Maternal Diet Supplementation with n-6/n-3 Essential Fatty Acids in a 1.2 : 1.0 Ratio Attenuates Metabolic Dysfunction in MSG-Induced Obese Mice by Josiane Morais Martin, Rosiane Aparecida Miranda, Luiz Felipe Barella, Kesia Palma-Rigo, Vander Silva Alves, Gabriel Sergio Fabricio, Audrei Pavanello, Claudinéia Conationi da Silva Franco, Tatiane Aparecida Ribeiro, Jesuí Vergílio Visentainer, Elton Guntendeorfer Banafé, Clayton Antunes Martin, Paulo Cezar de Freitas Mathias, Júlio Cezar de Oliveira

“…We aimed to study whether a diet supplemented with a mixture of n-6/n-3 PUFAs, during perinatal life, attenuates outcomes of long-term metabolic dysfunction in prediabetic and obese mice. …”
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Antenatal pelvic floor muscle exercise intervention led by midwives in England to reduce postnatal urinary incontinence: APPEAL feasibility and pilot randomised controlled cluster... by Karla Hemming, Jonathan Bishop, Sarah Dean, Jean Hay-Smith, Tim Coleman, Elizabeth Edwards, Christine MacArthur, Debra Bick, Mark Pearson, Rohini Terry, Eivor Oborn, Sara Webb, Eleni Gkini, Victoria Salmon, Ellie Jones, Helena Frawley

“…Recent changes to the National Health Service perinatal pelvic healthcare means a full trial is not possible.Trial registration number ISRCTN10833250.…”
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Gut microbiota interacting with vitamin D but not anandamide might contribute to the pathogenesis of preeclampsia: a preliminary study by Xiao-Qiang Han, Xiao-Qiang Han, Hui-Hui Jiang, Meng-Ling Chen, Meng-Ling Chen, De-Yang Han, De-Yang Han, Su-Fen Zhou, Su-Fen Zhou, Jin-Wen Wang, Shu-Shen Ji, Ling-Yun Wang, Jing-Wei Lou, Ming-Qun Li, Ming-Qun Li

“…IntroductionPreeclampsia (PE) is a pregnancy-specific multisystem disorder and a leading cause of maternal and perinatal mortality globally. Despite numerous studies highlighting the potential roles of gut microbiota, anandamide (AEA), and Vitamin D (VitD) in PE, none have established them as reliable biomarkers for predicting disease onset. …”
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Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter by Vadim Dolgin, Pauline Chabosseau, Jacob Bistritzer, Iris Noyman, Orna Staretz‐Chacham, Ohad Wormser, Noam Hadar, Marina Eskin‐Schwartz, Bibi Kanengisser‐Pines, Ginat Narkis, Ramy Abramsky, Eilon Shany, Guy A. Rutter, Kyla Marks, Ohad S. Birk

“…Notably, previous studies demonstrated osteopenia and male‐specific cardiac death in mice lacking the ZnT5/SLC30A5 zinc transporter, and suggested association of two homozygous frameshift SLC30A5 variants with perinatal mortality in humans, due to hydrops fetalis and hypertrophic cardiomyopathy. …”
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Acceptance and attitudes towards COVID-19 vaccination during pregnancy in Canada by Suraya Bondy, Elisabeth McClymont, Gal Av-Gay, Arianne Albert, Janice Andrade, Sandra Blitz, Ianna Folkes, Lucia Forward, Erin Fraser, Sela Grays, Jon Barrett, Julie Bettinger, Tali Bogler, Isabelle Boucoiran, Eliana Castillo, Rohan D’Souza, Darine El-Chaâr, Shaza Fadel, Verena Kuret, Gina S. Ogilvie, Vanessa Poliquin, Manish Sadarangani, Heather Scott, John W. Snelgrove, Modupe Tunde-Byass, Deborah Money

