoshimitsu, Kanyu Nakano, Masao Harano, Hiroyoshi Matsukawa, Hitoshi Idani, Shigehiro Shiozaki, Masazumi Okajima

“…Based on a diagnosis of peritonitis resulting from a perforated ascending colon, emergency surgery was performed. …”
Get full text

Adoptive cell transfer of piezo-activated macrophage rescues immunosuppressed rodents from life-threating bacterial infections by Xiaoyi Liu, Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao, Shaohua Ge, Jianhua Li

“…Moreover, we test the use of these piezo-activated macrophages (piezoMϕ) as adoptive cell therapy (ACT) for treating various immunosuppressive bacterial infections, including sepsis, pneumonia and peritonitis. Our study thus highlights the potential application of catalytic nanoparticles as a promising alternative to conventional infection treatment to effectively modulate the innate immune responses and to engineer macrophages for immunotherapy purposes.…”
Get full text

Cytokines as Early Markers of Colorectal Anastomotic Leakage: A Systematic Review and Meta-Analysis by Cloë L. Sparreboom, Zhouqiao Wu, Adem Dereci, Geesien S. A. Boersema, Anand G. Menon, Jiafu Ji, Gert-Jan Kleinrensink, Johan F. Lange

“…This meta-analysis evaluates whether systemic or peritoneal inflammatory cytokines may contribute to early detection of CAL. …”
Get full text

Suture versus tacker closure of the peritoneum in transabdominal preperitoneal repair of inguinal hernia: A prospective comparative cohort study by C. Rajagopal, M. Sunil Krishna, Pavan M. Bhat

“…A total of 80 patients were included in the study, of which 50 underwent peritoneal closure by tackers and 30 underwent peritoneal closure by sutures based on the standard of care of the operating surgeon. …”
Get full text

MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy by Jiabin Liang, Jingxiu Zhao, Lin Yang, Qian Wang, Jing Liao, Jianhao Li, Weizhao Zhuang, Fanghong Li, Jinxian He, Yukuan Tang, Hanwei Chen, Chen Huang

“…Abstract Background Peritoneal fibrosis (PF) is a serious complication commonly associated with prolonged peritoneal dialysis. …”
Get full text

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature by Shan-shan Su, Guo-qi Zheng, Ya-gang Liu, Yue-feng Chen, Zhao-wei Song, Shu-jing Yu, Ning-ning Sun, Yu-xin Yang

“…Malignant peritoneal mesothelioma with invasion of the liver is an invariably fatal disease. …”
Get full text