Enhancing Exercise Responsiveness across Prediabetes Phenotypes by Targeting Insulin Sensitivity with Nutrition by Julian M. Gaitan, Arthur Weltman, Steven K. Malin

“…Caloric restriction is an approach to enhance the effect of exercise on increasing peripheral and hepatic insulin sensitivity, as replenishing expended calories blunts these benefits. …”
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Influence of Urban Development on Extreme Precipitation in Plateau Lake Basin by LI Baofen, LI Xiaopeng, CAO Yimei, JIN Zhuo

“…Studying the influence of urban development on extreme precipitation in the lake basin region is of practical significance for urban flood control and disaster reduction,forecasting and early warning capability increase and emergency response capacity building,“four pres” improvement,and risk tackling of extreme precipitation and waterlogging disasters.Taking Kunming,a city in the Yunnan Plateau Basin,as an example,this paper adopts mathematical statistical methods to analyze the effect of urban development on the extreme precipitation index in the central urban area of the lake basin,the basin edges,and peripheral hilly areas of the city.The results show that urban development exerts different degrees of influence on various extreme precipitation indexes in lake basin areas,basin edges,and peripheral hilly areas of the basin, with the strongest,weakest,and middle effects on the basin edges, hilly areas,and lake basin areas respectively.Due to topography and the urban heat island effect,urban development also causes uneven increase and decrease in the extreme precipitation index in various areas such as lake basin areas,basin edges,and hilly areas.…”
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Dévaluation interne, politiques structurelles et réductions des déficits publics : les réponses apportées par la « troïka » sont-elles un remède aux déséquilibres externes des pays... by Francisco Serranito

“…We show that the implementation of these structural adjustment programs in the euro area peripheral countries comes from an erroneous interpretation of the origins of the crisis of sovereign debt. …”
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Evaluation of the integrated Traditional Chinese and Western medicine nursing for high-risk patients with diabetic foot (高危糖尿病足患者的中西医结合护理干预效果观察)... by ZHI Hui (智慧), LIU Jinjing (刘津京), GUO Jing (郭晶), WANG Xiaodi (王晓娣), TONG Fenfei (仝粉飞), ZHENG Wen (郑雯), E Haiyan (鄂海燕), TANG Ling (唐玲)

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Candidate SNP markers of changes in the expression levels of the human <i>SCN9A</i> gene as a hub gene for pain generation, perception, response and anesthesia by P. A. Dotsenko, K. A. Zolotareva, R. A. Ivanov, I. V. Chadaeva, N. L. Podkolodnyy, V. A. Ivanisenko, P. S. Demenkov, S. A. Lashin, M. P. Ponomarenko

“…On the evolutionary scale by the Kyoto Encyclopedia of Genes and Genomes (KEGG), the ancestor is the phylum Chordata, some of the most ancient of which evolved the central and the peripheral nervous system. Next, with our tool called ANDSystem, we found that phosphorylation of ion channels is a centerpiece in pain generation, perception, response and anesthesia, on which the efficiency of signal transduction from the peripheral to the central system depends. …”
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Acute therapeutic effects and pathophysiology of eosinophilic granulomatosis with polyangiitis neuropathy by Fumitaka Shimizu, Mariko Oishi, Toshihiko Maeda, Yukio Takeshita, Hideaki Nishihara, Ryota Sato, Takashi Kanda, Masayuki Nakamori, Michiaki Koga, Miwako Fujisawa, Yuki Mizumoto, Nanami Yamanaka, Takashi Nawata, Tatsuya Okafuji, Susumu Fujikawa, Kinya Matsuo, Joe Nemoto, Masaya Honda

“…Objective This study investigated the effects of early treatment and pathophysiology on eosinophilic granulomatosis with polyangiitis neuropathy (EGPA-N).Methods Twenty-six consecutive patients with EGPA-N were diagnosed and treated within a day of admission and underwent clinical analysis. Peripheral nerve recovery rates were evaluated after early treatment by identifying the damaged peripheral nerve through detailed neurological findings.Results The eosinophil count at onset was significantly correlated with the total number of damaged nerves. …”
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Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome by Kishan Kumar Nyati, Kashi Nath Prasad

“…Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system, mostly triggered by an aberrant immune response to an infectious pathogen. …”
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Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder? by Jay P. Patel, Benicio N. Frey

