Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery by Leonel Pereira, Ana Valado

“…This review explores the emerging field of seaweed-based drug discovery and highlights the diverse range of bioactive compounds found in seaweeds, including polysaccharides, phlorotannins, pigments, and peptides. These compounds exhibit various pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antiviral, and anticancer effects. …”
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Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases by Ye. A. Poluektova, O. S. Lyashenko, A. V. Korolev, O. S. Shifrin, V. T. Ivashkin

“…The capability of bacteria contact with immune cells is provided by capacity of bacterial cells to adhesion and invasion, competence of mucus layer covering mucosa of gastro-intestinal tract, detaining and fixing microbic cells, competence of intercellular epithelial contacts function, density of signal receptors, level of antimicrobic peptides expression, completeness of autophagy process. …”
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Hereditary Angioedema and Gastrointestinal Complications: An Extensive Review of the Literature by Napoleon Patel, Lisbet D. Suarez, Sakshi Kapur, Leonard Bielory

“…The angioedema is caused by the activation of the kallikrein-kinin system that leads to the release of vasoactive peptides, followed by edema, which in severe cases can be life threatening. …”
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Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction by Oleg Mikhajlov, Ram M. Adar, Maria Tătulea-Codrean, Anne-Sophie Macé, John Manzi, Fanny Tabarin, Aude Battistella, Fahima di Federico, Jean-François Joanny, Guy Tran van Nhieu, Patricia Bassereau

“…Unlike SLBs functionalized with RGD peptides, integrin clusters on Invasin-SLBs grow in size and complexity comparable to those on glass. …”
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Impact of dietary protein hydrolysates on cognitive performance: A systematic review of randomized controlled trials involving adults by Micah S. Adams, Ronald P. Mensink, Peter J. Joris

“…In conclusion, some studies have indicated that certain protein hydrolysates may benefit cognitive performance, but further research is needed to clarify contradictory findings and to identify beneficial bioactive peptides.…”
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Recent advances in polymeric nanoparticles for the treatment of hepatic diseases by Feng Gao, Xuefei Feng, Xinyu Li

“…Furthermore, this paper reviewed the application of polymeric nanoparticles -mainly chitosan (CS), hyaluronic acid (HA), polyethylene glycol (PEG) and poly (lactic-co-glycolic acid) (PLGA)-in liver disease treatment, focusing on their use in various delivery systems for pure bioactive compounds of natural origin, drugs, nucleic acids, peptides, and others. Finally, the challenges and future perspectives of the NPs were discussed to provide guidance for further research directions, with the aim of promoting the clinical application of nanotherapeutics in treating hepatic diseases.…”
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The Role of Immune Defects and Colonization of Staphylococcus aureus in the Pathogenesis of Atopic Dermatitis by Danuta Nowicka, Ewelina Grywalska

“…A deficiency in the endogenous antimicrobial peptides may be partly responsible for the susceptibility to colonization by and skin infection with S. aureus in patients with AD. …”
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The Potential of Secondary Metabolites in Medicinal Plants as Anti–Quorum Sensing in Biofilms: A Comprehensive Review by Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia

“…Gram-negative bacteria produce N-acyl-L-homoserine lactones as autoinducer, while quorum sensing in Gram-positive bacteria produces autoinducing peptides. By looking at quorum sensing responses in bacterial pathogenesis and resistance, the study of natural antibiotic agents became a particular concern for researchers. …”
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The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis by Animesh Singh, Sarah Karrar

“…., anticitrullinated peptides in rheumatoid arthritis), but the absence of these, in the seronegative arthritides, for example, raises question as to the underlying pathogenesis. …”
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An updated overview on the bacterial PhoP/PhoQ two-component signal transduction system by Meiqin Mao, Li He, Qingpi Yan

“…It regulates the expression of bacterial environmental tolerance genes, virulence factors, adhesion, and invasion-related genes by sensing various environmental signals in the host, including Mg2+, low pH, antimicrobial peptides, and osmotic pressure. In this review, we describe the PhoP/PhoQ system-induced signal composition and its feedback mechanism, and the abundance of PhoP phosphorylation in the activated state directly or indirectly controls the transcription and expression of related genes, regulating bacterial stability. …”
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Learning predictive signatures of HLA type from T-cell repertoires. by María Ruiz Ortega, Mikhail V Pogorelyy, Anastasia A Minervina, Paul G Thomas, Thierry Mora, Aleksandra M Walczak

