All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study by Deng Li, Peng Wang, Yuxi Li, Zhongyu Xie, Le Wang, Hongjun Su, Wen Deng, Yanfeng Wu, Huiyong Shen

“…Bone marrow-derived MSCs from healthy donors were pretreated with ATRA and cocultured with CD3/28-activated peripheral blood mononuclear cells (PBMCs) derived from AS patients. …”
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Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa by Tandi E. Matsha, Carmen Pheiffer, Stephen E. Humphries, Junaid Gamieldien, Rajiv T. Erasmus, Andre P. Kengne

“…To conduct a genome-wide DNA methylation in individuals with type 2 diabetes, individuals with prediabetes, and control mixed ancestry individuals from South Africa. Methods. We used peripheral blood to perform genome-wide DNA methylation analysis in 3 individuals with screen detected diabetes, 3 individuals with prediabetes, and 3 individuals with normoglycaemia from the Bellville South Community, Cape Town, South Africa, who were age-, gender-, body mass index-, and duration of residency-matched. …”
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Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis by Ying Zhang, Rong Cao, Haijian Ying, Juping Du, Shuaishuai Chen, Na Wang, Bo Shen

“…TLR10 levels in B cells and B cell subsets (CD19+CD27+, CD19+CD27−, CD27+IgD−, CD27+IgD+, CD27−IgD+, D27−IgD−, CD19+CD5+, and CD19+CD5−) and inflammatory biomarker concentrations in peripheral blood (PB) obtained from RA subjects and HCs were detected by flow cytometry and enzyme-linked immunosorbent assay (ELISA), respectively. …”
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Acute Abdomen as a Clinical Presentation of COVID-19-Associated Multisystem Inflammatory Syndrome in Children by Elmira Hajiesmaeil Memar, Fatemeh Tahghighi, Sedigheh Yousefzadegan, Parisa Sadeghirad, Ashraf Mousavi, Ramin Zare Mahmoudabadi, Hossein Saeidi, Mehri Ayati, Sahar Naderi, Sara Memarian, Seyedmusa Zeinalabedin, Bahar Ashjaei, Hojatollah Raji, Leila Tahernia, Hosein Alimadadi, Vahid Ziaee

“…Patients experiencing unexplained acute abdominal pain along with fever, skin rash, and peripheral edema, who had a history of COVID-19 infection prior to or during the episode of acute abdomen symptoms, should be considered to have MIS-C. …”
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Sex-based variations in breath-holding: oxygen storage and diving response among non-divers by Frank Pernett, Erika Schagatay, Erika Schagatay, Pontus Holmström, Pontus Holmström

“…We conducted a study comparing the maximum breath-hold duration, heart rate (HR) reduction, peripheral oxygen saturation (SpO2), and spleen volume and contraction in 37 men and 44 women, all of whom had no prior breath-holding experience. …”
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Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not so... by Sofia Lyng Wæver, Kristian Agmund Haanes

“…IHC following injections with monoclonal CGRP antibodies in KO mice ruled out the possibility that the βCGRP observed in trigeminal neurons had peripheral origins. This conclusion was enhanced by IHC experiments which showed the presence of CGRP co-localizing sorting peptides in KO mice. …”
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Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis by Hongliang Zhang, Tingting Chen, Yunyan Zhang, Jiangbo Lin, Wenjun Zhao, Yangyang Shi, Huichong Lau, Yang Zhang, Minjun Yang, Cheng Xu, Lijiang Tang, Baohui Xu, Jianjun Jiang, Xiaofeng Chen

“…The gene expression in peripheral mononuclear cells was profiled through next-generation RNA sequencing. …”
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Different immunological characteristics of asymptomatic and symptomatic COVID-19 patients without vaccination in the acute and convalescence stages by Li Li, Xin Zhang, Huimin Yan, Muwei Dai, Huixia Gao, Yuling Wang, Ping Jiang, Erhei Dai

“…In this study, we performed high-throughput single-cell mass cytometry on peripheral blood samples from 10 COVID-19 patients and four healthy donors to analyze their immune status at acute and convalescence phases. …”
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EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study by John Reynolds, Katie Hesketh, Matthew Cocks, Megan Quickfall, Alex J Wadley, Scott Green, Jet Veldhuijzen Van Zanten

“…Measures of feasibility and acceptability will be reported, and peripheral blood will be collected at weeks 0, 12 and 18 to explore whether the frequency, phenotype and metabolic profile of lymphocyte subsets has changed. …”
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Wild pea (<i>Pisum sativum</i>Pisum sativum L. subsp. <i>elatius</i> (Bieb.) Aschers. et Graebn. s.l.) at the periphery of its range: Zagros Mountains by O. E. Kosterin, V. S. Bogdanova, A. V. Mglinets

“…However, wild pea diversity in peripheral regions is insufficiently represented in the existing germplasm collections. …”
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Coexistence of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Sjogren Syndrome, Antiphospholipid Syndrome, and Ankylosing Spondylitis by Moshiur Rahman Khasru, Md Abu Bakar Siddiq, Kazi Mohammad Sayeeduzzaman, Tangila Marzen, Abul Khair Mohammad Salek