“…SARS-CoV-2 infection in pregnancy is associated with increased risk of severe illness and adverse perinatal outcomes. However, evidence regarding the use of COVID-19 vaccines in pregnancy shows safety and efficacy. …”
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Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“…The data transfer agreement between the Pan African Centre for Epidemics Research and the Perinatal HIV Research Unit was finalized (October 2024), and we are anticipating receiving data by (December 2024). …”
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MLL4 regulates postnatal palate growth and midpalatal suture development by Jung-Mi Lee, Hunmin Jung, Bruno de Paula Machado Pasqua, Yungki Park, Qinghuang Tang, Shin Jeon, Shin Jeon, Soo-Kyung Lee, Jae W. Lee, Hyuk-Jae Edward Kwon

“…Whole-mount and histological staining at perinatal stages identified that the midline defects in the Mll4-cKO mice emerged as early as 1 day prior to birth, presenting as a widened midpalatal suture, accompanied by increased cell apoptosis in the suture mesenchyme. …”
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Lipoleiomyoma of the uterus in a woman of reproductive age (clinical case) by V.V. Talash, Ya.V. Palyokha, A.M. Gromova, V.V. Talash, V.B. Martynenko, N.O. Prylutska, N.I. Mityunina

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Transition to competent oral feeding in preterm infants: Analyzing timing and determinants by Gabriela Bolea Muguruza, Cristina de Frutos Martínez, M. Teresa Tamayo Martínez, Judith Martín Corral

“…We collected data on perinatal variables, feeding practices and complications associated with prematurity. …”
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Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis by Bo Pan, Yiming Pan, Yu-Song Huang, Meng Yi, Yuwei Hu, Xiaoyu Lian, Hui-Zhong Shi, Mingwei Wang, Guifen Xiang, Wen-Yi Yang, Zhong Liu, Fangfang Xia

“…Besides, the efficacy was shown in depressed patients without comorbidities (SMD −0.31, 95% CI [−0.40, −0.22], I 2  = 0%), whereas effectiveness was poor in those with digestive disorders, such as irritable bowel syndrome (SMD −0.37, 95% CI [−0.89, 0.16], I 2  = 74%), chronic diarrhea (SMD −0.34, 95% CI [−0.73, 0.05]), and chronic constipation (SMD −0.23, 95% CI [−0.57, 0.11], I 2  = 0%). In perinatal depressed patients, MTT was not effective (SMD 0.16, 95% CI [0.01, 0.31], I 2  = 0%). …”
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Effectiveness of the Modified WHO Labour Care Guide to Detect Prolonged and Obstructed Labour Among Women Admitted at Eight Publicly Funded, Midwife-Led Community Health Facilities... by Mugyenyi GR, Tumuhimbise W, Atukunda EC, Tibaijuka L, Ngonzi J, Kayondo M, Kanyesigye M, Musimenta A, Yarine FT, Byamugisha JK

“…Godfrey R Mugyenyi,1,2 Wilson Tumuhimbise,3 Esther C Atukunda,2,4 Leevan Tibaijuka,1 Joseph Ngonzi,1 Musa Kayondo,1 Micheal Kanyesigye,2 Angella Musimenta,3 Fajardo T Yarine,1 Josaphat K Byamugisha5 1Obstetrics and Gynaecology Department, Mbarara University of Science and Technology, Mbarara, Uganda; 2Support Mom’s Project, Mbarara University of Science and Technology, Mbarara, Uganda; 3Computing and Informatics Department, Mbarara University of Science and Technology, Mbarara, Uganda; 4Pharmacy department, Mbarara University of Science and Technology, Mbarara, Uganda; 5Obstetrics and Gynaecology department, Makerere University College of Health Sciences, Kampala, UgandaCorrespondence: Godfrey R Mugyenyi, Email gmugyenyi@must.ac.ugBackground: Obstructed labour, a sequel of prolonged labour, remains a significant contributor to maternal and perinatal deaths in low resource settings.Objective: We evaluated the modified WHO labour care guide (LCG) in detecting prolonged/obstructed labour compared to the traditional partograph at publicly funded maternity centers in Southwestern Uganda.Methods: LCG was deployed to monitor labour by trained health care providers in 2023. …”
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Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients by Yan Cao, Lanlan Meng, Yifei Wang, Shenglong Zhao, Yuanyuan Zheng, Rui Ran, Jie Du, Hongqiang Wu, Jiaqi Han, Zhengwen Xu, Yifan Lu, Lin Liu, Lu Chen, Jing Wang, Youran Li, Yanhong Zhai, Zhi Sun, Zheng Cao

