APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence by Jingyi Xie, Daniel G. Chen, William Chour, Rachel H. Ng, Rongyu Zhang, Dan Yuan, Jongchan Choi, Michaela McKasson, Pamela Troisch, Brett Smith, Lesley Jones, Andrew Webster, Yusuf Rasheed, Sarah Li, Rick Edmark, Sunga Hong, Kim M. Murray, Jennifer K. Logue, Nicholas M. Franko, Christopher G. Lausted, Brian Piening, Heather Algren, Julie Wallick, Andrew T. Magis, Kino Watanabe, Phil Mease, Philip D. Greenberg, Helen Chu, Jason D. Goldman, Yapeng Su, James R. Heath

“…Abstract Elucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR) specific to that antigen, and the T cell phenotype that emerges following antigen stimulation, remains a mostly unsolved problem, largely due to the lack of large data sets that can be mined to resolve such relationships. …”
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Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity by Lulu Song, Liping Cui, Hao Li, Na Zhang, Wenxiang Yang

“…Pt48115 contains a signal peptide with a secretory function and a transit peptide that can translocate Pt48115 to the host chloroplasts. …”
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Chemokines and Chemokine Receptors in Multiple Sclerosis by Wenjing Cheng, Guangjie Chen

“…Chemokines, which are small peptide mediators, can attract pathogenic cells to the sites of inflammation. …”
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In Vitro Activation and Inhibition of Recombinant EGFR Tyrosine Kinase Expressed in Escherichia coli by Jihene Elloumi-Mseddi, Karim Jellali, Sami Aifa

“…Protein expression was improved thanks to the deletion of a 13-amino acid peptide of the juxtamembrane region (JM). The recombinant proteins were produced as a glutathione S-transferase (GST) fusion in Escherichia coli, and the solubilisation was performed by sarkosyl addition during extraction. …”
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The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response by Pamela C. Ronald

“…These observations suggest a model where RaxST sulfates a molecule that contains a leader peptide, which is cleaved by the peptidase domain of the RaxB protein and secreted outside the bacterial cell by the RaxABC T1SS.…”
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Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus by Toratane Munegumi, Takafumi Yamada

“…The resulting mixture of the free molten aspartic acid was dehydrated to give peptide bonds. This study describes the thermal reactions of N-t-butyloxycarbonyl peptides (Boc-Gly-L-Asp, Boc-L-Ala-L-Asp, Boc-L-Val-L-Asp, and Boc-Gly-Gly-L-Asp) having an aspartic residue at the carboxyl terminus. …”
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Hexapeptide dalargin in clinical gastroenterology: 30 years' of clinical application of the drug by S. A. Bulgakov

“…Dalargin is the first synthetic opioid peptide agent created on the basis of endogenous leucineenkephaline. …”
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Hot pants: The emerging field of exercise mimetics, from hospital beds to the international space station by Kevin John

“…A relevant and current example of this is the enormous market demand for glucagon‐like peptide‐1 drugs for the management of obesity and type‐2 diabetes. …”
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High-throughput Identification of Phage-derived Imaging Agents by Kimberly A. Kelly, Paul A. Clemons, Amy M. Yu, Ralph Weissleder

“…The use of phage-displayed peptide libraries is a powerful method for selecting peptides with desired binding properties. …”
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Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity by Xiaoping Wang, Qiaoxia Wang

“…AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer.…”
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Weight Considerations in Pharmacotherapy for Type 2 Diabetes by Vicky Cheng, Sangeeta R. Kashyap

“…Dipeptidyl-peptidase-4 inhibitors are weight neutral, whereas glucagon-like peptide-1 analogs are associated with weight loss. …”
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Oxytocin in the Treatment of Psychiatric Disorders by Salim Cagatay KAGIZMAN, Cicek HOCAOGLU

“…Oxytocin is a peptide hormone that is most known for its role in reproduction. …”
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Liver metastases in gastroenteropancreatic neuroendocrine tumours – treatment methods by Paweł Gut

“…Pre-treatment staging often includes the biochemical assessment of serologic markers such as serotonin, insulin, vasoactive intestinal peptide, and chromogranin, even in patients without clinically apparent hormonal excess. …”
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Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy by Trond Lamark, Terje Johansen

“…The aggregates can be degraded by the proteasome and by chaperone-mediated autophagy only after dissolution into soluble single peptide species. Hence, protein aggregates as such are degraded by macroautophagy. …”
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Severe Transient Hyperglycemia in a Prediabetic Patient during Mild Acute Pancreatitis by Aura Diana Reghina, Silvia Craciun, Simona Fica

“…At two months from first presentation, pancreatic antibodies were negative, and the C-peptide level was normal. A1c level was 5.9% without insulin treatment. …”
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Short Communication: Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep by Andrew R. Williams

“…Bradykinin is a physiologically active peptide involved in vasodilation and smooth muscle contraction and is previously shown to be increased in gastrointestinal mucus during nematode challenge in sheep. …”
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Recent Advances in Potential Clinical Application of Ghrelin in Obesity by Christine Delporte

“…Ghrelin is a 28 amino acid peptide possessing a unique acylation on the serine in position 3 catalyzed by ghrelin O-acyltransferase (GOAT). …”
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Carrageenan-Free Diet Shows Improved Glucose Tolerance and Insulin Signaling in Prediabetes: A Randomized, Pilot Clinical Trial by Leo Feferman, Sumit Bhattacharyya, Erin Oates, Nicole Haggerty, Tianxiu Wang, Krista Varady, Joanne K. Tobacman

“…They had increases in C-peptide (p=0.029) and Matsuda Index (2.1±0.7 to 4.8±2.3; p=0.052) and declines in serum IL-8, serum galectin-3, and neutrophil phospho-(Ser307/312)-IRS1 (p=0.049, p=0.003, and p=0.006; paired t-tests, two tailed). …”
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Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders by Clara Camaschella, Laura Silvestri

“…At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. Disruption of these regulatory loops leads to genetic diseases characterized by iron deficiency (iron-refractory iron-deficiency anemia) or iron overload (hemochromatosis). …”
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Białka roślinne i ich funkcjonalne działania by Grażyna Nowicka

“…Hypotensive action of bioactive peptides derived from soy and lupin proteins has been reported. …”
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