Are Ancient Durum Wheats Less Toxic to Celiac Patients? A Study of α-Gliadin from Graziella Ra and Kamut by M. Stella Colomba, Armando Gregorini

“…Experiments were carried out with two monoclonal antibodies (mAbs) raised against α-gliadin peptides p31–49 and p56–75 (the latter containing the overlapping DQ2-Glia-α1 and DQ2-Glia-α2 epitopes), toxic for celiac patients. …”
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Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides by Ching-Yi Lien, Ching-Yu Chen, Shih-Ting Lai, Chin-Feng Chan

“…We investigated the kinetics of 4N-acetyl-pentapeptides, Ac-P1, Ac-P2, Ac-P3, and Ac-P4, regarding inhibition of mushroom tyrosinase activity. The peptides sequences of Ac-P1, Ac-P2, Ac-P3, and Ac-P4 were Ac-RSRFK, Ac-KSRFR, Ac-KSSFR, and Ac-RSRFS, respectively. …”
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Drug delivery systems for oral cancer treatment: A patent perspective by Mohamed Hassan Dehghan, Abrar Abdul Malik Siddiqui

“…Patents encompass siRNA, antibodies, immune checkpoint inhibitors, antimicrobial peptides, natural products like curcumin, nanoparticle drug carriers, and bioadhesive electrospun fibers loaded with drugs. …”
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In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-) by Zhao-Hui Jin, Jesus Razkin, Veronique Josserand, Didier Boturyn, Alexeï Grichine, Isabelle Texier, Marie-Christine Favrot, Pascal Dumy, Jean-Luc Coll

“…We reported that regioselectively addressable functionalized template (RAFT)-c(-RGDfK-) 4 presenting four cyclic (Arg-Gly-Asp) (cRGD) peptides targets integrin a V b 3 with an improved specificity compared with monomeric cRGD. …”
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INHIBITION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) BIOFILM: THE ESSENTIAL ROLE AND POTENTIAL USAGE OF BACTERIOCINS by Tati Febrianti, Conny Riana Tjampakasari

“…According to reports, bacteriocins, such as peptides synthesized by Gram-negative and Gram-positive bacteria, have antimicrobial activity that has the potential to inhibit antibiotic-resistant pathogens and biofilms formed by MRSA. …”
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Changes in basic composition and in vitro digestive characteristics of pork induced by frozen storage by Rui Wang, Yongqing Liu, Ying He, Caiping Feng, Xiufang Xia

“…During in vitro digestion of samples frozen at −8°C for 12 months, trichloroacetic acid (TCA)-soluble peptides were decreased by 25.46% and 14.37% in the gastric and small intestinal phases, respectively, compared with fresh samples. …”
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Could Hemokinin-1 (HK-1) be a Novel Candidate Biomarker for Sarcoidosis? by Turan Akdağ, Celalettin Korkmaz

“…Some studies suggest an association between peptides and sarcoidosis. The goal of the study was to investigate the biomarker values of serum hemokinin-1 (HK-1) and adropin levels in sarcoidosis and to assess their role in the disease course. …”
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Non-viral systems for intracellular delivery of genome editing tools by I. H. Shaikhutdinov, P. V. Ilyasov, O. V. Gribkova, L.  V. Limareva

“…This work reviews abiotic vectors and systems for delivering genome editing tools into target cells, including liposomes and solid lipid particles, other membrane-based vesicles, cell-penetrating peptides, micelles, dendrimers, carbon nanotubes, inorganic, polymer, metal and other nanoparticles. …”
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The Japanese encephalitis virus NS1' protein facilitates virus infection in mosquitoes. by Yuwei Liu, Yutian Huang, Ruidong Li, Chang Miao, Yi He, Changhao Xu, Xi Zhu, Bowen Li, Rui Wu, Qin Zhao, Yiping Wen, Xiaobo Huang, Qi-Gui Yan, Yi-Fei Lang, Shan Zhao, Yiping Wang, Yajie Hu, San-Jie Cao, Senyan Du

“…Specifically, the NS1' protein was found to facilitate infection through the suppression of antimicrobial peptides (AMPs) regulated by the Toll pathway.<h4>Conclusions/significance</h4>Our research demonstrated that the JEV NS1' protein contributes to immune escape, thereby enhancing viral infection in mosquitoes. …”
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Development of a unique crosslinked glycosaminoglycan for soft tissue repair: Treatment of interstitial cystitis/bladder pain syndrome. by Richard W Heidebrecht, Thomas H Jozefiak, Harrison C Shain, Eugene M Skrabut, Debra Saunders, Nataliya Smith, Rheal A Towner, Robert Hurst

