SALIVARY FUNCTION AND BIOMARKER PROFILES IN RELATION TO ORAL HEALTH IN PATIENTS WITH PRE-DIALYSIS CHRONIC KIDNEY DISEASE by Georgiana Florentina Gheorghe, Laura Iosif, Oana Elena Amza, Bogdan Dimitriu, Liliana Gârneaţâ, Alexandra Ripszky Totan, Ana Maria Cristina Ţâncu

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Qualitative analysis of cardiovascular disease prevention in dental practice by Áine O'Farrell, Chee H. Liew, Rosemary Geoghegan, Gerard T. Flaherty

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The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research by Zihui Liu, Qing Cao, Wenqing Wang, Bowen Wang, Yilun Yang, Cory J. Xian, Tiejun Li, Yuankun Zhai

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Deep Learning Architecture to Infer Kennedy Classification of Partially Edentulous Arches Using Object Detection Techniques and Piecewise Annotations by Zohaib Khurshid, MRes, FDTFEd, FHEA, Maria Waqas, PhD, Shehzad Hasan, PhD, Shakeel Kazmi, PhD, Muhammad Faheemuddin, FCPS

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SOME ASPECTS OF TEETH ERUPTION. A LITERATURE REVIEW by L.V. Smaglyuk, Н.V. Voronkova, A.Y. Karasiunok

Subjects: “…gingival smile, the altered passive eruption of frontal teeth, the altered active eruption of frontal teeth, diagnosis of the altered eruption of teeth, condition of periodontal tissues during orthodontic treatment.…”
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Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…Periodontitis is an inflammatory disease caused by pathogenic microorganisms and characterized by the destruction of the periodontium. …”
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The Possible Role of Neutrophils in the Induction of Osteoclastogenesis by Carolyn G. J. Moonen, Teun J. de Vries, Patrick Rijkschroeff, Patrice E. Poubelle, Elena A. Nicu, Bruno G. Loos

“…The ligand of the receptor activator of NF-κB (RANKL) is a key molecule in the formation of osteoclasts, the key cells that cause the disease-associated alveolar bone resorption in periodontitis. We hypothesized that polymorphonuclear leukocytes (PMNs), found as the most prominent cells of inflamed periodontal tissues, could play an important role in providing signals to trigger osteoclastogenesis and thus activating pathological bone resorption in periodontitis. …”
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Antimicrobial Effect of Platelet-Rich Plasma against Porphyromonas gingivalis by Thuy Anh Vu Pham, Thao Thi Phuong Tran, Ngan Thi My Luong

“…This material can become an adjunct to periodontal treatment.…”
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Minimally Invasive Periodontology: A Treatment Philosophy and Suggested Approach by Ethan Ng, John Rong Hao Tay, Marianne Meng Ann Ong

“…Severe periodontitis is a highly prevalent dental disease. With the advent of implant dentistry, teeth are often extracted and replaced. …”
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Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. by Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Bartlomiej Salamaga, Justyna Folkert, Krzysztof Rakus, Magdalena Chadzinska, Jan Potempa, Graham P Stafford, Tomasz K Prajsnar, Craig Murdoch

“…During periodontitis pathobionts such as Pg can enter the bloodstream and growing evidence correlates periodontitis with increased risk of cardiovascular and neurodegenerative diseases. …”
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Predictors for Gingival Index in Middle-Aged Asian Indians with Type 2 Diabetes from South India: A Cross-Sectional Observational Study by S. Jai Karthik, Shajith Anoop, R. Suresh Kumar, M. V. Usha Rani

“…T2DM patients (n=232, mean age: 50.6±10.4 years) with periodontitis (n=123, mean age: 54.3±2.4 years) and without periodontitis (n=109, mean age: 55.2±3.1 years) were recruited between 2014 and 2016 by purposive sampling method. …”
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Leptomeningeal Cells Transduce Peripheral Macrophages Inflammatory Signal to Microglia in Reponse to Porphyromonas gingivalis LPS by Yicong Liu, Zhou Wu, Xinwen Zhang, Junjun Ni, Weixian Yu, Yanmin Zhou, Hiroshi Nakanishi

“…Together with the inhibitory effect on microglial activation, propolis may be beneficial in preventing neuroinflammation during chronic periodontitis.…”
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Differential gene expression profile in Porphyromonas gingivalis treated human gingival keratinocytes and their role in the development of HNSCC by Dakshinya M, Anitha P, A.S. Smiline Girija, Paramasivam A, Vijayashree Priyadharsini J

“…Background: Periodontitis is considered to be one of the major risk factors associated with cancers of the oral cavity. …”
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M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p by Shan Chen, Jian Liu, Lilei Zhu

“…Macrophages play a pivotal role in regulating inflammatory response in periodontitis, a condition characterized by excessive osteoclast differentiation. …”
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Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers in Young Patients by Sophie Ronceray, Juliette Miquel, Antoine Lucas, Gérald E. Piérard, Trinh Hermanns-Lê, Anne De Paepe, Alain Dupuy

“…Ehlers-Danlos syndrome type VIII (EDS-VIII) is a very rare autosomal dominant disease characterized by early-onset periodontitis associated with features of Ehlers-Danlos syndrome. …”
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Correlation of Serum and Gingival Crevicular Fluid Levels of Caspase-3 and Milk Fat Globule–Epidermal Growth Factor 8 on Gingival Health by Manonmani Pavithra Ravindran, A Geetha, Sathish Rajendran, Jaideep Mahendra, M Jyothi, Ambalavanan Namasivayam

“…Spearman’s correlation showed a strong positive correlation between the serum and GCF levels of caspase-3 and periodontal parameters, whereas serum and GCF levels of MFG-E8 showed a strong negative correlation with the periodontal parameters. …”
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Evaluating the Preventive and Therapeutic Roles of Active Irrigation Systems in Root Canal Treatment: A Narrative Review and Critical Appraisal of Theory and Methodology by Ignacio Barbero-Navarro, Iuliana Sofian-Pauliuc, Maria Esther Irigoyen-Camacho, Marco Antonio Zepeda-Zepeda, David Ribas-Perez, Antonio Luis Castaño-Seiquer

“…Endodontic therapy aims at preventing or curing apical periodontitis. To conduct this, the cleaning and shaping of the canals are essential. …”
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Comparison of Oral Microbe Quantities from Tongue Samples and Subgingival Pockets by André Göhler, Stefanie Samietz, Carsten Oliver Schmidt, Thomas Kocher, Ivo Steinmetz, Birte Holtfreter

“…To improve understanding of periodontitis pathology, we need more profound knowledge of relative abundances of single prokaryotic species and colonization dynamics between habitats. …”
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IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture by Moore TC, Pinkerton TS, Petro TM

“…Restoration of IRF3 expression in IRF3KO RAW cells increased IL-6, restored NO, and decreased CCL22 production in response to LPS of E. coli.Discussion: Therefore, IRF3 is critical to the expression of pro- and anti-inflammatory factors produced by macrophages responding to LPS and could be a target during periodontitis treatment.Keywords: IRF3, lipopolysaccharide, macrophages, RAW264.7 cells, cytokines…”
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Porphyromonas gingivalis: Major Periodontopathic Pathogen Overview by Jaroslav Mysak, Stepan Podzimek, Pavla Sommerova, Yelena Lyuya-Mi, Jirina Bartova, Tatjana Janatova, Jarmila Prochazkova, Jana Duskova

“…Porphyromonas gingivalis is a Gram-negative oral anaerobe that is involved in the pathogenesis of periodontitis and is a member of more than 500 bacterial species that live in the oral cavity. …”
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