“…T cells recognize a wide range of pathogens using surface receptors that interact directly with peptides presented on major histocompatibility complexes (MHC) encoded by the HLA loci in humans. …”
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A Chromosome level assembly of pomegranate (Punica granatum L.) variety grown in arid environment by Himanshu V. Patankar, Luis F. Rivera, Fatima Omari Alzahrani, Rod A. Wing, Ikram Blilou

“…The new reference genome will contribute to identifying stress resistance traits in pomegranates thriving in arid environments as well as new dietary antioxidants and antimicrobial peptides with pharmaceutical and therapeutic applications.…”
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Bariatric Endocrinology: Principles of Medical Practice by J. Michael Gonzalez-Campoy, Bruce Richardson, Conor Richardson, David Gonzalez-Cameron, Ayesha Ebrahim, Pamela Strobel, Tiphani Martinez, Beth Blaha, Maria Ransom, Jessica Quinonez-Weislow, Andrea Pierson, Miguel Gonzalez Ahumada

“…In addition to the well-established metabolic complications of overweight and obesity, adiposopathy leads to hyperinsulinemia, hyperleptinemia, hypoadiponectinemia, dysregulation of gut peptides including GLP-1 and ghrelin, the development of an inflammatory milieu, and the strong risk of vascular disease. …”
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A Narrative Review of Biomarkers and Imaging in the Diagnosis of Acute Aortic Syndrome by Ümit Arslan, Izatullah Jalalzai

“…Because AAS can be asymptomatic or present with diverse symptoms, its diagnosis requires clinical evaluation, risk scoring, and biomarkers such as D-dimer (DD), C-reactive protein (CRP), homocysteine, natriuretic peptides (BNP), and imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI), and echocardiography. …”
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Regulation of Chemokine Production via Oxidative Pathway in HeLa Cells by Shinichiro Kina, Toshiyuki Nakasone, Hiroyuki Takemoto, Akira Matayoshi, Shoko Makishi, Nao Sunagawa, Feixin Liang, Thongsavanh Phonaphonh, Hajime Sunakawa

“…At inflamed sites, neutrophils deploy a potent antimicrobial arsenal that includes proteinases, antimicrobial peptides, and ROS. Reactive oxygen species (ROSs) induce chemokines. …”
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Chronic Kidney Disease, Obesity, and Hypertension: The Role of Leptin and Adiponectin by M. Tesauro, A. Mascali, O. Franzese, S. Cipriani, C. Cardillo, N. Di Daniele

“…Remarkable improvements have been recently achieved in the study of the endocrine features of the adipose tissue and have been able to produce hormone-like peptides named adipokines or adipocytokines. Among these adipocytokines, which represent a link between obesity, hypertension, and chronic nephropathy, leptins and adiponectin appear to play an important role. …”
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Behçet's Disease (Adamantiades-Behçet's Disease) by Fumio Kaneko, Ari Togashi, Sanae Saito, Hideo Sakuma, Noritaka Oyama, Koichiro Nakamura, Kenji Yokota, Keiji Oguma

“…On the other hand, some peptides of Hsp-65 were found to reduce IL-8 and IL-12 production from PBMCs of ABD patients in active stage.…”
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Research Progress on Bacteriocins Produced by Lactic Acid Bacteria and Their Inhibitory Effect on the Biofilm of Staphylococcus aureus by Xiaoge XUE, Yuanyuan LIU, Lina ZHANG, Rui FAN, Yu XIN, Jiage MA, Wei YU, Libo LIU

“…Its biofilm formation poses a serious threat to food processing and food safety. Bacteriocins are peptides with antimicrobial activity produced by lactic acid bacteria (LAB) during metabolism. …”
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Targeting TLR/IL-1R Signalling in Human Diseases by Maria Loiarro, Vito Ruggiero, Claudio Sette

“…In particular, we will focus on inhibitors, such as decoy peptides and synthetic mimetics, that interfere with protein-protein interactions between signalling molecules of the TLR/IL-1R superfamily. …”
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Supercharged nanoadhesive through co-assembly of recombinant protein and tetrahedral DNA for corneal transplantation by Jing Zhao, Feng Zhang, Zhe Zhang, Zhenhua Li, Yanze Yu, Bingqing Sun, Binghong Yu, Yong Ma, Xuan Ding, Liyin Wang, Lifei Zheng, Wenguo Cui, Xingtao Zhou

“…After modification with RGD peptides, the adhesive system significantly enhanced corneal epithelialization, reduced inflammation and neovascularization, and ultimately promoted corneal repair. …”
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