Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus by Qian Ge, Xin Xin Xie, Xiaoqiu Xiao, Xi Li

“…Pathologic conditions associated with type 2 diabetes (such as high blood glucose, inflammation, hypoxia, and fatty acids) can alter the quantity and components of ELVs secreted from the pancreas or peripheral insulin-targeting tissues. These released ELVs can either enter the blood circulation or be taken up by neighboring cells or macrophages, which can lead to insulin resistance or β-cell apoptosis. …”
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Acquired Myelodysplasia or Myelodysplastic Syndrome: Clearing the Fog by Ethan A. Natelson, David Pyatt

“…Myelodysplastic syndromes (MDS) are clonal myeloid disorders characterized by progressive peripheral blood cytopenias associated with ineffective myelopoiesis. …”
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CXCR2 Is Essential for Radiation-Induced Intestinal Injury by Initiating Neutrophil Infiltration by Jing Hu, Qian Ji, Fei Chen, Xiaoqin Gong, Chuansheng Chen, Kaijun Zhang, Ye Hua, Jinlei Wang, Rongkun Li, Xu Wang, Chunhua Dai, Ye Tian

“…Neutrophils, known as an important part of the immune system, are the most abundant leukocyte population in peripheral blood, but excessive recruitment will lead to tissue/organ injury. …”
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Novel Vascular Malformation in an Affected Newborn with Deletion Del(4)(q31.3) by Norma Elena de León Ojeda, Michel Soriano-Torres, Mercedes J. Cabrera, Dunia Bárbara Benítez Ramos

“…The patient died due to multiple congenital malformations; a peripheral chromosome analysis showed 46, XY, del(4)(q31.3) de novo. …”
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Calcified Leiomyoma of the Distal Forearm in a Child: A Case Report and Review of Literature by Nadeeke Nidhan Perera, Sunil Ranjith Wijayasinghe, Karuna Dissanayake, Jerard Fernando, Ethige Tharushi De Silva

“…A diagnosis of a cartilage-forming lesion or a peripheral nerve sheath tumour was suggested. The lesion was completely excised. …”
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I giovani maoresi e la mobilità. La sfida dell’istruzione tra vecchie e nuove disuguaglianze by Paola Schierano

“…By interweaving ethnographic experience and in-depth historical analysis, this article offers a contribution to a wider reflection on youth and inequalities, looking at the gap between centres and (ultra)peripheral regions. It analyses the educational system of Mayotte, characterized by the integration of republican school and Koranic school, as well as factors and limitations to Mahoran students’ mobility. …”
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Basal Cell Ameloblastoma of Mandible: A Rare Case Report with Review by Hemant Shakya, Vikram Khare, Nilesh Pardhe, Ena Mathur, Mansi Chouhan

“…Basal cell ameloblastoma is believed to be the rarest histologic subtype in which the tumor is composed of more primitive cells and has even fewer features of peripheral palisading. Till date, only few cases of basal cell ameloblastoma have been reported in the literature. …”
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Stem Cells in the Treatment of Neuropathic Pain: Research Progress of Mechanism by Meichen Liu, Kai Li, Yunyun Wang, Guoqing Zhao, Jinlan Jiang

“…We found that the multiple-mechanism approach was different from the single mechanism of routine clinical drugs; stem cells play a role in peripheral mechanism, central mechanism, and disinhibition of spinal cord level that lead to neuropathic pain, so they are more effective in analgesia and treatment of neuropathic pain.…”
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Autoimmune Hemolytic Anemia and Immune Thrombocytopenia: A Unique Presentation of Kawasaki Disease by Chloe Kupelian, Bindu Sathi, Deepika Singh

“…The presentation is typically preceded by five or more days of fever with additional clinical findings including rash, peripheral edema, mucositis, conjunctival changes, and unilateral cervical lymphadenopathy. …”
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Endothelial-Leukocyte Interaction in Severe Malaria: Beyond the Brain by Mariana C. Souza, Tatiana A. Padua, Maria G. Henriques

