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    Unlocking the potential of antimicrobial peptides: Beta-defensins and the future of cancer diagnostics by Saranya Velmurugan, Gowtham Kumar Subbaraj

    Published 2024-09-01
    “…Beta-defensins, a group of antimicrobial peptides crucial for innate immunity, have been linked to oral cancer development. …”
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    Article
  3. 103

    Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells by Steven Timmermans, Steven Timmermans, Charlotte Wallaeys, Charlotte Wallaeys, Somara De Beul, Somara De Beul, Natalia Garcia-Gonzales, Natalia Garcia-Gonzales, Claude Libert, Claude Libert

    Published 2025-02-01
    “…IntroductionIn mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells.MethodsWe used 148 publicly available bulk RNA-seq samples on purified PCs, proteomics on enriched purified PC proteins and Defa peptide activity assays to detect all Defa transcrips, including potential chimeric transcrips.ResultsWe identified 28 expressed Defa genes in mice, with up to 85% of Paneth cell RNA reads mapping to these genes. …”
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    A synthetic cyclic peptide for promoting antigen presentation and immune activation by Jiahui Zhang, Harrison Y. R. Madge, Asmaa Mahmoud, Lantian Lu, Wanyi Wang, Wenbin Huang, Prashamsa Koirala, Jazmina L. Gonzalez Cruz, Wei Yang Kong, Sahra Bashiri, Ahmed O. Shalash, Waleed M. Hussein, Zeinab G. Khalil, James W. Wells, Istvan Toth, Rachel J. Stephenson

    Published 2025-01-01
    “…Abstract Cyclic peptides are often used as scaffolds for the multivalent presentation of drug molecules due to their structural stability and constrained conformation. …”
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    Article
  6. 106

    Oncolytic immunotherapy: multiple mechanisms of oncolytic peptides to confer anticancer immunity by Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang

    Published 2022-07-01
    “…Therefore, this commentary discusses the broad effects and perspectives of oncolytic peptides on anticancer immunity, further highlighting the potential issues and directions of oncolytic peptides in cancer immunotherapy.…”
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    Article
  7. 107

    Prognostic Value of Adrenomedullin and Natriuretic Peptides in Uroseptic Patients Induced by Ureteroscopy by Wei Hu, Pang-hu Zhou, Wei Wang, Lijun Zhang, Xiao-bin Zhang

    Published 2016-01-01
    “…Plasma concentrations of the three peptides were correlated with plasma ET concentration in the uroseptic patients. …”
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    Article
  8. 108

    Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury by Nenad Milošević, Marie Rütter, Yvonne Ventura, Valeria Feinshtein, Ayelet David

    Published 2025-01-01
    “…Methods: P-Esbp was synthesized by conjugating E-selecting binding peptide (Esbp) to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer with reactive ester groups via aminolysis. …”
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    Article
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    Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes by Jun Sumaoka, Hiroki Akiba, Makoto Komiyama

    Published 2016-01-01
    “…Simply by adding these TbIII complexes to the solutions, phosphorylation of tyrosine in peptides by protein tyrosine kinases and dephosphorylation by protein tyrosine phosphatases can be successfully visualized in a real-time fashion. …”
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    Article
  11. 111

    Small peptides from non-edible fish waste with antimicrobial activity by Wonganu Benjamaporn, Roytrakul Sittiruk

    Published 2025-01-01
    “…They can be used to produce various value-added products such as bioactive peptides. This research produced low molecular weight antimicrobial peptides from Tuna protein hydrolysates which were hydrolyzed via pepsin. …”
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    Article
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    Coupling Strategies for the Synthesis of Peptide-Oligonucleotide Conjugates for Patterned Synthetic Biomineralization by Joshua D. Carter, Thomas H. LaBean

    Published 2011-01-01
    “…This work describes preparation strategies for peptide-oligonucleotide conjugates that combine the self-assembling behavior of DNA oligonucleotides with the molecular recognition capabilities of peptides. …”
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    Article
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    Roles of NET Peptides With Known Antimicrobial Activity and Toxicity in Immune Response by Sinan Cebeci, Tuba Polat, Nihan Ünübol

    Published 2024-01-01
    “…Antimicrobial peptides (AMPs) are crucial components of the innate immune system in all living organisms, playing a vital role in the body’s defense against diseases and infections. …”
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    Article
  17. 117

    The Effects of Mung Bean Peptide and Its’ Complexes on the Treatment of Lead Poisoning by Wei Wei, Shue Wang, Xue-Jun Zhang, Jiu-Xun Zhang, Zheng-Wang Chen, Jia-Ying Huang, Ye-Wang Zhang

    Published 2021-01-01
    “…To investigate the effects of mung bean peptide and its’ complexes on promoting lead excretion and neuroprotection of zebrafish. …”
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    Article
  18. 118

    A Lipocalin-Derived Peptide Modulating Fibroblasts and Extracellular Matrix Proteins by Linda Christian Carrijo-Carvalho, Durvanei A. Maria, Janaina S. Ventura, Kátia L. P. Morais, Robson L. Melo, Consuelo Junqueira Rodrigues, Ana Marisa Chudzinski-Tavassi

    Published 2012-01-01
    “…The aim of this study is to investigate the effects of a synthetic peptide comprising the lipocalin sequence motif in fibroblasts. …”
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