Syndecan-4 is More Sensitive in Detecting Hypertensive Left Ventricular Diastolic Dysfunction in 2K2C Rats by Wenyue Dai, Yanqiu Liu, Fengjuan Yao, Wei Li, Jia Liu, Cuiling Li, Donghong Liu

“…The aim of this study was to investigate the changes of syndecan-4 (SDC-4) during the hypertensive period in two kidney-two clip (2K2C) hypertension rats and compare them to brain natriuretic peptide (BNP) and the echocardiographic parameters for diastolic function evaluation in the rat model of 2K2C hypertension. …”
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The Acute and Residual Effect of a Single Exercise Session on Meal Glucose Tolerance in Sedentary Young Adults by Kevin R. Short, Lauren V. Pratt, April M. Teague

“…Compared to No Ex and Prior Day Ex, which did not differ from one another, there were lower AUCs on the Same Day Ex trial for glucose (6%), insulin (20%) and C-peptide (14%). Thus, a single moderate intensity exercise session can acutely improve glycemic control but the effect is modest and short-lived.…”
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Simplified MS2 phage-like particle production including a novel maturation protein internal fusion affinity tag by Enos C. Kline, Rose Duong, Qin Wang, Barry R. Lutz

“…This advancement increases the number of available peptide display sites for the MS2 PLP platform with wide-ranging implications for future applications.…”
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Properties, Antioxidant and Antibacterial Activity of Southern Meagre Fish (<i>Argyrosomus hololepidotus</i>) Skin Gelatin Reinforced with Clove Bud Extract by Parvin Rostami, Ali Taheri, Mostafa Ghaffari

“…It can be concluded that phenolic compounds, such as eugenol in the clove extract, facilitated the formation of additional bonds between the peptide helixes of the gelatin, thereby enhancing the properties of the CE-incorporated films. …”
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GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites by Zhihua Sun, Peiyi Li, Xiao Wang, Shuchang Lai, Hong Qiu, Zhi Chen, Shidi Hu, Jie Yao, Jie Shen

“…Although glucagon-like peptide 1 receptor agonists (GLP-IRAs) show therapeutic effects for PCOS, its target and underlying mechanism remains elusive. …”
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Xanthomonas citri subsp. citri requires a polyketide cyclase to activate the type III secretion system for virulence by Shuying Zhu, Siyu Wu, Yanmin Liu, Zaibao Zhang, Huasong Zou

“…Results The PKC was determined to have a signal peptide, a START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) domain, and a GyrI-like small molecule binding domain. …”
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Potential Antimicrobe Producer of Endophytic Bacteria from Yellow Root Plant (Arcangelisia flava (L.)) Originated from Enggano Island by null Sipriyadi, null Masrukhin, Risky Hadi Wibowo, Welly Darwis, Salprima Yudha, Ismu Purnaningsih, Resli Siboro

“…These four isolates are identified as able to produce the bioactive compounds through the detection of polyketide synthase (PKS) and nonribosomal peptide synthase (NRPS)-encoding genes. B. cereus AKEBG23 has the highest inhibition against pathogenic bacteria, and according to the GC-MS analysis, five major compounds are allegedly involved in its antimicrobial activity such as butylated hydroxytoluene (BHT), diisooctyl phthalate, E-15-heptadecenal, 1-heneicosanol, and E-14-hexadecenal. …”
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Amylin: Localization, Effects on Cerebral Arteries and on Local Cerebral Blood Flow in the Cat by Lars Edvinsson, Peter J. Goadsby, Rolf Uddman

“…Amylin and adrenomedullin are two peptides structurally related to calcitonin gene-related peptide (CGRP). …”
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Sensory Neuropeptides and Endogenous Opioids Expression in Human Dental Pulp with Asymptomatic Inflammation: In Vivo Study by Daniel Chavarria-Bolaños, Hector Flores-Reyes, Nelson Lombana-Sanchez, Bernardino Cerda-Cristerna, Amaury Pozos-Guillen

“…This study quantified the expression of substance P (SP), calcitonin gene-related peptide (CGRP), β-endorphins (β-End), and methionine-enkephalin (Met-Enk) in human dental pulp following orthodontic intrusion. …”
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Identification and Characterization of Novel Perivascular Adventitial Cells in the Whole Mount Mesenteric Branch Artery Using Immunofluorescent Staining and Scanning Confocal Micro... by Chandra Somasundaram, Rahul K. Nath, Richard D. Bukoski, Debra I. Diz

