Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study by Nermeen El-Moataz Bellah Ahmed, Masashi Murakami, Yujiro Hirose, Misako Nakashima

“…Moreover, treatment with DPSC secretome significantly decreased the cytotoxicity of Aβ peptide by increasing cell viability compared to nontreated cells. …”
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Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4 by Zheng-Cai Jia, Bing Ni, Ze-Min Huang, Yi Tian, Jun Tang, Jing-Xue Wang, Xiao-Lan Fu, Yu-Zhang Wu

“…MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials. …”
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Exploring associations between the FTO rs9939609 genotype and plasma concentrations of appetite-related hormones in adults with obesity. by Ann Kristin Hjelle de Soysa, Mette Langaas, Valdemar Grill, Catia Martins, Ingrid Løvold Mostad

“…This study explored associations of the rs9939609 genotypes to plasma concentrations of acylated ghrelin, active glucagon-like peptide 1 (GLP-1), and total peptide YY (PYY), and moderating effects of fat mass (FM), in 96 adults (69% female) with BMI ≥35 kg/m2, using a cross sectional observation study designed to have 1/3 of participants each with genotypes TT, AT and AA, respectively. …”
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Drug discovery: a multifactorial ecosystem by Fernando Albericio

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Human Islet Amyloid Polypeptide Fibril Binding to Catalase: A Transmission Electron Microscopy and Microplate Study by Nathaniel G. N. Milton, J. Robin Harris

“…Fibrils formed by the PrP 118-135 peptide with a Gly-Ala-Val-Val sequence also bound catalase. …”
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Acute Exercise and Appetite-Regulating Hormones in Overweight and Obese Individuals: A Meta-Analysis by Jessica Anne Douglas, Kevin Deighton, Jan Maria Atkinson, Vahid Sari-Sarraf, David John Stensel, Greg Atkinson

“…In lean individuals, acute aerobic exercise is reported to transiently suppress sensations of appetite, suppress blood concentrations of acylated ghrelin (AG), and increase glucagon-like peptide-1 (GLP-1) and peptide-YY (PYY). Findings in overweight/obese individuals have yet to be synthesised. …”
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The Effects of C. lacerata on Insulin Resistance in Type 2 Diabetes Patients by Arim Choi, Jung Hye Kim, Hye-Kyung Chung, Chul Woo Ahn, Hee Joon Choi, Yu-Sik Kim, Ji Sun Nam

“…Fasting, postprandial c-peptide, and insulin levels decreased at week 12 in the C. lacerata group (p<0.05). …”
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Maillard reaction products in plant-based dairy alternatives and their release during simulated gastrointestinal digestion by Kira Bieck, Franziska Ebert, Tilman Grune, Jana Raupbach

“…During simulated gastrointestinal digestion, CML and MG-H1 were released either as modified amino acid or in peptide-bound form, respectively. CEL was released to a significantly lesser extent in peptide-bound form. …”
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Development of a Gluten Standard from Relevant Sources of Wheat and Investigation into Gluten Content of Supplemental Enzymes Generated During Fermentation by Pyeongsug Kim, Natasha Kim Leeuwendaal, Jonathon Niño Charari, Joan Colom, John Deaton, Kieran Rea

“…During this process, potential allergenic products, including immunologically important gluten peptides, can be created. Current protocols for assessing the levels of these peptides often overlook the specific gluten source. …”
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Evaluation of the Presentation of Newly Diagnosed Type 1 Diabetes Mellitus in Children During and After the COVID-19 Pandemic by Semine Özdemir Dilek, Fatma Özgüç Çömlek

“…In the pandemic period, admissions with autoantibody positivity, low C-peptide and severe acidosis were more common.…”
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Anti-Inflammatory Effects of Adrenomedullin on Acute Lung Injury Induced by Carrageenan in Mice by Talero Elena, Di Paola Rosanna, Mazzon Emanuela, Emanuela Esposito, Motilva Virginia, Cuzzocrea Salvatore

