ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics by Lennox Chitsike, John Krstenansky, Penelope J. Duerksen-Hughes

“…Using our optimized AlphaScreen™ assay, we evaluated the activity and specificity of these peptides and small molecules in inhibiting the binding of ACE2 : S1 RBD. …”
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Enhanced extracellular production of alpha-lactalbumin from Bacillus subtilis through signal peptide and promoter screening by Yuqi Zhu, Pengdong Sun, Chunjian Li, Yu Zhang, Yu Wang, Jingyuan Li, Yanfeng Liu, Jian Chen, Yang Deng

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Predicting prognosis using stroke-heart indicator: brain natriuretic peptide in patients with aneurysmal subarachnoid hemorrhage by Jionghao Xue, Jionghao Xue, Fa Lin, Fa Lin, Minghao Liu, Minghao Liu, Wenxiong Song, Wenxiong Song, Runting Li, Runting Li, Yu Chen, Yu Chen, Jun Yang, Jun Yang, Heze Han, Heze Han, Yitong Jia, Yitong Jia, Xiaolin Chen, Xiaolin Chen, Rong Wang, Rong Wang, Yuanli Zhao

“…ObjectiveThis study aims to explore the correlation between brain natriuretic peptide (BNP) levels and prognosis in patients suffering from aneurysmal subarachnoid hemorrhage (aSAH).MethodsThis retrospective study included patients diagnosed with aneurysmal subarachnoid hemorrhage (aSAH) at Beijing Tiantan Hospital between January 2015 and September 2021. …”
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Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4 by Patrícia Brigatte, Odair Jorge Faiad, Roberta Cornélio Ferreira Nocelli, Richardt G. Landgraf, Mario Sergio Palma, Yara Cury, Rui Curi, Sandra Coccuzzo Sampaio

“…The treatment with CTX raised plasma concentrations of lipoxin A4 and its natural analogue 15-epi-LXA4, an effect mediated by formyl peptide receptors (FPRs). In fact, the treatment with Boc-2, an inhibitor of FPRs, abolished the increase in plasma levels of these mediators triggered by CTX. …”
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Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions by Walrant, Astrid, Tazi, Farah, Khemaissa, Sonia, Sagan, Sandrine

Subjects: “…Cell-penetrating peptide…”
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TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B by Letizia Mezzasoma, Lucio Cagini, Cinzia Antognelli, Francesco Puma, Eugenio Pacifico, Vincenzo Nicola Talesa

“…In particular, we found that TNF-α induced a decrease of arial natriuretic peptide, natriuretic peptide receptor-1, aquaporin-1 and aquaporin-5 and an increase of brain natriuretic peptide with a different involvement of nuclear factor-κB and mitogen-activated protein kinases signaling pathway activation. …”
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New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor by K. Ryliškienė, D. Jatužis, A. Vaitkus

“…During the last decade, blocking calcitonin gene-related peptide (CGRP) has emerged as a possible mechanism for preventing migraine attacks, and monoclonal antibodies against CGRP and its receptor for the specific migraine prophylaxis have been developed. …”
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-Tyrosine Confers Residualizing Properties to a -Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies by Fook T. Lee PhD, Ingrid J. G. Burvenich PhD, Nancy Guo MBBS, MSc, Pece Kocovski BSc (Honors), Henri Tochon-Danguy PhD, Uwe Ackermann PhD, Graeme J. O’Keefe PhD, Sylvia Gong PhD, Angela Rigopoulos BSc, MSc, Zhanqi Liu MBBS, PhD, Hui K. Gan MBBS, FRACP, PhD, Andrew M. Scott MBBS, FRACP, MD

“…Methods: The anti-epidermal growth factor receptor antibody ch806 was radiolabeled directly or indirectly with isotopes and various residualizing peptides. Azido-derivatized radiolabeled peptides were conjugated to dibenzylcyclooctyne-derivatized ch806 antibody via click chemistry. …”
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Elucidation of peptide screen for targeted identification of Yersinia pestis by nano-liquid chromatography tandem mass spectrometry by Priya Rani, Syed Imteyaz Alam, Sandeep Singh, Subodh Kumar