“…We can optimize polymer properties, adjust adherence to various tissues, add reporters, and engage the biochemistry of surrounding tissues with peptides and other bioactives.…”
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Sex-Based Differences in the In Vitro Digestibility of MCT Emulsions Stabilized by Various Emulsifiers by Mijal Perez, Carmit Shani Levi, Uri Lesmes

“…Further, SDS-PAGE analysis of digesta showed that breakdown patterns of protein-stabilized emulsions are consistent with prior evidence found for healthy adults; however, results under female gut conditions indicated variations in protein clotting that may alter bioaccessible levels of bioactive peptides. Thus, this study underscores the importance of considering consumer biological sex in food design, especially regarding emulsion-based products for targeted digestive responses.…”
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Implementation Nutrigenomic of Vitamin D in Periodontitis by Hervina Hervina, I Dewa Made Sukrama, I Made Jawi

“…The anti-microbial effect of vitamin D results from the binding of 1,25(OH)2D3 with VDR which then induces cAMP, b-def-2 and b-def-3 peptides by macrophages, monocytes, gingival epithelium and periodontal ligament epithelium. …”
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Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins by Yan Wang, Xin Qian, Yubo Wang, Caiyuan Yu, Li Feng, Xiaoyan Zheng, Yaya Wang, Qiuhong Gong

“…Increasing the accumulation of TRAIL at tumor sites by fusing with antibody fragments or peptides; 4. Decorating immune cells with TRAIL; 5. …”
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Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice by Timothy M. Griffin, Ravi K. Komaravolu, Erika Barboza Prado Lopes, Padmaja Mehta-D’souza, Taylor Conner, Tessa Kovats, Susan Kovats, Madeline Allen, Peyton Harris, Mary Beth Humphrey, Hope D. Welhaven, Priyanka Brahmachary, Ronald K. June

“…Exercise acutely altered synovial fluid metabolites, characterized by increased amino acids, peptides, bile acids, sphingolipids, dicarboxylic acids, and straight medium chain fatty acids and decreased hydroxy fatty acids and diacylglycerols. …”
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Effects of brain renin- angiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension by L. O. Klimov, M. A. Ryazanova, L. A. Fedoseeva, A. L. Markel

“…The renin-angiotensin system (RAS) is one of the main systems regulating arterial pressure and water-salt homeostasis of the body and is involved in the pathogenesis of cardiovascular diseases. Angiotensin peptides – products of enzymatic hydrolysis of angiotensinogen – can be synthesized not only in the blood stream, but also in tissues, including various regions  of the brain. …”
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Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota by Bowen Li, Mingming Liu, Wenjing Du, Shuaidong Wang, Zekang Xu, Xiaoqian Zhang, Yang Zhang, Song Hua

“…Abstract Animals infected with mycoplasma pneumoniae not only develop respiratory diseases, but also cause digestive diseases through the lung-gut axis mediated by the intestinal flora, and vice versa. Antimicrobial peptides are characterized by their bactericidal, anti-inflammatory, and intestinal flora-regulating properties. …”
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Bifunctional copper ion/melittin incorporated hydrogel with antimicrobial and antioxidant capabilities for infected skin wound healing by Jun Yao, Xiao Li, Minjie Lin, Zhuoqi Han, Xiaonan Wang, Jingjing Guo, Bing Wu, Jiajie Xia

“…Owing to the ongoing global increase in bacterial resistance, in this study, hydrogel co-loaded with bio-antimicrobial peptides and copper ions is designed, which exhibits antimicrobial, anti-inflammatory, and antioxidant properties. the proposed, sodium alginate@copper hydrogel (SA@Cu) is formed through the cross-linking of sodium alginate and Cu2+. …”
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Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

“…Currently, there are no approved therapeutic HPV vaccines worldwide; however, active progress is being made in clinical research and development using multiple platforms such as peptides, proteins, DNA, RNA, bacterial vectors, viral vectors, and cell-based, each offering relative advantages and limitations for delivering HPV antigens and generating targeted immune responses. …”
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Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats by Peipei Dou, Xiaoyi Li, Xiaoxiao Zou, Kai Wang, Lei Yao, Zhuo Sun, Hui Hong, Yongkang Luo, Yuqing Tan

“…Novel angiotensin-converting enzyme (ACE) inhibitory peptides were identified from whey protein hydrolysates (WPH) in vitro in our previous study and the antihypertensive abilities of WPH in vivo were further investigated in the current study. …”
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Cross-sectional study of proteomic differences between moderate and severe psoriasis by Lingling Wu, Chen Cen, Bibo Xie, Lihua Hu, Jia Huang, Ningning Shen, Qiang Dong

“…The main active pathways were antimicrobial peptides and PTEN signalling, while the inhibitory pathways were the neutrophil extracellular trap pathway, neutrophil degranulation, and IL-8 signalling. 4D-parallel reaction monitoring (4D-PRM) suggested that KRT6A were downregulated in severe psoriasis. …”
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