Primary Bone Marrow B-Cell Lymphoma Undetected by Multiple Imaging Modalities That Initially Presented with Hypercalcemia by Jin Sae Yoo, Juwon Kim, Hyeong Ju Kwon, Jung Soo Lim

“…To exclude malignancy, we performed imaging studies, including abdomen or chest computed tomography and positron emission tomography-computed tomography; however, no suspicious lesion was found, although the serum PTH-related peptide level was elevated at 4.0 pmol/L. A bone marrow biopsy was performed to identify any hidden hematologic malignancy. …”
Get full text

Predictors of Hospital Length of Stay among Patients with Low-risk Pulmonary Embolism by Li Wang, Onur Baser, Phil Wells, W. Frank Peacock, Craig I. Coleman, Gregory J. Fermann, Jeff Schein, Concetta Crivera

“…Those with troponin I (OR: 0.7, 95% CI: 0.54-0.86) or natriuretic peptide testing (OR: 0.7, 95% CI: 0.57-0.90), or more comorbidities at baseline, were less likely to have short length of stay. …”
Get full text

Molecular Mechanisms of Alzheimer’s Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for... by Eun Hee Ahn, Jae-Bong Park

“…Amyloid-β peptide (Aβ) is a critical cause of Alzheimer’s disease (AD). …”
Get full text

Interaction of Cu(II) and Ni(II) with Ypk9 Protein Fragment via NMR Studies by Massimiliano Francesco Peana, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi, Maria Antonietta Zoroddu

“…Structural changes in the conformation of the peptide with organized side chain orientation promoted by nickel coordination were detected.…”
Get full text

Fulminant Diabetes in a Patient with Advanced Melanoma on Nivolumab by Nora Chokr, Hafsa Farooq, Elizabeth Guadalupe

“…Hemoglobin A1C was 6.9%. C-peptide was undetectable (<0.1 ng/ml). Glutamic acid decarboxylase autoantibodies, zinc transporter 8 autoantibodies, insulin autoantibodies, islet antigen 2 autoantibodies, and islet cell antibodies were all negative. …”
Get full text

The Effects of Six Weeks of Endurance Training and CGRP Inhibition on Nrf2 and AKT Expression in the Hippocampal Tissue of Male Wistar Rats by Maryam Zare, Shila Nayebifar, Soheil Aminizadeh, Majid Vahidian-Rezazadeh

“…To study the effects of a six-week endurance training protocol and calcitonin gene-related peptide (CGRP) inhibition on the nuclear factor erythroid 2-related factor 2 (Nrf2) and protein kinase B (PKB) or AKT expression in the hippocampal tissue of male Wistar rats. …”
Get full text

Long-Term Metabolic Outcomes after Gestational Diabetes Mellitus (GDM): Results from the Odense GDM Follow-Up Study (OGFUS) by Kristine Hovde Jacobsen, Jori Aalders, Katrine Sølling, Marianne Skovsager Andersen, Lena Sønder Snogdal, Maria Hornstrup Christensen, Christina Anne Vinter, Kurt Højlund, Dorte Møller Jensen

“…In total, 128 women with pGDM (median follow-up: 7.8 years) and 70 non-GDM controls (median follow-up: 10.0 years) completed a 2 h oral glucose tolerance test (OGTT) with assessment of glucose, C-peptide, insulin, and other metabolic measures. Additionally, anthropometrics, fat mass, and blood pressure were assessed and indices of insulin sensitivity and beta cell function were calculated. …”
Get full text

Saturated lysing efficiency of CD8+ cells induced monostable, bistable and oscillatory HIV kinetics by Shilian Xu

“…Effector CD8+ cells lyse human immunodeficiency viruses (HIV)-infected CD4+ cells by recognizing a viral peptide presented by human leukocyte antigens (HLA) on the CD4+ cell surface, which plays an irreplaceable role in within-host HIV clearance. …”
Get full text

Syndecan-4 is More Sensitive in Detecting Hypertensive Left Ventricular Diastolic Dysfunction in 2K2C Rats by Wenyue Dai, Yanqiu Liu, Fengjuan Yao, Wei Li, Jia Liu, Cuiling Li, Donghong Liu

“…The aim of this study was to investigate the changes of syndecan-4 (SDC-4) during the hypertensive period in two kidney-two clip (2K2C) hypertension rats and compare them to brain natriuretic peptide (BNP) and the echocardiographic parameters for diastolic function evaluation in the rat model of 2K2C hypertension. …”
Get full text

Simplified MS2 phage-like particle production including a novel maturation protein internal fusion affinity tag by Enos C. Kline, Rose Duong, Qin Wang, Barry R. Lutz

“…This advancement increases the number of available peptide display sites for the MS2 PLP platform with wide-ranging implications for future applications.…”
Get full text

