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701
Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity
Published 2025-01-01“…Pt48115 contains a signal peptide with a secretory function and a transit peptide that can translocate Pt48115 to the host chloroplasts. …”
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702
Chemokines and Chemokine Receptors in Multiple Sclerosis
Published 2014-01-01“…Chemokines, which are small peptide mediators, can attract pathogenic cells to the sites of inflammation. …”
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703
In Vitro Activation and Inhibition of Recombinant EGFR Tyrosine Kinase Expressed in Escherichia coli
Published 2013-01-01“…Protein expression was improved thanks to the deletion of a 13-amino acid peptide of the juxtamembrane region (JM). The recombinant proteins were produced as a glutathione S-transferase (GST) fusion in Escherichia coli, and the solubilisation was performed by sarkosyl addition during extraction. …”
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704
The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response
Published 2014-01-01“…These observations suggest a model where RaxST sulfates a molecule that contains a leader peptide, which is cleaved by the peptidase domain of the RaxB protein and secreted outside the bacterial cell by the RaxABC T1SS.…”
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705
Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus
Published 2017-01-01“…The resulting mixture of the free molten aspartic acid was dehydrated to give peptide bonds. This study describes the thermal reactions of N-t-butyloxycarbonyl peptides (Boc-Gly-L-Asp, Boc-L-Ala-L-Asp, Boc-L-Val-L-Asp, and Boc-Gly-Gly-L-Asp) having an aspartic residue at the carboxyl terminus. …”
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706
Hexapeptide dalargin in clinical gastroenterology: 30 years' of clinical application of the drug
Published 2016-08-01“…Dalargin is the first synthetic opioid peptide agent created on the basis of endogenous leucineenkephaline. …”
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707
Hot pants: The emerging field of exercise mimetics, from hospital beds to the international space station
Published 2024-11-01“…A relevant and current example of this is the enormous market demand for glucagon‐like peptide‐1 drugs for the management of obesity and type‐2 diabetes. …”
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708
High-throughput Identification of Phage-derived Imaging Agents
Published 2006-01-01“…The use of phage-displayed peptide libraries is a powerful method for selecting peptides with desired binding properties. …”
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709
Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
Published 2018-01-01“…AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer.…”
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710
Weight Considerations in Pharmacotherapy for Type 2 Diabetes
Published 2011-01-01“…Dipeptidyl-peptidase-4 inhibitors are weight neutral, whereas glucagon-like peptide-1 analogs are associated with weight loss. …”
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711
Oxytocin in the Treatment of Psychiatric Disorders
Published 2023-09-01“…Oxytocin is a peptide hormone that is most known for its role in reproduction. …”
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712
Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy
Published 2012-01-01“…The aggregates can be degraded by the proteasome and by chaperone-mediated autophagy only after dissolution into soluble single peptide species. Hence, protein aggregates as such are degraded by macroautophagy. …”
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713
Severe Transient Hyperglycemia in a Prediabetic Patient during Mild Acute Pancreatitis
Published 2015-01-01“…At two months from first presentation, pancreatic antibodies were negative, and the C-peptide level was normal. A1c level was 5.9% without insulin treatment. …”
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714
Short Communication: Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep
Published 2012-01-01“…Bradykinin is a physiologically active peptide involved in vasodilation and smooth muscle contraction and is previously shown to be increased in gastrointestinal mucus during nematode challenge in sheep. …”
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715
Recent Advances in Potential Clinical Application of Ghrelin in Obesity
Published 2012-01-01“…Ghrelin is a 28 amino acid peptide possessing a unique acylation on the serine in position 3 catalyzed by ghrelin O-acyltransferase (GOAT). …”
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716
Carrageenan-Free Diet Shows Improved Glucose Tolerance and Insulin Signaling in Prediabetes: A Randomized, Pilot Clinical Trial
Published 2020-01-01“…They had increases in C-peptide (p=0.029) and Matsuda Index (2.1±0.7 to 4.8±2.3; p=0.052) and declines in serum IL-8, serum galectin-3, and neutrophil phospho-(Ser307/312)-IRS1 (p=0.049, p=0.003, and p=0.006; paired t-tests, two tailed). …”
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717
Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders
Published 2011-01-01“…At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. Disruption of these regulatory loops leads to genetic diseases characterized by iron deficiency (iron-refractory iron-deficiency anemia) or iron overload (hemochromatosis). …”
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718
Białka roślinne i ich funkcjonalne działania
Published 2006-12-01“…Hypotensive action of bioactive peptides derived from soy and lupin proteins has been reported. …”
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719
GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism
Published 2025-02-01“…We also discuss recent findings that highlight the interaction of distinct peptide-GPCR systems in modulating complex feeding behaviors.…”
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720
Insulin Autoimmune Syndrome: A Systematic Review
Published 2023-01-01“…High levels of insulin autoantibodies are found in patients, and C-peptide is not parallel to insulin, which could be diagnostic. …”
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