“…The blood-brain barrier (BBB) regulates the transport of micro- and macromolecules between the peripheral blood and the central nervous system (CNS) in order to maintain optimal levels of essential nutrients and neurotransmitters in the brain. …”
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Citrus/Cydonia Comp. Can Restore the Immunological Balance in Seasonal Allergic Rhinitis-Related Immunological Parameters In Vitro by E. W. Baars, H. F. J. Savelkoul

“…In two in vitro studies, we examined the immunological (pathways of the) effects of Citrus/Cydonia comp. from, respectively, a healthy and an allergic donor; peripheral blood mononuclear cells (PBMCs) were isolated out of peripheral blood and analyzed in vitro after polyclonal stimulation of T-cells. …”
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Small fiber pathology in fibromyalgia syndrome by Claudia Sommer, Nurcan Üçeyler

“…The question whether peripheral or central nervous system changes come first, or whether both are signs of an underlying pathology, has not been resolved yet. …”
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Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report by Olivia Ling-I Tseng, John Thomas Kelsall, Pearce George Wilcox

“…Eosinophilia was noted in peripheral blood and, subsequently, on bronchoalveolar lavage. …”
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Iatrogenic Femoral Arteriovenous Fistula with Pseudoaneurysm Associated with Worsening Heart Failure Years after Percutaneous Impella Placement by Andy Y. Wang, Ali Al Jabri, Edward R. Jewell, Angela L. Jellison

“…This case study highlights a rare access-site complication from percutaneous Impella placement associated with worsening heart failure, strategies for preventing this complication during peripheral access, and the need to consider this differential in such a patient with a history of peripheral access who has an unexplained worsening of heart failure.…”
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The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia by Alexandra Pérez Pérez, Rahul Lazarus, Anju Dubey

“…COVID-19 has various imaging manifestations, most commonly peripheral ground-glass opacities with a basilar posterior predominance. …”
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Methaemoglobinemia Induced by MDMA? by L. L. W. Verhaert

“…Physical examination showed cyanosis with a peripheral saturation (SpO2) of 85%, he did not respond to supplemental oxygen. …”
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Le street art à Naples by Christine Salomone

“…Yet spontaneous or non-spontaneous initiatives in favour of urban art from various neighbourhoods – at the margins of the historic centre or more peripheral neighbourhoods - have grown and become denser. …”
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Eales’ Disease: When the Rare Sounds Frequent by Beatriz Oliveira Lopes, Margarida Sena Brízido, Ana Isabel Reis, Margarida Maria Miranda, Susana Morais Pina

“…Eales’ disease is a peripheral occlusive retinal phlebitis, with an unclear pathogenesis. …”
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The Role of Purinergic Receptors in Cancer-Induced Bone Pain by Sarah Falk, Maria Uldall, Anne-Marie Heegaard

“…In nociception, ATP acts as an extracellular messenger to transmit sensory information both at the peripheral site of tissue damage and in the spinal cord. …”
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Acute Eosinophilic Ascites in a Middle-Aged Man by Fadi Bleibel, Keith Fragoza, Garrey T. Faller

“…Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, thickening of the stomach and small bowel wall, and elevated serum IgE. …”
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Massive Scrotal Edema: An Unusual Manifestation of Obstructive Sleep Apnea and Obesity-Hypoventilation Syndrome by Stephanie E. Dreifuss, Ernest K. Manders

“…Furthermore, if OSA is recognized as the cause of right heart failure, and if the apnea is corrected, the resultant improvement in cardiac function may allow reversal of massive peripheral, including scrotal, edema.…”
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Predicting corneal decompensation in Fuchs endothelial corneal dystrophy with Scheimpflug tomography and clinical parameters by Nilufer Yesilirmak, Vaël Souédan, Aurélie Pison, Jean Louis Bourges

“…In addition, we extracted topographic measurements including central corneal thickness (CCT); corneal volumes (CVs) within 3, 5, and 7 mm diameters (CV3, CV5, CV7); corneal central-to-peripheral volume ratios (CPVRs) for 3/5 mm (CPVR-3/5) and 3/7 mm (CPVR-3/7); peripheral volume index; thinnest point; corneal thickness spatial profile at 2, 4, 6, and 8 mm (CTSP2, CTSP4, CTSP6, CTSP8); corneal central-to-peripheral thickness ratio at 4 mm (CPTR4); and percentage of thickness increase at 2, 4, and 6 mm (PTI2, PTI4, PTI6), loss of regular isopachs (LRI), displacement of the thinnest point (DTP), and focal posterior surface depression (FPSD). …”
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