“…Abstract Preeclampsia (PE) is a serious pregnancy complication that contributes to maternal and perinatal morbidity and mortality. Understanding its pathogenesis and revealing predictive biomarkers are essential for guiding treatment decisions. …”
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In situ simulation for cardiopulmonary resuscitation training: A systematic review by Andrea Cortegiani, Mariachiara Ippolito, Cristian Abelairas-Gómez, Sabine Nabecker, Alexander Olaussen, Kasper G. Lauridsen, Yiqun Lin, Taylor Sawyer, Joyce Yeung, Andrew S. Lockey, Adam Cheng, Robert Greif, Aaron Donoghue, Barbara Farquharson, Chih-Wei Yang, Heike Geduld, Kathryn Eastwood, Kevin Nation, Sebastian Sch naubelt, Tasuku Matsuyama, Ying-Chih Ko, Katherine S. Allen, Tracy Kidd, Jan Breckwoldt, Ming-Ju Hsieh

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Individual participant data meta-analysis of trials comparing frozen versus fresh embryo transfer strategy (INFORM): a protocol by Lan N Vuong, Rui Wang, Ben W Mol, Rong Li, Karin Hammarberg, Kate Brian, Yun Sun, Pollyanna Hardy, Anja Pinborg, Siladitya Bhattacharya, Sacha Stormlund, David J McLernon, Zi-Jiang Chen, Richard S Legro, Carlos Simon, Shimona Lai, Marian G Showell, Daimin Wei, Ze Wang, Keliang Wu, Xavier Santamaría, Christophe Blockeel, Femke Mol, Anna P Ferraretti, Bruce S Shapiro, Forest C Garner, Christos A Venetis, Abha Maheshwari, Gwenda Burns

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School-based mindfulness training in early adolescence: what works, for whom and how in the MYRIAD trial? by Susan Ball, Obioha C Ukoumunne, Tamsin Ford, Sarah Byford, Tim Dalgleish, Willem Kuyken, Jesus Montero-Marin, Kate Tudor, Alice Tickell, Catherine Crane, Ariane Petit, Elise Sellars, Laura Taylor, Maris Vainre, Benjamin Jones, Kirsty Griffiths, Elizabeth Nuthall, J Mark G Williams, Sarah-Jayne Blakemore, Katie Fletcher, Emma Medlicott, Anam Raja, Matthew Allwood, Louise Aukland, Tríona Casey, Nicola Dalrymple, Katherine De Wilde, Eleanor-Rose Farley, Jennifer Harper, Nils Kappelmann, Maria Kempnich, Liz Lord, Lucy Palmer, Alice Philips, Isobel Pryor-Nitsch, Lucy Radley, Anna Sonley, Jem Shackleford, Mark T Greenberg, Verena Hinze, Saz Ahmed, Marc Bennett, Lucy Foulkes, Cait Griffin, Konstantina Komninidou, Rachel Knight, Suzannah Laws, Jovita Leung, Jenna Parker, Blanca Piera Pi-Sunyer, Ashok Sakhardande, Lucy Warriner, Brian Wainman

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Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study by Marieke Bierhoff, Chaisiri Angkurawaranon, Aung Myat Min, Mary Ellen Gilder, Nay Win Tun, Arunrot Keereevijitt, Aye Kyi Win, Elsi Win, Verena Ilona Carrara, Tobias Brummaier, Cindy S. Chu, Laurence Thielemans, Kanlaya Sriprawat, Borimas Hanboonkunupakarn, Marcus Rijken, François Nosten, Michele van Vugt, Rose McGready