“…Adrenomedullin (AM) is a 52 amino acid peptide that has shown predominant anti-inflammatory activities. …”
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Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α by Bo Liu, Xin Gong, Shaohong Chang, Peng Sun, Jun Wu

“…Nα-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. …”
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Immunoinformatics design of a novel multiepitope vaccine candidate against non-typhoidal salmonellosis caused by Salmonella Kentucky using outer membrane proteins A, C, and F. by Elayoni E Igomu, Paul H Mamman, Jibril Adamu, Maryam Muhammad, Abubarkar O Woziri, Manasa Y Sugun, John A Benshak, Kingsley C Anyika, Rhoda Sam-Gyang, David O Ehizibolo

“…To boost the immunogenicity of the peptide construct, fliC from S. Typhimurium was included at the N-terminal. …”
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Cryo-EM structure of the calcium-sensing receptor complexed with the kokumi substance γ-glutamyl-valyl-glycine by Hiroki Yamaguchi, Seiji Kitajima, Hiroshi Suzuki, Shota Suzuki, Kouki Nishikawa, Akiko Kamegawa, Yoshinori Fujiyoshi, Kazutoshi Takahashi, Uno Tagami, Yutaka Maruyama, Motonaka Kuroda, Masayuki Sugiki

“…These findings elucidate the molecular basis of kokumi peptide recognition by the CaSR and contribute to a better understanding of positive allosteric modulators of the CaSR. …”
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Sp17 Protein Expression and Major Histocompatibility Class I and II Epitope Presentation in Diffuse Large B Cell Lymphoma Patients by Kamel Ait-Tahar, Amanda P. Anderson, Martin Barnardo, Graham P. Collins, Chris S. R. Hatton, Alison H. Banham, Karen Pulford

“…A significant γ-interferon CTL response was detected in peripheral blood mononuclear cells of 13/31 DLBCL patients following short-term cell stimulation with two novel HLA-A⁎0201 peptides and one previously reported HLA-A⁎0101-restricted nine-mer Sp17 peptide. …”
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Survodutide - Novel Anti Obesity Drug by Irtiqa Ayani Rathore, Sana Malik, Amarjeet Singh, Vishal R Tandon, Annil Mahajan

“… Survodutide (BI 456906) is a novel, dual agonist of glucagon and glucagon-like peptide-1 (GLP-1) receptors developed as a once-weekly subcutaneous injection for the management of obesity. …”
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Arginase-1-specific T cells target and modulate tumor-associated macrophages by Mads Hald Andersen, Inés Lecoq, Ayako Wakatsuki Pedersen, Evelina Martinenaite, Shamaila Munir Ahmad, Maria Perez-Penco, Lucia Lara de la Torre, Marion Chapellier, Lars Rønn Olsen, Mia Aaboe-Jørgensen, Hannah Jorinde Glöckner, Anne Mette Askehøj Rømer

“…MHC class II-restricted Arg-1 peptide presentation by macrophages was confirmed by immunopeptidomics. …”
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NT‐ProBNP and high‐sensitivity troponin T as screening tests for subclinical chronic heart failure in a general population by Maria Averina, Michael Stylidis, Jan Brox, Henrik Schirmer

“…Conclusions N‐terminal pro‐brain natriuretic peptide and hs‐troponin T are suboptimal screening tools for subclinical HF in a general population due to low sensitivity.…”
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Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents by Sun-Young Kim, Minsun Kim, Youngman Oh, Dae-Yeol Lee

“…Serum IGF-I and IGFBP-3 levels were correlated with age, HbA1c, C-peptide, insulin, and HOMA-IR in the NGT group. However, these relationships were altered in patients with glucose intolerance, especially in those with DM. …”
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Giese-type alkylation of dehydroalanine derivatives via silane-mediated alkyl bromide activation by Perry van der Heide, Michele Retini, Fabiola Fanini, Giovanni Piersanti, Francesco Secci, Daniele Mazzarella, Timothy Noël, Alberto Luridiana

“…The reaction can be performed in a phosphate-buffered saline (PBS) solution and shows post-functionalization prospects through pathways involving classical peptide chemistry.…”
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