Eptinezumab-jjmr, a humanized monoclonal specific to Calcitonin Gene Related Peptide, for the preventive treatment of migraine in adults by Amnon A. Berger, Joseph Keefe, Cain W. Stark, Matthew Moore, Giovanni F. Ramírez, Julia R. Cucarola, Andrew H. Han, Alan D. Kaye, Latha Ganti

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A comparative analysis of sequence composition in different lots of a phage display peptide library during amplification by Anders Wilgaard Sinkjaer, Ane Beth Sloth, Amanda Oester Andersen, Malte Jensen, Babak Bakhshinejad, Andreas Kjaer

“…Conclusion Our results highlight tremendous heterogeneity in the peptide composition of different lots of the same type of naïve phage display library, and the divergent evolution of their compositional features during amplification rounds at the amino acid, peptide, and motif levels. …”
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Effects of NSAIDs on the Release of Calcitonin Gene-Related Peptide and Prostaglandin E2 from Rat Trigeminal Ganglia by Vittorio Vellani, Giorgia Moschetti, Silvia Franchi, Chiara Giacomoni, Paola Sacerdote, Giada Amodeo

“…The trigeminal ganglia and calcitonin gene-related peptide (CGRP) have been implicated in the pathophysiology of migraine. …”
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High-level biosynthesis and purification of the antimicrobial peptide Kiadin based on non-chromatographic purification and acid cleavage methods by Liangjun Zheng, Fengyi Yang, Chen Wang, Muhammad Zafir, Zishuo Gao, Pilong Liu, Fatma A. El-Gohary, Xin Zhao, Huping Xue

Subjects: “…Antimicrobial peptide…”
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NMO-IgG and AQP4 Peptide Can Induce Aggravation of EAMG and Immune-Mediated Muscle Weakness by Tehila Mizrachi, Livnat Brill, Malcolm Rabie, Yoram Nevo, Yakov Fellig, Mayan Zur, Dimitrios Karussis, Oded Abramsky, Talma Brenner, Adi Vaknin-Dembinsky

“…To verify whether coexisting autoimmune disease may exacerbate experimental autoimmune MG, we tested whether active immunization with AQP4 peptides or passive transfer of NMO-Ig can affect the severity of EAMG. …”
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One step closer to solving the mystery of the anti‐inflammatory effects of glucagon‐like peptide‐1 receptor agonists by Hirotaka Watada

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Lowering B-type natriuretic peptide levels and increasing cardiac function: the role of levosimendan in the treatment of heart failure by Jianfeng Meng, Ye Zuo

“…Objective In this study, we examined whether levosimendan could lower B-type natriuretic peptide (BNP) and improve cardiac function in patients with heart failure who have diuretic resistance and low ejection fraction. …”
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Multi-active phlorotannins boost antimicrobial peptide LL-37 to promote periodontal tissue regeneration in diabetic periodontitis by Cancan Li, Luowen Du, Yingying Xiao, Lei Fan, Quanli Li, Chris Ying Cao

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Ceftriaxone-Induced Immune Hemolytic Anemia: In Vitro Reversal with Peptide Inhibitor of Complement C1 (PIC1) by Kenji M. Cunnion, Lisa M. Feagin, Michael F. Chicella, Cortney L. Kaszowski, Pamela S. Hair, Jessica Price, William C. Owen

“…We confirmed that ceftriaxone initiated a classical complement pathway-mediated hemolysis by in vitro reversal with peptide inhibitor of complement C1 (PIC1).…”
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Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions by J.A. Fischer, W. Born, R. Muff

“…For the related bioactive peptides, receptor-binding sites linked to cAMP stimulation and to a lesser extent to the phospholipase C signaling pathway have been identified in tissue specific manner. …”
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β-glucan attenuates intestinal ischemia-reperfusion injury in mice by promoting glucagon-like peptide-1 secretion by WANG Wei, HAN Ben, SUN Lihua

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Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain by Zhong-Sen Qu, Liang Li, Xiao-Jiang Sun, Yu-Wu Zhao, Jin Zhang, Zhi Geng, Jian-Liang Fu, Qing-Guo Ren

“…Here we tried to investigate the production of amyloid-β peptides (Aβ) and phosphorylation of microtubule-associated protein tau in DM rats and elucidate the role of GSK-3 and Akt (protein kinase B, PKB) in these processes. …”
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Development of detection system for lead ions in mixture solutions using UV-Vis measurements with peptide immobilized microbeads by Shuhei Yoshida, Koki Yoshida, Yoshio Hamada, Takaaki Tsuruoka, Kenji Usui

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In Vitro Characterization of Fluted Pumpkin Leaf Protein Hydrolysates and Ultrafiltration of Peptide Fractions: Antioxidant and Enzyme-Inhibitory Properties by Akinsola Albert Famuwagun, Adeola Monisola Alashi, Saka Olasunkanmi Gbadamosi, Kehinde Adekunbi Taiwo, Joseph Durodoluwa Oyedele, Odunayo Clement Adebooye, Rotimi Emmanuel Aluko

“…The hydrolysate peptides had a high content of hydrophobic amino acids but low levels of sulfur-containing amino acids, when compared to protein of FLI. …”
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Elevated plasma levels of endothelin are associated with the severity of sepsis and presence of shock in contrast to the levels of atrial natriuretic peptide by A. Beishuizen, J. M. Götz, L. Kip, C. Haanen, I. Vermes

“…Immunoreactive endothelin (ETi) and atrial natriuretic peptide (ANPi) blood levels were measured by radioimmunoassay in patients with clinically defined sepsis. …”
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Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphosphate Aldolase Protein Using Immunoinformatics by Mustafa Elhag, Ruaa Mohamed Alaagib, Nagla Mohamed Ahmed, Mustafa Abubaker, Esraa Musa Haroun, Sahar Obi Abd Albagi, Mohammed A. Hassan

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Plasma Levels of High-Mobility Group Box 1 during Peptide Vaccination in Patients with Recurrent Ovarian Cancer by Kayoko Waki, Kouichiro Kawano, Naotake Tsuda, Kimio Ushijima, Kyogo Itoh, Akira Yamada

“…However, there is no information on HMGB1 levels in cancer patients treated with peptide vaccination. In the present study, we investigated the plasma levels of HMGB1 during personalized peptide vaccination in patients with recurrent ovarian cancer. …”
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Underlying mechanism of electrospun starch-based nanofiber mats to adsorb the key off-odor compounds of oyster peptides by Linfan Shi, Zhouru Li, Shiqin Qing, Zhongyang Ren, Ping Li, Songnan Li, Wuyin Weng

“…The solid-phase adsorption principles and fundamental mechanism of isobutyric acid, 1-octen-3-ol, and octanal (three key off-odor compounds of oyster peptides) were explored using electrospun octenyl succinylated starch-pullulan (OSS-PUL) nanofiber mat. …”
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Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions by Hyeon-Jeong Hwang, Youngsang Nam, Chanhee Jang, Eun La Kim, Eun Seo Jang, Yeo Jin Lee, Seoung Rak Lee

Subjects: “…ribosomally synthesized and post-translationally modified peptides…”
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Correlation between B-Type Natriuretic Peptide and Functional/Cognitive Parameters in Discharged Congestive Heart Failure Patients by Laura Leto, Marzia Testa, Mauro Feola

“…The determination of B-type natriuretic peptides (BNP) may have a role in the diagnosis of heart failure (HF) or guiding HF therapy. …”
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