“…Hepatitis B virus (HBV) was believed to have minimal impact on pregnancy outcomes apart from the risk of perinatal transmission. In more recent years, there have been reports of adverse associations, most consistently preterm birth (PTB), but this is in the context of high rates of caesarean section. …”
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Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study by Alba Casellas, Cristina Martínez, Judit Amigó, Roser Ferrer, Laia Martí, Carme Merced, Maria Carmen Medina, Istria Molinero, Marta Calveiro, Anna Maroto, Ester del Barco, Elena Carreras, Maria Goya

“…<b>Background:</b> To evaluate the impact of applying alternative diagnostic criteria for gestational diabetes mellitus (GDM) during the COVID-19 pandemic on GDM prevalence, obstetrical and perinatal outcomes, and costs, as compared to the standard diagnostic method. …”
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Acute respiratory tract infections during the first 6 years of life – results from the German birth cohort study LoewenKIDS by Bianca Klee, Sophie Diexer, Susan Langer, Cornelia Gottschick, Carla Hartmann, Nadine Glaser, Johannes Horn, Evelyn Dorendorf, Heike Raupach-Rosin, Lamiaa Hassan, Nicole Rübsamen, Kristin Maria Meyer-Schlinkmann, Carlos A. Guzman, Valerie Heselich, Eva Battin, Thomas Pietschmann, Dietmar H. Pieper, Mathias Pletz, Peggy Riese, Stephanie Trittel, Saskia Thies, Constantin von Kaisenberg, Frank Dressler, Florian Guthmann, Carsten Oberhoff, Ralf L. Schild, Andre Karch, Rafael Mikolajczyk

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Implementation of in utero laparotomy-assisted fetoscopic spina bifida repair in two centers in Latin America: rationale for this approach in this regionAJOG Global Reports at a Gl... by Jezid Miranda, PhD, Miguel A. Parra-Saavedra, PhD, William O. Contreras-Lopez, PhD, Cristóbal Abello, MD, Guido Parra, MD, Juan Hernandez, MD, Amanda Barrero, MD, Isabela Leones, MD, Adriana Nieto-Sanjuanero, MD, Gerardo Sepúlveda-Gonzalez, MD, Magdalena Sanz-Cortes, PhD

“…These findings support the broader adoption of fetoscopic SB repair in regions with a high prevalence of SB and suboptimal perinatal outcomes, underscoring its advantages over hysterotomy-based approaches.…”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23rd-26th, 2024 CHILDREN’S HEALTH: MESSAGES FROM THE FUTURE   The Workshop has been organized with the patronage of Autonomous Region of Sardinia, City of Cagliari, Azienda Ospedaliera di Cagliari, University of Cagliari, Board of Physicians of the Province of Cagliari, Italian-Albanian Pediatric Society, AMBO (Alleanza per un Ambiente a misura di Bambino: alliance for a child-friendly environment), European Project Better4u, European Project Life Milch, National Confederation of Pediatrics Heads (CONAPP), Italian Federation of Family Pediatricians (FIMP), Italian-Arabian Pediatric Society (IAPS), Italian-Romanian Pediatric Society (IRPS), Norman Group of Neonatal and Pediatric Nephrology, International Academy of Perinatal Medicine, Italian Society of Pediatric Allergology and Immunology (SIAIP), Italian Society of Clinical Biochemistry (SIBioC), Italian Society of Gynecology of Infancy and Adolescence (SIGIA), Italian Society of Neonatology (SIN), Italian Society of Hospital Pediatricians (SIPO), Association SIPO in the World, Italian Society of Developmental Origins of Health and Disease (SI-DOHaD), Alfred Nobel International Study Center Sanremo, Italian Society of Pediatricians (SIMPE), Italian Society of Pediatric Psychology (S.I.P.Ped.), Romanian Society of Pediatrics, Italian Society for Research on Essential Oils (SIROE), Italian Society of Neonatal Nursing (SIN INF), Union of European Neonatal and Perinatal Societies (UENPS).   …”
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