Antioxidant and Chelating Activity of Nontoxic Jatropha curcas L. Protein Hydrolysates Produced by In Vitro Digestion Using Pepsin and Pancreatin by Santiago Gallegos Tintoré, Cristina Torres Fuentes, Javier Solorza Feria, Manuel Alaiz, Julio Girón Calle, Alma Leticia Martínez Ayala, Luis Chel Guerrero, Javier Vioque

“…These fractions were characterized by a large presence of peptides with different molecular masses. The hydrolysates exhibited both Cu2+ and Fe2+ chelating activity. …”
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Enzymatic Hydrolysis Systems Enhance the Efficiency and Biological Properties of Hydrolysates from Frozen Fish Processing Co-Products by Maria Sapatinha, Carolina Camacho, Antónia Juliana Pais-Costa, Ana Luísa Fernando, António Marques, Carla Pires

“…This study highlights the value of fish co-products as sources of functional peptides, contributing to waste reduction, and their potential applications in food, agriculture, and nutraceuticals.…”
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Neurobiology of Major Depressive Disorder by Rosa Villanueva

“…Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling network, which includes the hypothalamic-pituitary-adrenal axis; the production of neurotrophins and growth factors; the expression of miRNAs; the production of proinflammatory cytokines; and, even, the abnormal delivery of gastrointestinal signaling peptides, are able to induce major mood alterations. …”
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Immunotherapeutic Strategies for Alzheimer's Disease Treatment by Beka Solomon

“…Active and/or passive immunization against the amyloid-β peptide has been proposed as a method for preventing and/or treating AD. …”
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Cytokines and Liver Diseases by Herbert Tilg

“…Cytokines are pleiotropic peptides produced by virtually every nucleated cell in the body. …”
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Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds by Noor Atatreh, Radwa E. Mahgoub, Mohammad A. Ghattas

“…Peptidomimetic inhibitors mimic natural peptide substrates, employing electrophilic warheads to covalently interact with the catalytic Cys145 of Mpro. …”
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The Use of N-Terminal-Pro-BNP in Preterm Infants by Afif EL-Khuffash, Eleanor Molloy

“…The use of natriuretic peptides in the neonatal population is emerging. B-type Natriuretic Peptide (BNP) and N-terminal-Pro-BNP (NTpBNP) are used in the adult population to assess myocardial function and volume loading. …”
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Development of Class IIa Bacteriocins as Therapeutic Agents by Christopher T. Lohans, John C. Vederas

“…Class IIa bacteriocins have been primarily explored as natural food preservatives, but there is much interest in exploring the application of these peptides as therapeutic antimicrobial agents. Bacteriocins of this class possess antimicrobial activity against several important human pathogens. …”
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Small Bowel Review: Part II by ABR Thomson, JA Thomson, MJ Ropeleski, GE Wild

“…Topics discussed are enterocyte proliferation and growth factors; amino acids, peptides and allergies; motility; salt and water absorption and secretion – diarrhea; vitamins and minerals; early development and ageing of the intestine; and ethanol effects.…”
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The Role of the Estimated Plasma Volume Variation in Assessing Decongestion in Patients with Acute Decompensated Heart Failure by Andreea-Maria Grigore, Mihai Grigore, Ana-Maria Balahura, Gabriela Uscoiu, Ioana Verde, Camelia Nicolae, Elisabeta Bădilă, Adriana-Mihaela Ilieșiu

“…Conclusions: Indirect estimation of plasma volume and its variation are valuable, accessible, and cost-effective parameters for assessing decongestive treatment in ADHF patients, complementing natriuretic peptides.…”
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Biological evaluation and interaction mechanism of beta-site APP cleaving enzyme 1 inhibitory pentapeptide from egg albumin by Zhipeng Yu, Sijia Wu, Wenzhu Zhao, Long Ding, David Shiuan, Fuping Zheng, Jianrong Li, Jingbo Liu

“…Then, molecular docking and molecular dynamics simulation were used to explain the molecular mechanism of the interactions between BACE1 and peptides. The IC50 value of peptide KLPGF, with satisfactory ADMET properties, against BACE1 was (8.30 ± 0.56) mmol/L. …”
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A Review on Factors Influencing the Fermentation Process of Teff (Eragrostis teff) and Other Cereal-Based Ethiopian Injera by Yizengaw Mengesha, Alemu Tebeje, Belay Tilahun

“…Biogenic amines, bioactive peptides, antinutrient reduction, and polyphenol conversion to physiologically active chemicals are all possible health benefits of fermentation process products. …”
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Radioimmunotherapy: A Specific Treatment Protocol for Cancer by Cytotoxic Radioisotopes Conjugated to Antibodies by Hidekazu Kawashima

“…Radioimmunotherapy (RIT) represents a selective internal radiation therapy, that is, the use of radionuclides conjugated to tumor-directed monoclonal antibodies (including those fragments) or peptides. In a clinical field, two successful examples of this treatment protocol are currently extended by 90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar), both of which are anti-CD20 monoclonal antibodies coupled to cytotoxic radioisotopes and are approved for the treatment of non-Hodgkin lymphoma patients. …”
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Post-midnight versus pre-midnight surgery for patients with ruptured abdominal aortic aneurysm and the risk 1469 factors of postoperative mortality: A single-center study by Yan-Ye Hung, Qingle Li, Xuemin Zhang, Xiaoming Zhang

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High-throughput Identification of Phage-derived Imaging Agents by Kimberly A. Kelly, Paul A. Clemons, Amy M. Yu, Ralph Weissleder

“…The use of phage-displayed peptide libraries is a powerful method for selecting peptides with desired binding properties. …”
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Signal and modulating role of enzymes of digestive glands by G. F. Korotko

“…Proteinases realize effects through protease-activated receptors of four types which are localized on membranes of glandular cells, leiomyocytes, sensory terminals of afferent neurons and neuroendocrine producers of regulatory peptides, yielding direct and mediated morphofunctional effects.Conclusion. …”
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Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine by Mougin, Christiane, Rossier, Jean, Bloch, Bertrand

“…He consequently demonstrated that these brain peptides regulate a large number of major body activities through neuroendocrine mechanisms. …”
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Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases by Gunnar K. Gouras

“…However, it is not thought that the prion-like quality of these proteins/peptides that allows their cell-to-cell transmission implies a role for human-to-human spread in common age-related neurodegenerative diseases. …”
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Why Do Tetrapropylammonium Chloride and Sulphate Salts Destabilize the Native State of Globular Proteins? by Giuseppe Graziano

“…It has recently been shown that aqueous solutions of tetrapropylammonium chloride and sulphate salts destabilize the folded conformation of Trp-peptides (Dempsey et al., 2011). This result is rationalized by the application of a statistical thermodynamic approach (Graziano, 2010). …”
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Distinct phenotypes of salivaricin-producing Ligilactobacillus salivarius isolated from the gastrointestinal tract of broiler chickens and laying hens by A.G. Elnar, Y.J. Jang, B.G. Eum, M.H. Kang, G.W. Hwang, D.Y. Kil, G.B. Kim

“…Multiplex PCR analysis and synteny mapping analysis revealed that B4311 and B5258 strains harbored the lanT gene, highlighting the importance of LanT protein in the cleavage of leader peptide and excretion of mature peptides. Further analysis revealed that the resistance of Type B strains to salP was attributable to the presence of a dedicated immunity protein, blurring the evolutionary significance of producing active bacteriocins for competitive advantage. …”
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