Properties, Antioxidant and Antibacterial Activity of Southern Meagre Fish (<i>Argyrosomus hololepidotus</i>) Skin Gelatin Reinforced with Clove Bud Extract by Parvin Rostami, Ali Taheri, Mostafa Ghaffari

“…It can be concluded that phenolic compounds, such as eugenol in the clove extract, facilitated the formation of additional bonds between the peptide helixes of the gelatin, thereby enhancing the properties of the CE-incorporated films. …”
Get full text

Xanthomonas citri subsp. citri requires a polyketide cyclase to activate the type III secretion system for virulence by Shuying Zhu, Siyu Wu, Yanmin Liu, Zaibao Zhang, Huasong Zou

“…Results The PKC was determined to have a signal peptide, a START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) domain, and a GyrI-like small molecule binding domain. …”
Get full text

Potential Antimicrobe Producer of Endophytic Bacteria from Yellow Root Plant (Arcangelisia flava (L.)) Originated from Enggano Island by null Sipriyadi, null Masrukhin, Risky Hadi Wibowo, Welly Darwis, Salprima Yudha, Ismu Purnaningsih, Resli Siboro

“…These four isolates are identified as able to produce the bioactive compounds through the detection of polyketide synthase (PKS) and nonribosomal peptide synthase (NRPS)-encoding genes. B. cereus AKEBG23 has the highest inhibition against pathogenic bacteria, and according to the GC-MS analysis, five major compounds are allegedly involved in its antimicrobial activity such as butylated hydroxytoluene (BHT), diisooctyl phthalate, E-15-heptadecenal, 1-heneicosanol, and E-14-hexadecenal. …”
Get full text

Identification and Characterization of Novel Perivascular Adventitial Cells in the Whole Mount Mesenteric Branch Artery Using Immunofluorescent Staining and Scanning Confocal Micro... by Chandra Somasundaram, Rahul K. Nath, Richard D. Bukoski, Debra I. Diz

“…A novel perivascular adventitial cell termed, adventitial neuronal somata (ANNIES) expressing the neural cell adhesion molecule (NCAM) and the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP), exists in the adult rat mesenteric branch artery (MBA) in situ. …”
Get full text

КЛАССИФИКАЦИЯ И ПОДТВЕРЖДЕНИЕ АНТИМИКРОБНОЙ АКТИВНОСТИ ПИЩЕВОГО ПЕПТИДА В ЭКСПЕРИМЕНТЕ INVITRO by Сергей Леонидович Тихонов, Наталья Валерьевна Тихонова, Инга Геннадьевна Пестова, Наталия Вадимовна Мерзлякова

“…На основании идентификации пептида по базе «Antimicrobial Peptide Database» установлено, что он на 40 % подобен антимикробному пептиду AP00450, действующему губительно на грамположительные и грамотрицательные бактерии. …”
Get full text

NMR probing of copper–amyloid β1–16 interactions and self-assembly by Punnepalli Sunanda, Srinivasarao Raghothama, Uma Maheswari Devi Palempalli, Bankala Krishnarjuna

“…Atomic-level investigation of Aβ interaction with copper ions is essential for understanding the metal-mediated peptide self-assembly. In this study, we investigated copper ion–Aβ1–16 interactions using nuclear magnetic resonance (NMR) spectroscopy, circular dichroism, and transmission electron microscopy. …”
Get full text

Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase by E. S. Dyudeeva, I. A. Pyshnaya

“…The best-known completely uncharged analogs of oligonucleotides – morpholine oligonucleotides and peptide nucleic acids – cannot be substrates for enzymes that process nucleic acids. …”
Get full text

Relation of Asymmetric Dimethylarginine Levels to Macrovascular Disease and Inflammation Markers in Type 2 Diabetic Patients by Mustafa Celik, Serkan Cerrah, Mahmut Arabul, Aysen Akalin

“…We obtained fasting serum and plasma samples and measured HbA1c, fasting blood glucose, C-peptide, creatinine, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, hsCRP, fibrinogen, erythrocyte sedimentation rate, total homocysteine, and ADMA levels. …”
Get full text

Impact of Left Atrial Appendage Closure Combined with Catheter Ablation on Endocrine and Mechanical Cardiac Function in Patients with Atrial Fibrillation by Jing Yang, Ling You, Mingqing Liu, Guangming Zhang, Liang Feng, Yue Liu, Xue Geng, Jinglan Wu, Ruiqin Xie

“…During follow-up, patients were examined for brain natriuretic peptide (BNP) levels to represent endocrine cardiac function. …”
Get full text

Differences in phenotypes of normal and malignant cells concerning chromosomal fragility and ganglioside expression by Iskra Sainova, Vera Kolyovska, Desislava Drenska, Dimitar Maslarov, Dimitrina Dimitrova-Dikanarova, Tzvetanka Markova

“…Of particular interest were interactions involving gangliosides, the reduced form of tri-peptide glutathione (GSH) and/or of tumor-suppressor protein HACE1. …”
Get full text