“…Severe malaria is a systemic illness characterized by dysfunction of brain tissue and of one or more peripheral organs as lungs and kidney. The most severe and most studied form of malaria is associated with cerebral complications due to capillary congestion and the adhesion of infected erythrocytes, platelets, and leukocytes to brain vasculature. …”
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Wilson’s Disease and Autoimmune Hepatitis Coexistence: A Cause of Diagnostic Delay by Mohammed G Mudawi, Salma Barakat MD, Elhadi M Awooda

“…The physical assessment showed moderate ascites and small liver size, and no other peripheral evidence of chronic liver disease was observed. …”
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The determination of effects of in ovo administrated bisphenol a on the development of thymus and proportion of alpha-naphthyl acetate esterase enzyme lymphocyte by using histologi... by Didem Yılmaz, Yasemin Öznurlu

“…At the same time, in BPA-treated groups, lymphoid tissue had less cell density and the number of ANAE positive lymphocytes decreased. The percentage of peripheral blood ANAE positive lymphocytes was significantly lower in the BPA-treated groups than in the control groups (p <0.05).…”
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Anterior and posterior tibial anesthetic block in diabetic foot surgery. by José Julio Ojeda González, Evangelina Dávila Cabo, Remberto González Enoa, Obdulio Rodríguez García

“…Its morbidity is derived from its own complications which are produced at a long or short term and peripheral vascular disease hihglights among them.<strong>Objective</strong>: to check the usefulness of the anterior and posterior blockade of the tibia for the surgery of the diabetic foot.…”
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Immunomodulatory effects of inosine pranobex on cytokine production by human lymphocytes by Lasek Witold, Janyst Michał, Wolny Rafał, Zapała Łukasz, Bocian Katarzyna, Drela Nadzieja

“…In the present study, effects of Inos on the production of cytokines attributable to Th1 (IL-2, IFN-g, and TNF-a) or Th2 cells (IL-4, IL-5, and IL-10) were tested in human peripheral blood lymphocyte cultures stimulated with phytohemagglutinin (PHA). …”
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Algebraic and topological indices of molecular pathway networks in human cancers by Peter Hinow, Edward A. Rietman, Sara Ibrahim Omar, Jack A. Tuszyński

“…Interestingly, these sources of symmetry are often central rather than peripheral. Our results can aide in identification of promising targets for anti-cancer drugs. …”
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P-ANCA Systemic Vasculitis Induced by Brucellosis in an Elderly Male Patient by Mohammed Cheikh, Abdulrahman Kabli, Esraa Sendi, Hani Almoallim

“…All symptoms improved from the third month of follow-up except weakness from peripheral neuropathy with normalization of P-ANCA titer. …”
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Surgical Excision with Forehead Flap as Single Modality Treatment for Basal Cell Cancer of Central Face: Single Institutional Experience of 50 Cases by Jagdeep Rao, Harsh Deora

“…The WHO has defined it as “a locally invasive, slowly spreading tumor which rarely metastasizes, arising in the epidermis or hair follicles and in which the peripheral cells usually simulate the basal cells of the epidermis.” …”
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Microangiopathic Hemolytic Anemia: A Rare Complication of Acute Pancreatitis by Syedda Ayesha, Masood Muhammad Karim, Maria Ali, Abdul Hadi Shahid, Salman Naseem Adil

“…Clinicians should maintain a high index of suspicion in patients with acute pancreatitis who present with anemia, thrombocytopenia, and schistocytes on peripheral smears, even in the absence of end-organ injuries and with normal ADAMTS13 activity. …”
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Vulvar Malignancy in Neurofibromatosis Syndrome by Angela Musella, Innocenza Palaia, Lavinia Domenici, Assunta Casorelli, Angela Martoccia, Pierluigi Benedetti Panici

“…Type 1 neurofibromatosis (NF1) is a dominantly inherited neurologic disorder that affects primarily the skin, bones, and peripheral nervous system. It may be associated with a variety of clinical manifestations including cafe-au-lait spots, skinfold freckling, Lisch nodules, and visceral neurofibromas. …”
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Protocol for a patient-derived preclinical platform to model tumor-immune interactions and evaluate therapeutic efficacy by Wen-Hsin Chang, Andrew I. Chin, Ching-Hsien Chen

“…We outline steps for isolating human peripheral blood mononuclear cells (PBMCs), preparing patient-derived precision-cut tumor slices (PCTSs), cryopreserving the samples, and setting up the co-culture system. …”
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