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Virtual screening and directional preparation of xanthine oxidase inhibitory peptides derived from hemp seed protein by Xiaoni Huang, Jiajun Liao, Ping Shi, Xiaodong Pei, Chenghua Wang

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Phage display technology in ecotoxicology: phage display derived unique peptide for copper identification in aquatic samples by Marta Sosnowska, Tomasz Łęga, Marcin Olszewski, Beata Gromadzka

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Identification and dipeptidyl peptidase IV (DPP-IV) inhibitory activity verification of peptides from mouse lymphocytes by Juan Wang, Yujia Xie, Yuanyuan Luan, Tingting Guo, Shanshan Xiao, Xingxing Zeng, Shaohui Zhang

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Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria by Filippo Fratini, Chiara Pecorini, Ilaria Resci, Emma Copelotti, Francesca Paola Nocera, Basma Najar, Simone Mancini

“…In light of these considerations, the synergistic use of essential oils and Antimicrobial Peptides (AMPs) seems a viable strategy. In this study, we assessed the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Fractional Inhibitory Concentration (FIC) of three Essential Oils (EOs): winter savory (<i>Satureja montana</i>), bergamot (<i>Citrus bergamia</i>) and cinnamon (<i>Cinnamomum zeylanicum</i>) and of the insect antimicrobial peptide Cecropin A (CecA), alone and in combination with EOs, against two Gram-negative ATCC bacterial strains: <i>Escherichia coli</i> and <i>Salmonella enterica</i> serovar Typhimurium. …”
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Glucagon like peptide-1 (GLP-1) agonists and cardiometabolic protection: historical development and future challenges by Francisco Westermeier, Enrique Z. Fisman

Subjects: “…Glucagon-like peptide-1…”
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RETRACTED: A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice by Shireen Mohammad, Sura Al Zoubi, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Nadine Krieg, Bianka Wissuwa, Bianka Wissuwa, Gustavo Ferreira Alves, Gareth S. D. Purvis, Gareth S. D. Purvis, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Andrea Baragetti, Andrea Baragetti, Alberico Luigi Catapano, Alberico Luigi Catapano, Alberico Luigi Catapano, Egle Solito, Egle Solito, Elisabeth Zechendorf, Tobias Schürholz, Wilmar Correa-Vargas, Klaus Brandenburg, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, Muhammad M. Yaqoob, Lukas Martin, Lukas Martin, Christoph Thiemermann

Subjects: “…peptide 19-2.5…”
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Fish-derived hepcidins in cancer treatment: a scoping review by Wan-Atirah Azemin, Syarifah Ab Rashid, Noraini Philip, Abdul Manaf Ali, Mohd Shahir Shamsir

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The dipeptide carnosine alleviates acute pancreatitis in an experimental model by Heresh Rezaei, Saeed Heidari, Mohammad Mehdi Ommati, Babak Taheri, Forouzan Khodaei, Mohammad Ali Dehghani, Ayeh Rowhanirad, Azadeh Veisi-Goshtasb, Zahra Honarpishefard, Negar Azarpira, Hossein Niknahad, Reza Heidari

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Structure Characterization of a Disordered Peptide Using In-Droplet Hydrogen/Deuterium Exchange Mass Spectrometry and Molecular Dynamics by Mohammad A. Rahman, Mst Nigar Sultana, Daud Sharif, Sultan Mahmud, Justin Legleiter, Peng Li, Blake Mertz, Stephen J. Valentine

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Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. by Yuqing Wang, Ayrea Hurley, Marco De Giorgi, Mark R Tanner, Rong-Chi Hu, Michael W Pennington, William R Lagor, Christine Beeton

“…In conclusion, the AAV8-based delivery of ShK-235 was highly effective in inducing the secretion of functional Kv1.3-blocking peptide in mouse, but not rat, hepatocytes yet did not reduce obesity in mice fed a high-fat diet.…”
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The Effect of Calcitonin Gene-Related Peptide (CGRP) on the Cytosolic Calcium Concentration and Force in Rat Intramural Coronary Arteries by M. Sheykhzade, N.C.B. Nyborg

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