“…Clinical examination unveiled asymmetrical peripheral and both sacroiliac joint tenderness, positive modified Schober’s test, and limited chest expansion. …”
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Physical Activity and Quality of Life in Retinitis Pigmentosa by Joshua D. Levinson, Ethan Joseph, Laura A. Ward, Joe R. Nocera, Machelle T. Pardue, Beau B. Bruce, Jiong Yan

“…VFQ-25 revealed statistically significant differences between the active and insufficiently active patients, including overall visual function (53.3 versus 45.1, p=0.010), color vision (73.8 versus 52.9, p<0.001), and peripheral vision (34.3 versus 23.8, p=0.021). The physical component of the SF-36 and the PAT-D survey also demonstrated statistically significant differences (47.2 versus 52.9, p=0.002; 24.3 versus 30.0, p=0.010). …”
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IgG4-Related Autoimmune Prostatitis: Is It an Unusual or Underdiagnosed Manifestation of IgG4-Related Disease? by María T. Bourlon, Mónica Sánchez-Ávila, Fredy Chablé-Montero, Ricardo Arceo-Olaiz

“…Involved prostate zones include mainly central and transitional zones and less frequently the peripheral. Currently, there is insufficient data about the natural history and outcome. …”
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The safety and efficacy of neutral electrolyzed water solution for wound irrigation: post-market clinical follow-up study by Veronika Valdová, Vladimíra Štěpánová, Lenka Lapčíková

“…The most common comorbidities and risk factors were obesity, diabetes mellitus, and peripheral artery disease. Significant improvement was observed in all parameters, including pain, malodor, affected tissues, reduction in wound size, and granulation and epithelization. …”
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Biological effectiveness of combined exposure to neutrons and gamma radiation applied in two orders of sequence: Relevance for biological dosimetry after nuclear emergencies by Tomas Palmqvist, Milagrosa Lopez-Riego, Martin Bucher, Ursula Oestreicher, Stefan Pojtinger, Ulrich Giesen, Iuliana Toma-Dasu, Andrzej Wojcik

“…Objective: To investigate the potential impact of two different combinations of neutron and gamma radiation on gene expression and dicentric chromosomes in peripheral blood mononuclear cells (PBMC). Methods: Whole blood from 3 human donors was exposed to neutrons with an energy spectrum similar to that of the Hiroshima uranium bomb, to gamma radiation from a 60Co source and to a 50:50 combination of both radiations, given in two orders of sequence. …”
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Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation by Nivedita U. Jerath, Cameron D. Crockett, Steven A. Moore, Michael E. Shy, Conrad C. Weihl, Tsui-Fen Chou, Tiffany Grider, Michael A. Gonzalez, Stephan Zuchner, Andrea Swenson

“…Our patient reflects the clinical heterogeneity of VCP mutations, as his neurological localization is a spectrum between a lower motor neuron disorder and a hereditary axonal peripheral neuropathy such as CMT2. Our case demonstrates a rare manifestation of the c.290 C>T, pGly97Glu VCP mutation.…”
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Case report of neurobrucellosis: a rare complication and neuroimaging findings of a common disease by Yu Zhang, Yu Zhang, Xiao-Yi Zou, Xiao-Yi Zou, Ling Liu

“…This study was approved by and conducted in accordance with the recommendations of West China Hospital’s ethics -.1clinical manifestations of neurobrucellosis in these patients included meningitis, meningoencephalitis, encephalitis, cranial neuropathy, intracranial hypertension, radiculitis, peripheral neuropathy, myelitis, and other psychiatric symptoms. …”
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Plasmodium falciparum Merozoite Surface Proteins Polymorphisms and Treatment Outcomes among Patients with Uncomplicated Malaria in Mwanza, Tanzania by Karol J. Marwa, Eric Lyimo, Eveline T. Konje, Anthony Kapesa, Erasmus Kamugisha, Göte Swedberg

“…The influence of MOI on peripheral parasite clearance and adequate clinical and parasitological response (ACPR) was also assessed. …”
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Supplementation with Korean Red Ginseng Improves Current Perception Threshold in Korean Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo-Controlled Trial by Kahui Park, YuSik Kim, Junghye Kim, Shinae Kang, Jong Suk Park, Chul Woo Ahn, Ji Sun Nam

“…In this study, we investigated the effects of KRG administration on diabetic peripheral neuropathy in T2DM patients. Methods. This study was a randomized, double-blind, placebo-controlled trial. …”
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Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease by Fu-An Chen, Chih-Yu Yang, Wu-Chang Yang, Jinn-Yang Chen, Yee-Yung Ng, Szu-Yuan Li, Wen-Sheng Liu, Shiao-Ti Cheng, Yu-Jen Wang, Chih-Ching Lin

“…Ankle-brachial index (ABI) is an accurate tool to diagnose peripheral arterial disease. The aim of this study was to evaluate whether ABI is also a good predictor of renal outcome and cardiovascular events in patients with chronic kidney disease (CKD). …”
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