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    Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production by Parnian Arafi, Sujan Devkota, Emily Williams, Masato Maesako, Michael S Wolfe

    Published 2025-02-01
    “…However, proteolysis of APP substrate by γ-secretase is processive, involving initial endoproteolysis to produce long Aβ peptides of 48 or 49 residues followed by carboxypeptidase trimming in mostly tripeptide increments. …”
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  3. 123

    Insights to Clinical Use of Serial Determination in Titers of Cyclic Citrullinated Peptide Autoantibodies by Toshiaki Kogure, Takeshi Tatsumi, Hiroshi Fujinaga, Atsushi Niizawa, Katsutoshi Terasawa

    Published 2007-01-01
    “…Anti-cyclic citrullinated peptide (CCP) antibody is a useful marker for the diagnosis and prognosis of rheumatoid arthritis (RA). …”
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    Molecular Mechanism of Targeted Inhibition of Pancreatic Lipase and Cholesterol Esterase by Hempseed Peptides by YIN Hao, ZHU Jiangxiong, ZHAO Haiyun, ZHONG Yu, WANG Danfeng, DENG Yun

    Published 2025-01-01
    “…Further analysis using molecular docking simulations showed that hydrogen bonding, salt bridges, and cation-π interactions played crucial roles in peptide-enzyme binding. This study enriches our understanding of the interaction mechanism of peptides with PL and CE, and provides a scientific basis for the development of functional foods based on hempseed protein.…”
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  7. 127

    Computer simulation of the spatial structure of MUC 1 peptides capable of inhibiting apoptosis by N. V. Ivanisenko, I. N. Lavrik, V. A. Ivanisenko

    Published 2016-01-01
    “…The main focus of the work was given to the peptide MUC1-CD (46-72), which is capable of binding to FA DD. …”
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    Synthesis of Novel Peptide Dendrimers PDL-GB2 and PDL-G2 by Lin Yunzhu, Weng Lingling, Qi Qingrong

    Published 2015-01-01
    “…Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. …”
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    Peptide Design for Enhanced Anti-Melanogenesis: Optimizing Molecular Weight, Polarity, and Cyclization by Putri SA, Maharani R, Maksum IP, Siahaan TJ

    Published 2025-01-01
    “…It was found that optimal peptide size was within the range of 400– 600 Da. …”
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  14. 134

    Dietary selenium peptide supplementation for increasing the growth of African catfish Clarias gariepinus by Muhammad Agus Suprayudi, Muhammad Roikhan Amanullah, Dedi Jusadi, Hasan Nasrullah, Ahmad Yazid Latif

    Published 2023-04-01
    “…The results showed that the final biomass of catfish fed with selenium peptide was significantly different (p<0.05) from catfish fed without selenium peptide, with a value of 1147,50 g and 96,67% of survival rate. …”
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    C-Peptide Levels Predict the Effectiveness of Dipeptidyl Peptidase-4 Inhibitor Therapy by Sevin Demir, Sule Temizkan, Mehmet Sargin

    Published 2016-01-01
    “…These effects depend on baseline C-peptide levels.…”
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    Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis by Victor E. Reviglio, Ruben H. Sambuelli, Alejandra Olmedo, Micaela Falco, Jose Echenique, Terrence P. O'Brien, Irene C. Kuo

    Published 2007-01-01
    “…To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity, in the innate ocular immune reaction in a rat model of Staphylococcus aureus endophthalmitis. …”
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