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761
Adipocyte-Specific Fatty Acid-Binding Protein (AFABP) and Chemerin in Association with Gestational Diabetes: A Case-Control Study
Published 2021-01-01“…However, among these peptides, the role of adipocyte-specific fatty-acid-binding protein (AFABP), chemerin, and secreted protein acidic and rich in cysteine (SPARC) in gestational diabetes (GDM) has not been fully investigated. …”
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762
Polymers for the treatment of Alzheimer’s disease
Published 2025-01-01“…It is a neurodegenerative disorder, and its main clinical symptoms include the loss of established memories, a decline in learning capacity, and the buildup of β-amyloid peptides. The disease is often accompanied by neurodegenerative changes and the formation of neurofibrillary tangles. …”
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763
Are Ancient Durum Wheats Less Toxic to Celiac Patients? A Study of α-Gliadin from Graziella Ra and Kamut
Published 2012-01-01“…Experiments were carried out with two monoclonal antibodies (mAbs) raised against α-gliadin peptides p31–49 and p56–75 (the latter containing the overlapping DQ2-Glia-α1 and DQ2-Glia-α2 epitopes), toxic for celiac patients. …”
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764
Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides
Published 2014-01-01“…We investigated the kinetics of 4N-acetyl-pentapeptides, Ac-P1, Ac-P2, Ac-P3, and Ac-P4, regarding inhibition of mushroom tyrosinase activity. The peptides sequences of Ac-P1, Ac-P2, Ac-P3, and Ac-P4 were Ac-RSRFK, Ac-KSRFR, Ac-KSSFR, and Ac-RSRFS, respectively. …”
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765
Fermentation dynamics of millet beverages: Microbial interactions, nutritional enhancements, and health implications
Published 2025-01-01“…It also enhances the synthesis of vitamins, minerals, and peptides, offering potential benefits for managing chronic conditions. …”
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766
PaleoProPhyler: a reproducible pipeline for phylogenetic inference using ancient proteins
Published 2023-11-01“…Here, we present PaleoProPhyler: a new fully reproducible pipeline for aligning ancient peptide data and subsequently performing phylogenetic analyses. …”
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767
Identification and Characterization of TEX101 in Bovine Epididymal Spermatozoa
Published 2014-01-01“…Proteomic identification yielded ten peptides that matched the sequence of Testis Expressed 101 protein (TEX101). …”
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768
Characterization of the Hypercitrullination Reaction in Human Neutrophils and Other Leukocytes
Published 2015-01-01“…Other neutrophil activating stimuli, such as formyl-peptides, GM-CSF, IL-6, IL8, TNFα, or phorbol ester, did not induce any detectable increase in protein citrullination, suggesting that receptor-induced calcium mobilization is insufficient to trigger hypercitrullination. …”
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769
Assessing the Proteomic Activity of the Venom of the Ant Ectatomma tuberculatum (Hymenoptera: Formicidae: Ectatomminae)
Published 2018-01-01“…., proteins such as phospholipases, hyaluronidases, and proteinases, as well as peptides. Protein databases show that information on protein components of ant venoms has been recently growing exponentially. …”
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770
Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques
Published 2025-01-01“…Rapid advances in the field of NS could resolve issues related to permeability-limited absorption and hepatic first-pass metabolism, offering promise for medications based on proteins and peptides. The evolution of novel stabilizers is essential to overcome the current limitations in NS formulations, enhancing their stability, bioavailability, targeting ability, and safety profile, which ultimately accelerates their clinical application and commercialization.…”
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771
Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases
Published 2014-11-01“…The capability of bacteria contact with immune cells is provided by capacity of bacterial cells to adhesion and invasion, competence of mucus layer covering mucosa of gastro-intestinal tract, detaining and fixing microbic cells, competence of intercellular epithelial contacts function, density of signal receptors, level of antimicrobic peptides expression, completeness of autophagy process. …”
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772
In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-)
Published 2007-01-01“…We reported that regioselectively addressable functionalized template (RAFT)-c(-RGDfK-) 4 presenting four cyclic (Arg-Gly-Asp) (cRGD) peptides targets integrin a V b 3 with an improved specificity compared with monomeric cRGD. …”
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773
Paneth Cells: Dispensable yet Irreplaceable for the Intestinal Stem Cell NicheSummary
Published 2025-01-01“…Although Paneth cells were first described as an epithelial cell component of the innate immune system due to their expression of anti-microbial peptides, they have been proposed to be niche cells due to their close proximity to intestinal stem cells and expression of niche factors. …”
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774
Cerebral Epiphyseal Proteins and Melatonin Modulate the Hepatic and Renal Antioxidant Defense of Rats
Published 2011-01-01“…The cerebral epiphysis (pineal gland) secrets melatonin and number of other proteins and peptides. It was thus hypothesized that antioxidant properties of epiphyseal proteins and melatonin could potentially benefit from exogenous therapies. …”
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775
Activation of Vitamin D Regulates Response of Human Bronchial Epithelial Cells to Aspergillus fumigatus in an Autocrine Fashion
Published 2015-01-01“…Locally activated vitamin D amplified SC-induced expression of antimicrobial peptides in 16HBE cells but attenuated SC-induced production of cytokines in an autocrine fashion. …”
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776
INHIBITION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) BIOFILM: THE ESSENTIAL ROLE AND POTENTIAL USAGE OF BACTERIOCINS
Published 2024-07-01“…According to reports, bacteriocins, such as peptides synthesized by Gram-negative and Gram-positive bacteria, have antimicrobial activity that has the potential to inhibit antibiotic-resistant pathogens and biofilms formed by MRSA. …”
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777
XGBoost-enhanced ensemble model using discriminative hybrid features for the prediction of sumoylation sites
Published 2025-02-01“…The model utilizes a transformer-based attention mechanism to encode peptides and extract evolutionary features through the PsePSSM-DWT approach. …”
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778
Non-viral systems for intracellular delivery of genome editing tools
Published 2024-04-01“…This work reviews abiotic vectors and systems for delivering genome editing tools into target cells, including liposomes and solid lipid particles, other membrane-based vesicles, cell-penetrating peptides, micelles, dendrimers, carbon nanotubes, inorganic, polymer, metal and other nanoparticles. …”
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779
Amylin: Localization, Effects on Cerebral Arteries and on Local Cerebral Blood Flow in the Cat
Published 2001-01-01“…Amylin and adrenomedullin are two peptides structurally related to calcitonin gene-related peptide (CGRP). …”
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780
The Interplay between Defensins and Microbiota in Crohn’s Disease
Published 2017-01-01“…Several studies have shown defective expression of intestinal antimicrobial peptides (AMPs) in patients with CD compared to controls, particularly defensins. …”
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