“…A novel perivascular adventitial cell termed, adventitial neuronal somata (ANNIES) expressing the neural cell adhesion molecule (NCAM) and the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP), exists in the adult rat mesenteric branch artery (MBA) in situ. …”
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КЛАССИФИКАЦИЯ И ПОДТВЕРЖДЕНИЕ АНТИМИКРОБНОЙ АКТИВНОСТИ ПИЩЕВОГО ПЕПТИДА В ЭКСПЕРИМЕНТЕ INVITRO by Сергей Леонидович Тихонов, Наталья Валерьевна Тихонова, Инга Геннадьевна Пестова, Наталия Вадимовна Мерзлякова

“…На основании идентификации пептида по базе «Antimicrobial Peptide Database» установлено, что он на 40 % подобен антимикробному пептиду AP00450, действующему губительно на грамположительные и грамотрицательные бактерии. …”
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The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents by Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Efthymios Deligeoroglou, Zoe Iliodromiti

“…However, the quest for oxytocin receptor antagonists with a better pharmacological profile has led to the synthesis of peptide and nonpeptide molecules such as barusiban, retosiban, L-368,899, and SSR-126768A. …”
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Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation by Hiroki Shima, Akiko Inagaki, Takehiro Imura, Youhei Yamagata, Kimiko Watanabe, Kazuhiko Igarashi, Masafumi Goto, Kazutaka Murayama

“…Collagenases digest the peptide bond between Yaa and the subsequent Gly in Gly-Xaa-Yaa repeats. …”
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Role of insulin-like growth factor-2 in Alzheimer’s disease induced memory impairment and underlying mechanisms by Ruiqi Chen, Xing Lu, Anqi Xiao, Junpeng Ma, Junpeng Ma

“…Insulin-like growth factor-2 (IGF2), which is widely expressed in the central nervous system (CNS), has emerged as a crucial mechanism of synaptic plasticity and learning and memory, and many studies have indicated that this neurotrophic peptide is a viable candidate for treating and preventing AD-induced cognitive decline. …”
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NMR probing of copper–amyloid β1–16 interactions and self-assembly by Punnepalli Sunanda, Srinivasarao Raghothama, Uma Maheswari Devi Palempalli, Bankala Krishnarjuna

“…Atomic-level investigation of Aβ interaction with copper ions is essential for understanding the metal-mediated peptide self-assembly. In this study, we investigated copper ion–Aβ1–16 interactions using nuclear magnetic resonance (NMR) spectroscopy, circular dichroism, and transmission electron microscopy. …”
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Efficiency and Safety of Prolonged Levosimendan Infusion in Patients with Acute Heart Failure by Georgios Aidonidis, Ioannis Kanonidis, Vasileios Koutsimanis, Till Neumann, Raimund Erbel, Georgios Sakadamis

“…Clinical parameters, BNP (Brain Natriuretic Peptide) and signal-averaged-ECG data (SAECG) were recorded up to 72 hours. …”
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Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase by E. S. Dyudeeva, I. A. Pyshnaya

“…The best-known completely uncharged analogs of oligonucleotides – morpholine oligonucleotides and peptide nucleic acids – cannot be substrates for enzymes that process nucleic acids. …”
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Modulation of Vasomotive Activity in Rabbit External Ophthalmic Artery by Neuropeptides by Esmeralda Sofia Costa Delgado, Carlos Marques-Neves, Maria Isabel Sousa Rocha, José Paulo Pacheco Sales-Luís, Luís Filipe Silva-Carvalho

“…To investigate the vasomotive activity upon the external ophthalmic artery of vasointestinal peptide (VIP) and neuropeptide Y (NPY) using a previously developed model. …”
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Potential and development of cellular vesicle vaccines in cancer immunotherapy by Wenxi Zhao, Xianjun Li, Jialu Guan, Shuai Yan, Lizhi Teng, Xitong Sun, Yuhan Dong, Hongyue Wang, Weiyang Tao

“…Tumor exosomes carry antigens and MHC-peptide complexes, which can provide tumor antigens to antigen-processing cells and increase the chances of recognition of tumor antigens by immune cells. …”
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Relation of Asymmetric Dimethylarginine Levels to Macrovascular Disease and Inflammation Markers in Type 2 Diabetic Patients by Mustafa Celik, Serkan Cerrah, Mahmut Arabul, Aysen Akalin

“…We obtained fasting serum and plasma samples and measured HbA1c, fasting blood glucose, C-peptide, creatinine, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, hsCRP, fibrinogen, erythrocyte sedimentation rate, total homocysteine, and ADMA levels. …”
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